한빛사 논문
연세대학교
Abstract
Jae-Hyun Lee1†, Eun Sook Kim 2‡, Mi Hyeon Cho 1, Mina Son 2, Soo-In Yeon 2, Jeon-Soo Shin, Prof. 2 *, Jinwoo Cheon, Prof. 1 *
1Department of Chemistry, Yonsei University, Seoul 120-749 (Korea), Fax: (+82) 2-364-7050
2Department of Microbiology, Institute for Immunology and Immunological Diseases, College of Medicine, Yonsei University, Seoul 120-752 (Korea), Fax: (+82) 2-392-7088
*Correspondence to Jeon-Soo Shin, 2Department of Microbiology, Institute for Immunology and Immunological Diseases, College of Medicine, Yonsei University, Seoul 120-752 (Korea), Fax: (+82) 2-392-7088
*Correspondence to Jinwoo Cheon, 1Department of Chemistry, Yonsei University, Seoul 120-749 (Korea), Fax: (+82) 2-364-7050
†We thank Prof. Gou Young Koh (KAIST) for recombinant Ang2 and his kind support. This research was supported by the NRL (M10600000255), Creative Research Institute (2010-0018286), WCU program, NBIT (Grant K20716000001-07A0400-00110), Nanomedical NCRC (R15-2004-024-00000-0), LG Yonam Foundation, 2nd stage BK21 for Chemistry and Medical Sciences of Yonsei University, the Korean Health 21 R&D Project (A050260) of the Ministry of Health & Welfare, the KRF Grant (KRF-2007-2-E00154), and Mid-career Researcher Program (2009-0081001) through NRF by the MEST.
‡These authors contributed equally to this work.
Funded by:
NRL; Grant Number: M10600000255
Creative Research Institute; Grant Number: 2010-0018286
WCU program
NBIT; Grant Number: K20716000001-07A0400-00110
Nanomedical NCRC; Grant Number: R15-2004-024-00000-0
LG Yonam Foundation
Korean Health 21 R&D Project; Grant Number: A050260
Ministry of Health & Welfare
KRF Grant; Grant Number: KRF-2007-2-E00154, 2009-0081001
NRF
MEST
Keywords
angiogenesis, cellular signaling, magnetic properties, nanoparticles, receptors
Abstract
Magnetic attraction: Artificial control of cell activities is achieved by nanoscale magneto-activated cellular signaling (N-MACS), in which magnetic nanoparticles are selectively linked to cell surface receptors and aggregated by an external magnetic field. Such mechanocellular activation induces downstream cell signaling and initiates tubulogenesis in the preangiogenesis stage of endothelial cells (see picture).
논문정보
관련 링크
연구자 키워드
연구자 ID
관련분야 연구자보기
소속기관 논문보기
관련분야 논문보기
해당논문 저자보기