한빛사 논문
Sung Woon Kang1,#, Ji Yeun Kim1,#, Heedo Park2,3,#, So Yun Lim1, Jeonghun Kim2,3, Seongman Bae1, Jiwon Jung1, Min Jae Kim1, Yong Pil Chong1, Sang-Oh Lee1, Sang-Ho Choi1, Yang Soo Kim1, Man-Seong Park2,3,* Sung-Han Kim1,*
1Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
2BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul 02841, Republic of Korea
3Department of Microbiology, Institute for Viral Diseases, Biosafety Center, College of Medicine, Korea University, Seoul, South Korea
#These authors equally contributed to the work.
*Corresponding author.
Abstract
Dear Editor:
Initial data after the rollout of COVID-19 vaccines revealed more than 90% effectiveness with infrequent breakthrough infection (1). Furthermore, individuals with breakthrough infection had a lower initial genomic viral load than unvaccinated individuals with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection, so transmission potential from those with breakthrough infection was low (2). However, data on the comparison of transmission potential between fully and partially or unvaccinated individuals with SARS-CoV-2 infections in the era of the delta variant are lacking. We thus compared the secondary attack rate and viable viral shedding kinetics with viral culture and subgenomic RNA detection through the dense sampling of respiratory specimens between fully vaccinated individuals and partially or unvaccinated individuals with SARS-CoV-2 delta variant infection.
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