Indoor Exposure and Sensitization to Formaldehyde among Inner-City Children with Increased Risk of Asthma and Rhinitis
 Authors and Affiliations
 Authors and Affiliations
Dong Keon Yon, MD,1 Sohyun Hwang, PhD,2,3 Seung Won Lee, MD, PhD,1 Hye Mi Jee, MD,1 Youn Ho Sheen, MD, PhD,4 Jeong Hee Kim, MD, PhD,5 Dae Hyun Lim, MD, PhD,5 Man Yong Han, MD,1*
1 Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea
2 Department of Biomedical Science, CHA University College of Life Science, Seongnam, Republic of Korea
3 Department of Medical Statistics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea
4 Department of Pediatrics, CHA Gangnam Medical Center, CHA University School of Medicine, Seoul, Republic of Korea
5 Department of Pediatrics, Inha University Hospital, Inha University School of Medicine, Incheon, Republic of Korea
*Corresponding authors : Professor Man Yong Han, MD
Department of Pediatrics, CHA University School of Medicine, 351 Yatap-dong, Bundanggu, Seongnam, Gyeonggi-do, 463-712, Republic of Korea
Abstract To the editor
Indoor exposure to formaldehyde is a major health concern, especially for school-age children who spend most of their time indoors(1), because at room temperature, formaldehyde evaporates from wood-based products, flooring materials, paints, fabrics, cosmetics, cleaning products, and air fresheners. Evidence supporting a link of indoor formaldehyde exposure with asthma and rhinitis is controversial, in that previous studies have reported a negative association,(2) no association,(3) and a positive association.(4) Furthermore, few studies have examined the major formaldehyde metabolite (thiazolidine-4-carboxylic acid [TZCA]), or sensitization to formaldehyde in subjects with asthma and/or rhinitis.
Keywords: foramaldehyde; asthma; allergic rhinitis
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