한빛사 논문
충남대학교
Abstract
Suyeob Kim1, Jung-Mi Moon2, Joon Sig Choi3,*, Woo Kyung Cho4,* and Sung Min Kang1,*
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1Department of Marine Biomaterialsand Aquaculture, Pukyong National University, Busan, Republic of Korea
2Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon, Republic of Korea
3Department of Biochemistry, Chungnam National University, Daejeon, Republic of Korea
4Department of Chemistry, Chungnam National University, Daejeon, Republic of Korea
*Corresponding author : Joon Sig Choi, Woo Kyung Cho, Sung Min Kang
S.K. and J.-M.M. contributed equally to this work.
Abstract
The exceptional mechanical properties of the byssus-the fibrous holdfast of mussels that provides underwater adhesion-have potential applications in medicine and technology. The catechol-Fe3+-catechol interaction underlies the unique properties of mussel byssus and has emerged as a tool for developing functional hybrid materials such as pH-responsive, self-healing gels. Herein, the construction of functional alginate (Alg) film on a solid substrate inspired by mussel byssus is reported. The approach consists of spin-coating-assisted deposition of Alg catechols onto a solid substrate and their subsequent crosslinking via catechol-Fe3+catechol interactions. This yields robust and multilayered Alg films that are resistant to protein adsorption and suppress bacterial adhesion. This method can be used to create antibacterial films for coating implanted medical devices.
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