Oh Seok Kwon1,†, Seung Hwan Lee2,†, Seon Joo Park1, Ji Hyun An1, Hyun Seok Song2, Taejoon Kim3, Joon Hak Oh4, Joonwon Bae5, Hyeonseok Yoon3, Tai Hyun Park2,*, Jyongsik Jang1,*
1 World Class University program of Chemical, Convergence for Energy & Environment, School of Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Republic of Korea
2 School of Chemical and Biological Engineering, Bio-MAX Institute, Seoul National University, Seoul 151-744, Republic of Korea
3 Alan G. MacDiarmid Energy Research Institute, Department of Polymer and Fiber System Engineering, Chonnam National University, Gwangju 500-757, South Korea
4 School of Nano-Bioscience and Chemical Engineering, KIER-UNIST Advanced Center for Energy, Low Dimensional Carbon Materials Center, Ulsan National Institute of Science and Technology, Ulsan 689-798, Republic of Korea
5 Department of Applied Chemistry Dongduk Women's University, Seongbuk-gu, Seoul 136-714, Republic of Korea
† These authors contributed equally to this work.
*To whom correspondence should be addressed.
Large-scale FET-type graphene micropatten (GM) nano-biohybrid-based immunosensor (GMNS) is fabricated in a controlled fashion to detect human immunodeficiency virus 2 antibody. Flexible GMNS shows a highly sensitive response and excellent mechanical bendability. The flexible GMNS in fluidic systems also has a stable response. This is the first experimental demonstration of a large-scale flexible fluidic FET-type immunoassay based on GM nano-biohybrids.
Keywords: graphene; immunoassay; nano-biohybrids; flexible electronics; microfluidics