한빛사 논문
Seung Seog Han1, 7, Myoung Shin Kim2, 7, Woohyung Lim3, Gyeong Hun Park4, Ilwoo Park5, Sung Eun Chang6,*
1 I Dermatology Clinic, Seoul, Korea
2 Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea
3 SK Telecom, Human Machine Interface Technology Laboratory, Seoul, Korea
4 Department of Dermatology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Dongtan, Korea
5 Department of Radiology, Chonnam National University Medical School and Hospital, Gwangju, Korea
6 Department of Dermatology, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea
7 These authors contributed equally to this work.
*Correspondence: Sung Eun Chang, Department of Dermatology, Asan Medical Center, Ulsan University College of Medicine, 88, OLYMPIC-RO 43-GIL Songpa-gu, Seoul, 05505, Korea
Abstract
We tested the use of a deep learning algorithm to classify the clinical images of 12 skin diseases?basal cell carcinoma, squamous cell carcinoma, intraepithelial carcinoma, actinic keratosis, seborrheic keratosis, malignant melanoma, melanocytic nevus, lentigo, pyogenic granuloma, hemangioma, dermatofibroma, and wart. The convolutional neural network (Microsoft ResNet-152 model; Microsoft Research Asia, Beijing, China) was fine-tuned with images from the training portion of the Asan dataset, MED-NODE dataset, and atlas site images (19,398 images in total). The trained model was validated with the testing portion of the Asan, Hallym and Edinburgh datasets. With the Asan dataset, the area under the curve for the diagnosis of basal cell carcinoma, squamous cell carcinoma, intraepithelial carcinoma, and melanoma was 0.96 ± 0.01, 0.83 ± 0.01, 0.82 ± 0.02, and 0.96 ± 0.00, respectively. With the Edinburgh dataset, the area under the curve for the corresponding diseases was 0.90 ± 0.01, 0.91 ± 0.01, 0.83 ± 0.01, and 0.88 ± 0.01, respectively. With the Hallym dataset, the sensitivity for basal cell carcinoma diagnosis was 87.1% ± 6.0%. The tested algorithm performance with 480 Asan and Edinburgh images was comparable to that of 16 dermatologists. To improve the performance of convolutional neural network, additional images with a broader range of ages and ethnicities should be collected.
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