한빛사 논문
Abstract
Long-Hao Lia, Young-Min Konga, Hae-Won Kima, Young-Woon Kima, Hyoun-Ee Kim a, Seong-Joo Heob and Jai-Young Koakb
a School of Materials Science and Engineering, Seoul National University, Seoul, 151-742, South Korea
b Department of Prosthodontics, College of Dentistry, Seoul National University, Seoul, South Korea
Received 11 May 2003; accepted 4 September 2003. ; Available online 18 November 2003.
Abstract
The surface of a titanium (Ti) implant was modified by micro-arc oxidation (MAO) treatment. A porous layer was formed on the Ti surface after the oxidation treatment. The phase and morphology of the oxide layer were dependent on the voltage applied during the oxidation treatment. With increasing voltage, the roughness and thickness of the film increased and the TiO2 phase changed from anatase to rutile. During the MAO treatment, Ca and P ions were incorporated into the oxide layer. The in vitro cell responses of the specimen were also dependant on the oxidation conditions. With increasing voltage, the ALP activity increased, while the cell proliferation rate decreased. Preliminary in vivo tests of the MAO-treated specimens on rabbits showed a considerable improvement in their osseointegration capability as compared to the pure titanium implant.
Author Keywords: Titanium; Oxidation; Biocompatibility; In vitro; Osseointegration; In vivo
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