한빛사 논문
한국파스퇴르연구소
Alexander König1,a, Thoa Thi Than1,a, Daniel Todt2, Seung Kew Yoon3, Jochen Steinmann4, Eike Steinmann2,*, Marc P. Windisch1,*
1 Applied Molecular Virology Laboratory, Unmet Medical Needs Division, Institut Pasteur Korea, 696 Sampyung-dong, Bundang-gu, Seongnam-si, 13488, Gyeonggi-do, South Korea
2 Ruhr University Bochum, Faculty of Medicine, Department for Molecular and Medical Virology, 44801 Bochum, Germany
3 Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, 06591, Seoul, South Korea
4 Dr. Brill + Partner GmbH Institute for Hygiene and Microbiology, 28259 Bremen, Germany
aAlexander König and Thoa Thi Than contributed equally to this work.
*Corresponding authors at : Eike Steinmann, Marc P. Windisch
Abstract
To the Editor:
Hepatitis B virus (HBV) is a severe global health burden, with approximately 2 billion infected individuals and more than 250 million carriers worldwide. Despite the availability of vaccines and therapeutics, chronic hepatitis B remains incurable. The virus is highly contagious and can circulate with 108 to 1010 infectious particles in a patient’s blood. Because HBV has a very low minimal infectious dose of only 10 genomes, the transmission from only trace amounts of blood pose a serious risk for infection. [1] This risk highlights the importance of implementing guidelines for HBV prevention and management in infection control systems, such as thermal disinfection of medical devices.
Keywords : Hepatitis B virus; thermostability; inactivation; infectivity
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