한빛사 논문
Yoonseok Park1,2,*, Kyeongha Kwon3,*, Sung Soo Kwak1,2,4,*, Da Som Yang1,2,*, Jean Won Kwak1,2,5,*, Haiwen Luan1,2,5,6, Ted S. Chung1,2,7, Keum San Chun8, Jong Uk Kim1,9, Hokyung Jang10, Hanjun Ryu1,2, Hyoyong Jeong1,2, Sang Min Won11, Youn J. Kang1,2, Michael Zhang2, David Pontes2, Brianna R. Kampmeier2, Seon Hee Seo1,12, Jeffrey Zhao13, Inhwa Jung14, Yonggang Huang1,2,5,6,15, Shuai Xu1,2,13,† and John A. Rogers1,2,5,7,14,16,†
1Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.
2Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA.
3School of Electrical Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea.
4School of Advanced Materials Science and Engineering, Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.
5Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA.
6Department of Civil and Environmental Engineering, Northwestern University, Evanston, IL 60208, USA.
7Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.
8Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX 78712, USA.
9School of Chemical Engineering, Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.
10Department of Electrical and Computer Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
11Department of Electrical and Computer Engineering, Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.
12Nano Hybrid Technology Research Center, Creative and Fundamental Research Division, Korea Electrotechnology Research Institute (KERI), Changwon 51543, Republic of Korea.
13Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
14Department of Mechanical Engineering, Kyung Hee University, Yongin 17104, Republic of Korea.
15Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.
16Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
†Corresponding author.
*These authors contributed equally to this work.
Abstract
Therapeutic compression garments (TCGs) are key tools for the management of a wide range of vascular lower extremity conditions. Proper use of TCGs involves application of a minimum and consistent pressure across the lower extremities for extended periods of time. Slight changes in the characteristics of the fabric and the mechanical properties of the tissues lead to requirements for frequent measurements and corresponding adjustments of the applied pressure. Existing sensors are not sufficiently small, thin, or flexible for practical use in this context, and they also demand cumbersome, hard-wired interfaces for data acquisition. Here, we introduce a flexible, wireless monitoring system for tracking both temperature and pressure at the interface between the skin and the TCGs. Detailed studies of the materials and engineering aspects of these devices, together with clinical pilot trials on a range of patients with different pathologies, establish the technical foundations and measurement capabilities.
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