한빛사 논문
Ying Sun 1,4, Dong-Ha Oh 2,4, Lina Duan1, Prashanth Ramachandran1, Andrea Ramirez1, Anna Bartlett3, Kieu-Nga Tran2, Guannan Wang 2, Maheshi Dassanayake2 and José R. Dinneny 1,*
1Department of Biology, Stanford University, Stanford, CA, USA. 2Department of Biological Sciences, Louisiana State University, Baton Rouge, LA, USA. 3Genomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA. 4These authors contributed equally: Ying Sun, Dong-Ha Oh.
*Corresponding author.
Abstract
The phytohormone abscisic acid (ABA) is a central regulator of acclimation to environmental stress; however, its contribution to differences in stress tolerance between species is unclear. To establish a comparative framework for understanding how stress hormone signalling pathways diverge across species, we studied the growth response of four Brassicaceae species to ABA treatment and generated transcriptomic and DNA affinity purification and sequencing datasets to construct a cross-species gene regulatory network (GRN) for ABA. Comparison of genes bound directly by ABA-responsive element binding factors suggests that cis-factors are most important for determining the target loci represented in the ABA GRN of a particular species. Using this GRN, we reveal how rewiring of growth hormone subnetworks contributes to stark differences in the response to ABA in the extremophyte Schrenkiella parvula. Our study provides a model for understanding how divergence in gene regulation can lead to species-specific physiological outcomes in response to hormonal cues.
논문정보
관련 링크
연구자 ID
관련분야 연구자보기
소속기관 논문보기
관련분야 논문보기
해당논문 저자보기