한빛사 논문
Abdelmonaim Azzouza, Lamia Hejjia, Ki-Hyun Kimb,*, Deepak Kukkarc, Badredine Souhaila, Neha Bhardwajd, Richard J.C. Browne, Wei Zhangf
aDepartment of Chemistry, Faculty of Science, University of Abdelmalek Essaadi, B.P. 2121, M'Hannech II, 93002, Tétouan, Morocco
bDepartment of Civil and Environmental Engineering, Hanyang University, 222 Wangsimni-Ro, Seoul, 04763, South Korea
cDepartment of Nanotechnology, Sri Guru Granth Sahib World University, Fatehgarh Sahib, 140406, Punjab, India
dDepartment of Biotechnology, University Institute of Engineering Technology (UIET), Panjab University, Chandigarh, India
eEnvironment Department, National Physical Laboratory, Teddington, TW11 0LW, UK
fSchool of Ecology and Environmental Science, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan, 450001, PR China
*Corresponding author.
Abstract
Surface plasmon resonance approach is a highly useful option to offer optical and label-free detection of target bioanalytes with numerous advantages (e.g., low-cost fabrication and analysis, appreciable sensitivity, label-free detection, and outstanding accuracy). As such, it allows early diagnosis of cancer biomarkers to monitor tumor progression and to prevent the recurrence of oncogenic tumors. This work highlights the recent progress in SPR biosensing technology for the diagnosis of various cancer types (e.g., lung, breast, prostate, and ovarian). Further, the performance of various SPR biosensors is also evaluated in terms of the basic quality assurance criteria (e.g., limit of detection (LOD), selectivity, sensor response time, and reusability). Finally, the limitations and future challenges associated with SPR biosensors are also discussed with respect to cancer biomarker detection.
Keywords : Biosensing, Cancer, Nanomaterials, Surface plasmon resonance
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