한빛사 논문
Dongseok Lim1,2, Dongwook Kim1,2, Ji Won Um1, Jaewon Ko1,*
1Department of Brain Sciences, Daegu Gyeongbuk Institute of Science Technology (DGIST), Daegu 42988, South Korea
2These authors contributed equally.
*Corresponding author.
Abstract
Multiple synaptic adhesion proteins are thought to collectively define the properties of specific synapses and thereby shape the architectures of neural circuits. Growing evidence supports a molecular model in which a set of central hub proteins interacts with a vast number of other proteins to organize multifarious synaptic adhesion pathways. However, several fundamental open questions remain, partly owing to drawbacks in current approaches and interpretations. In this opinion, we provide an overview of synaptic adhesion pathways, underscoring open questions to be addressed in future work, and highlighting approaches for advancing understanding of synaptic adhesion processes.
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