[DEBUG-WINDOW 처리영역 보기]
즐겨찾기  |  뉴스레터  |  오늘의 정보  |  e브릭몰e브릭몰 sale 회원가입   로그인
BRIC홈 농수식품
검색광고안내
시마즈(SHIMADZU) 제작소 탐방기 - 1편
스폰서배너광고 안내  배너1 배너2 배너3 배너4
과학으로 본 코로나19 (COVID-19)
전체보기 농림성과 식품성과 인터뷰
Cheng Chi
Cheng Chi (Cheng Chi) 저자 이메일 보기
서울대학교 수의과대학
저자CV 보기
156 KB
 
조회 1307  인쇄하기 주소복사 트위터 공유 페이스북 공유 
Effects of algal toxin okadaic acid on the non-specific immune and antioxidant response of bay scallop (Argopecten irradians)

Cheng Chi , Sib Sankar Giri , Jin Woo Jun , Hyoun Joong Kim, Sang Wha Kim, Saekil Yun, Se Chang Park*

Laboratory of Aquatic Biomedicine, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 151742, South Korea

*Corresponding author: Se Chang Park

Abstract
Okadaic acid (OA) is produced by dinoflagellates during harmful algal blooms and is a diarrhetic shellfish-poisoning (DSP) toxin. This toxin is particularly problematic for bivalves that are cultured for human consumption. This study aimed to reveal the effects of exposure to OA on the non-specific immune responses of bay scallop, Argopecten irradians. Various immunological parameters (superoxide dismutase (SOD), acid phosphatase (ACP), alkaline phosphatase (ALP), lysozyme activities, and total protein level) were assessed in the hemolymph of bay scallops at 3, 6, 12, 24, and 48 h post-exposure (hpe) to different concentrations (50, 100, and 500 nM) of OA. Moreover, the expression of immune system-related genes (MnSOD, PrxV, PGRP, and BD) was also measured. Results showed that SOD and ACP activities were decreased between 12 and 48 hpe. The ALP, lysozyme activities, and total protein levels were also modulated after exposure to different concentrations of OA. The expression of immune-system-related genes was also assessed at different time points during the exposure period. Overall, our results suggest that the exposure to OA had negative effects on the antioxidant and non-specific immune responses, and even disrupted the metabolism of bay scallops, making them more vulnerable to environmental stress-inducing agents; they provide a better understanding of the response status of bivalves against DSP toxins.

Keywords : Okadaic acid; Harmful algal blooms; Bay scallop; Argopecten irradians; Non-specific immune response; Antioxidant response

논문정보
- 형식: Research article
- 게재일: 2017년 03월 (BRIC 등록일 2017-03-23)
- 연구진: 국내연구진 태극기
- 분야: Immunology, Marine_Biology, Veterinary_Science
  댓글 0
등록
 
목록
한국벡크만쿨터
외부관련링크
Google scholar (by Cheng Chi)
Pubmed (by Cheng Chi)
프리미엄 Bio일정 Bio일정 프리미엄 안내
대구경북과학기술원 (DGIST) 뇌·인지과학전공 온라인 전공설명회 개최
 
위로가기
농수식품 홈  |  농수식품 문의 및 제안
 |  BRIC소개  |  이용안내  |  이용약관  |  개인정보처리방침  |  이메일무단수집거부
Copyright © BRIC. All rights reserved.  |  문의 member@ibric.org
트위터 트위터    페이스북 페이스북   유튜브 유튜브    RSS서비스 RSS
에펜도르프코리아 광고