한빛사 논문
Seung-Hoon Uma,b, Yong-Woo Chunga, Youngmin Seoa, Hyunseon Seoa, Myoung-Ryul Oka, Yu-Chan Kima,c, Hyung-Seop Hana, Justin J. Chunga, James R. Edwardsd, and Hojeong Jeona,c,*
aCenter for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea
bDental Research Institute and Department of Biomaterials Science, Seoul National University, Daehakro 101, Jongno-gu, Seoul 03080, Republic of Korea
cDivision of Bio-Medical Science and Technology, KIST School, Korea University of Science and Technology, Seoul 02792, Republic of Korea
dBotnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford OX3 7LD, UK
*To whom correspondence should be addressed.
Abstract
Owing to enhanced biocompatibility and osseointegration, hydroxyapatite (HAp) coatings are often applied to biomedical devices that are implanted directly on the bone. Although various HAp coating techniques have been developed, they are restricted due to the time‐consuming HAp synthesis and additional coating processes. Herein, the development of a rapid single‐step method for simultaneous synthesis and coating of HAp via nanosecond laser surface treatment is described. In the conventional HAp‐coating method, the resulting interface between the HAp layer and the base material is clearly distinguished. However, in this method, HAp synthesis and coating occur simultaneously via the melting of the base material (i.e., titanium, polyetheretherketone, and polycaprolactone) to form a gradient HAp‐base material composite coating layer. The resultant coating layer on a titanium surface exhibits a binding force of 31.7–47.2 N, which is sufficient for medical implant applications. Changing the laser irradiation conditions provides quantitative adjustment of the HAp formation process and coating layer thickness. Furthermore, the resulting HAp coating layer better facilitates the attachment of bone cells. These results offer a breakthrough in the surface treatment of bone‐bonding sites of metal and polymer biomedical devices.
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TOP52020년 후보
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