한빛사 논문
고려대학교, Shenzhen University
Yingwei Wanga,b, Meng Qiub, Miae Wona, Eugeine Jungc, Taojian Fanb, Ni Xied, Sung-Gil Chic,*, Han Zhangb,*, Jong Seung Kima,*
a Department of Chemistry, Korea University, Seoul 02841, Republic of Korea
b Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Electronic Science and Technology and College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, People’s Republic of China
c Department of Life Sciences, Korea University, Seoul 02841, Republic of Korea
d Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University and Collaborative Innovation Center for Optoelectronic Science and Technology of Shenzhen University, Shenzhen 518060, PR China
*Corresponding authors
Abstract
2D materials (e.g., graphene, graphene analogues), with unique physical and chemical properties, shows intriguing potential for the realization of versatile biomedical applications. Tremendous attention has been attracted on 2D material based nanocarriers, which play a crucial role in therapeutic drug, gene, and biomedical agent delivery for cancer theranostics. This review provides an up-to-date review on the development of nanocarriers based on 2D materials beyond graphene, including basic and emerging synthesis methods, the catalog of 2D material-based nanocarriers, biosafety, surface functional engineering, the realization of stimuli-responsive controllable release and biomedical applications. Among the properties and performance to be summarized, there is particular focus on nanocarriers loading capability, biosafety, and therapy efficiency and so on. Finally, by addressing major issues and challenges, some prospects for future directions in this area are provided.
Keywords : 2D material; Drug delivery; Nanomaterial; Cancer therapy; Nanocarrier
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