Dae-Kyum Kim1,†,‡, Jaewook Lee1,†,‡, Sae Rom Kim1,‡, Dong-Sic Choi1,‡, Yae Jin Yoon2,‡, Ji Hyun Kim1,‡, Gyeongyun Go1,‡, Dinh Nhung1,‡, Kahye Hong1,‡, Su Chul Jang1,‡, Si-Hyun Kim1,‡, Kyong-Su Park1,‡, Oh Youn Kim1,‡, Hyun Taek Park1,‡, Ji Hye Seo1,‡, Elena Aikawa3, Monika Baj-Krzyworzeka4, Bas W. M. van Balkom5, Mattias Belting6, Lionel Blanc7, Vincent Bond8, Antonella Bongiovanni9, Francesc E. Borràs10, Luc Buée11, Edit I. Buzás12, Lesley Cheng13, Aled Clayton14, Emanuele Cocucci15, Charles S. Dela Cruz16, Dominic M. Desiderio17, Dolores Di Vizio18, Karin Ekström19,20, Juan M. Falcon-Perez21, Chris Gardiner22, Bernd Giebel23, David W. Greening24, Julia Christina Gross25, Dwijendra Gupta26, An Hendrix27, Andrew F. Hill13, Michelle M. Hill28, Esther Nolte-’t Hoen29, Do Won Hwang30, Jameel Inal31, Medicharla V. Jagannadham32, Muthuvel Jayachandran33, Young-Koo Jee34, Malene Jørgensen35, Kwang Pyo Kim36, Yoon-Keun Kim37, Thomas Kislinger38, Cecilia La¨sser39, Dong Soo Lee30, Hakmo Lee40, Johannes van Leeuwen41, Thomas Lener42,43, Ming-Lin Liu44,45, Jan Lo¨ tvall39, Antonio Marcilla46, Suresh Mathivanan24, Andreas Mo¨ ller47, Jess Morhayim41, Franc¸ois Mullier48,49, Irina Nazarenko50, Rienk Nieuwland51, Diana N. Nunes52, Ken Pang53,54, Jaesung Park55, Tushar Patel56, Gabriella Pocsfalvi57, Hernando del Portillo58, Ulrich Putz59, Marcel I. Ramirez60, Marcio L. Rodrigues61,62, Tae-Young Roh1,2, Felix Royo21, Susmita Sahoo63, Raymond Schiffelers64, Shivani Sharma65, Pia Siljander66, Richard J. Simpson24, Carolina Soekmadji67, Philip Stahl68, Allan Stensballe69, Ewa Stępień70, Hidetoshi Tahara71, Arne Trummer72, Hadi Valadi73, Laura J. Vella74, Sun Nyunt Wai75, Kenneth Witwer76, María Yáñez-Mó 77, Hyewon Youn30, Reinhard Zeidler78 and Yong Song Gho1,‡,*
1Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea, 2Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, Republic of Korea, 3Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA, 4Department of Clinical Immunology, Polish-American Institute of Paediatrics, Jagiellonian University Medical College, Cracow, Poland, 5Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands, 6Section of Oncology, Department of Clinical Sciences, Lund University, Lund, Sweden, 7The Feinstein Institute for Medical Research, Manhasset, NY, USA, 8Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, Atlanta, GA, USA, 9Institute of Biomedicine and Molecular Immunology (IBIM), National Research Council (CNR), Palermo, Italy, 10Innovation in Vesicles and Cells for Application in Therapy, Germans Trias i Pujol Research Institute, Germans Trias i Pujol University Hospital, Badalona, Spain, 11INSERM, UMR837 JEAN-PIERRE Aubert Research Centre, Lille, France, 12Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary, 13Department of Biochemistry and Molecular Biology, BIO21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia, 14Institute of Cancer & Genetics, School of Medicine, Velindre Cancer Centre, Cardiff University, Cardiff, UK, 15Program in Cellular and Molecular Medicine at Boston Children’s Hospital and Department of Cell Biology, Harvard Medical School, Boston, MA, USA, 16Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA, 17Department of Neurology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA, 18Cancer Biology Program, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA, 19Department of Biomaterials, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, 20BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, Gothenburg, Sweden, 21Metabolomics Unit, CIC bioGUNE, CIBERehd, IKERBASQUE Research Foundation, Technology Park of Bizkaia, Derio, Bizkaia, Spain, 22Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, University of Oxford, Oxford, UK, 23Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany, 24La Trobe Institute for Molecular Science (LIMS), La Trobe University, Melbourne, VIC, Australia, 25Division of Signaling and Functional Genomics, German Cancer Research Center, Heidelberg, Germany, 26Jai Prakash University, Chapra, Bihar, India, 27Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium, 28The University of Queensland Diamantina Institute, Translational Research Institute, The University of Queensland, Brisbane, QLD, Australia, 29Department of Biochemistry & Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands, 30Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, 31Cellular and Molecular Immunology Research Centre, Faculty of Life Sciences and Computing, London Metropolitan University, London, UK, 32CSIR-Centre for Cellular and Molecular Biology, Hyderabad, Andhra Pradesh, India, 33Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA, 34Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Republic of Korea, 35Department of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark, 36Department of Applied Chemistry, Kyung Hee University, Yongin, Republic of Korea, 37Ewha Womans University Medical Center, Seoul, Republic of Korea, 38Ontario Cancer Institute, Toronto, ON, Canada, 39Krefting Research Centre, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 40Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea, 41Department of Internal Medicine, Erasmus University Rotterdam Medical Centre, Rotterdam, The Netherlands, 42Department of Blood Group Serology and Transfusion Medicine, University Hospital of Salzburg, Paracelsus Medical University, Salzburg, Austria, 43Spinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University, Salzburg, Austria, 44Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA, 45Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA, 46Área de Parasitología, Departamento de Biología Celular y Parasitología, Universitat de València, Burjassot, Valencia, Spain, 47Tumour Microenvironment Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia, 48Hematology Laboratory, NARILIS, Namur Thrombosis and Hemostasis Center (NTHC), CHU Dinant Godinne UCL Namur, Universite´ Catholique de Louvain, Belgium, 49Department of Pharmacy, NARILIS, Namur Thrombosis and Hemostasis Center (NTHC), University of Namur, Naumr, Belgium, 50Institute of Environmental Health Sciences and Hospital Infection Control, Medical Center-University of Freiburg, Freiburg, Germany, 51Department of Clinical Chemistry, Academic Medical Center, Amsterdam, The Netherlands, 52Laboratory of Medical Genomics, A.C. Camargo Cancer Center, Sa? o Paulo, Brazil, 53Inflammation Division, The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia, 54Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia, 55Department of Mechanical Engineering, Pohang University of Science and Technology, Pohang, Republic of Korea, 56Departments of Transplantation and Cancer Biology, Mayo Clinic, Jacksonville, FL, USA, 57Mass Spectrometry and Proteomics, Institute of Biosciences and Bioresources, National Research Council of Italy, Naples, Italy, 58ICREA, Barcelona Centre for International Health Research, Barcelona, Spain, 59The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC, Australia, 60Laboratory of Molecular Biology of Parasites and Vectors, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil, 61Paulo de Góes Microbiology Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil, 62Centre for Technological Development in Health (CDTS), Oswaldo Cruz Foundation, Rio de Janeiro, Brazil, 63Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA, 64Department of Clinical Chemistry and Hematology, University Medical Center Utrecht, Utrecht, The Netherlands, 65California Nanosystems Institute, University of California Los Angeles, Los Angeles, CA, USA, 66Division of Biochemistry and Biotechnology, Department of Biosciences, University of Helsinki, Helsinki, Finland, 67Australian Prostate Cancer Research Centre-Queensland, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD, Australia, 68Department of Cell Biology and Physiology, Washington University School of Medicine, Saint Louis, MO, USA, 69Department of Health Science and Technology, Aalborg University, Aalborg, Denmark, 70Department of Medical Physics, Jagiellonian University, Cracow, Poland, 71Department of Cellular and Molecular Biology, Graduate School of Biomedical Science, Hiroshima University, Hiroshima, Japan, 72Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany, 73Department of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 74Ludwig Institute for Cancer Research Melbourne, Austin Hospital, Heidelberg, VIC, Australia, 75Department of Molecular Biology, Umeå University, Umeå, Sweden, 76Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA, 77Unidad de Investigación, Hospital Santa Cristina, Instituto de Investigación Sanitaria Princesa, Madrid, Spain, 78Department of Otorhinolaryngology and Research Group Gene Vectors, University of Muenchen, HelmholtzZentrum München, Munich, Germany
*To whom correspondence should be addressed.
†The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors. Associate Editor: Janet Kelso
‡Only these authors are not listed alphabetically by their last name