한빛사 논문
Abstract
Jin-sil Choi,† Young-wook Jun,† Soo-In Yeon,‡ Hyoung Chan Kim,§ Jeon-Soo Shin,*,‡ and Jinwoo Cheon*,†
†Department of Chemistry, Yonsei UniVersity, Seoul 120-749, Korea, ‡Department of Microbiology, College of Medicine, Yonsei UniVersity, Seoul 120-752, Korea, and §National Fusion Research Center, Korea Basic Science Institute (KBSI), Daejeon 305-333, Korea
*Corresponding authors
Abstract
Hybrid nanoparticles are of significant interest primarily because of their innate multifunctional capabilities. These capabilities can be exploited when hybrid nanoparticles are used for applications in the biomedical sciences in particular, where they are utilized as multimodal nanoplatforms for sensing, imaging, and therapy of biological targets. However, the realization of their biomedical applications has been difficult, in part because of a lack of high quality hybrid nanoparticles which possess high aqueous colloidal stability and biocompatibility while retaining their multifunctionalities. Here, we present the development of inorganic heterodimer nanoparticles of FePt-Au with multifunctional capabilities including catalytic growth effects, magnetic resonance (MR) contrast effects, optical signal enhancing properties, and high colloidal stability and biocompatibility. Their multimodal capabilities for biological detection are demonstrated through their utilizations in the patterned biochip based detection of avidin?biotin interaction as well as in molecular MR imaging of neuroblastoma cells.
논문정보
관련 링크
연구자 ID
관련분야 연구자보기
소속기관 논문보기
관련분야 논문보기
해당논문 저자보기