한빛사 인터뷰
1. 논문관련 분야의 소개, 동향, 전망을 설명, 연구과정에서 생긴 에피소드
With the continuous development in nanozyme field, many researchers are focusing and working on improving the nanoparticles/nanomaterials enzyme mimicking activity. This study is conducted in relation to this topic for investigating how plant extract based green nanoparticles behave as nanozyme. In this study, we prepared gold nanoparticles of rhombohedron and decahedron shapes. Further, we checked the efficacy of prepared nanoparticles for catalyzing multienzyme cascade reaction (glucose oxidase and peroxidase mimicking activity). First, with glucose oxidase mimicking activity, glucose is oxidized to gluconic acid and H2O2. Second, the in situ generated H2O2 by glucose oxidation assists the subsequent peroxidase mimicking reaction that oxidizes the chromogenic substrate 3,3′,5,5′-tetramethylbenzidine. This reaction confirms the dual enzyme activity of green gold nanoparticles. In addition, comparison of chemically and green synthesized gold nanoparticles showed the effectiveness of green gold nanoparticles. The plant extract synthesized gold nanoparticles showed long term stability and good glucose oxidase/peroxidase mimicking activity. The findings from our study provides new insights regarding the investigation of green synthesized nanoparticles/nanomaterials as multienzyme substitutes in different applications.
2. 연구를 진행했던 소속기관 또는 연구소에 대해 소개 부탁드립니다.
Presently, I am Postdoctoral Researcher at Chungbuk National University, under the guidance of Professor Beom Soo Kim. Our laboratory works on multidisciplinary areas, such as green synthesis of nanoparticles, microbial production of biopolymers, and production of value added biochemicals (e.g. NMN, carotenoids, lactic acid, etc). In addition, we are working on the applications of nanoparticles for various enzyme like activities, and lignocellulose degradation. (Professor Beom Soo Kim’s Lab website: https://sites.google.com/view/cbnu-bel/%ED%99%88?authuser=0).
3. 연구활동 하시면서 평소 느끼신 점 또는 자부심, 보람
Positive emotions like gratitude, compassion, and pride encourage me to be more persistent in reaching my research goals. I believe that anything can be achieved by listening and surrendering to your heart’s desires. The day I truly listened to what I wanted to do in life, everything I did brought me closer to achieving my goal. As if destiny was holding me by the hand and leading me to where I am today. Lastly I would like to say to everyone, no matter how big or small your dream is, it can come true; all you’ve got to do is hold out for it.
4. 이 분야로 진학하려는 후배들 또는 유학준비생들에게 도움이 되는 말씀을 해 주신다면?
Doing a PhD is not a small undertaking. What really helped me keep going is that I was researching in an area and regarding a topic that I am truly passionate about. I love reading, writing, thinking and talking about my topic more generally, and this keeps me motivated and engaged even when things aren’t always going the way I planned. At the same time, the many challenges that can crop up mean that it’s important to keep an open mind and be flexible. While I was able to keep focusing on the research questions that interested me, with support and guidance, I adjusted my approach to overcome some of the initial issues I had with my experimentation. In the end, this led me to do something completely new, and focusing on credibility. Well, we all develop certain ambitions as we move through life. Even if we don't have a specific objective in mind, we constantly envision ourselves in a certain light in the future. But, in order to achieve, we must first plan properly and then execute. In all of this, we need determination and the help of others to get through this. The most important and undisputed factor to achieve your goal and take on the journey towards is hard work. Only your sincere efforts will help you overcome any difficulty that comes your way.
Keep faith in yourself and be true to your work. That is the underlying mantra to success in any field. There is nothing that you cannot achieve if you are willing to work hard. So, never limit your dreams. Let your dreams fly but be resolute and ready to put in your 100% through the journey. You will be really happy and satisfied when you see your hard work bearing fruits.
5. 연구활동과 관련된 앞으로의 계획이 있으시다면?
After earning few years of Postdoctoral researcher experience, I would actively pursue a career in academics and research. With my chemical engineering knowledge combined with expertise in green synthesis of nanomaterials, I believe I will be able to conduct more multidisciplinary research in nano-biocatalysis field.
6. 다른 하시고 싶은 이야기들....
I believe that the most important factor in surviving and thriving in the PhD was having great support networks and guidance. I would like to express my gratitude to Professor Beom Soo Kim for guiding and supporting me throughout my research at CBNU. Looking at the professor, I could see how much effort he used to put into completing any work, giving critical comments on manuscripts and research discussion in every lab meeting. I was able to learn many things that researchers have to do besides experiments and paper writing. I would like to thank my fellow lab members and CBNU Research Center for their great help. Lastly, I would like to express my gratitude to my beloved mother, father, and other family members who believed in me.
#green synthesis
#nanomaterials
#nanozyme
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