Eun-Sook Lee1,a, Hansol Shin2,a, Jung-Min Seo2, Young-Do Nam1, Byung-Hoo Lee2,* and Dong-Ho Seo1, *
1Research Group of Gut Microbiome, Korea Food Research Institute, Wanju 55365, Republic of Korea
2Department of Food Science and Biotechnology, College of BioNano Technology, Gachon University, Seongnam 13120, Republic of Korea
aThese authors contributed equally.
*Corresponding authors: Dong-Ho Seo, Byung-Hoo Lee
Abstract
Starch digestion in the gastrointestinal tract has different properties depending on its botanical source. In this study, corn, wheat, rice, and potato starches were used to test the digestion properties of mammalian mucosal α-glucosidase in an in vitro assay, and their physiological effects were investigated in male C57BL/6 mice. The results clearly demonstrated that potato starch caused the lowest rates of glucose generation, suggesting that it can attenuate the postprandial glucose spike. Interestingly, a potato starch-based diet caused significantly (P<0.05) lower weight gain and fat accumulation compared to diets based on other starches, through increased insulin sensitivity. This result suggests that potato starch-based products can be used to regulate postprandial blood glucose levels, aiding in the control of metabolic diseases.
Keywords: potato starch; glucose delivery; starch digestion; insulin sensitivity; fat accumulation