한빛사 논문
Abstract
Jaemoon Yang1 2, Jaewon Lee 2, Jinyoung Kang 2, Seung Jae Oh1 3, Hyun-Ju Ko 1, Joo-Hiuk Son 4, Kwangyeol Lee 5, Jin-Suck Suh1, Yong-Min Huh1 *, Seungjoo Haam2 *
1Department of Radiology Yonsei University Seoul, 120-752 (Republic of Korea)
2Department of Chemical and Biomolecular Engineering Yonsei University Seoul, 120-749 (Republic of Korea)
3Brain Korea 21 Project for Medical Science Yonsei University Seoul, 120-749 (Republic of Korea)
4Department of Physics University of Seoul Seoul, 130-743 (Republic of Korea)
5Department of Chemistry, Korea University Seoul 136-701 (Republic of Korea)
email: Yong-Min Huh, Seungjoo Haam
*Correspondence to Yong-Min Huh, Department of Radiology Yonsei University Seoul, 120-752 (Republic of Korea).
*Correspondence to Seungjoo Haam, Department of Chemical and Biomolecular Engineering Yonsei University Seoul, 120-749 (Republic of Korea).
Funded by:
Korea government; Grant Number: M10755020001-07N5502-00110, R15- 2004-024-00000-0, 2007-04717
Korea Health 21 R&D Project
Ministry of Health &Welfare; Grant Number: A085136
Yonsei University College of Medicine; Grant Number: 6-2008-0223
Republic of Korea
Keywords
cancer, drug load, gold nanoshells, near infrared, polymer
Abstract
Near-infrared-light-sensitive multifunctional smart drug-loaded polymer gold nanoshells are fabricated as advanced prototypes, composed of chemotherapeutic agents (therapeutic antibody and anticancer drug-loaded polymeric nanoparticles) for systemic chemotherapy of human epithelial cancer and a polymer-based gold nanoshell for localized photothermal treatment by NIR light.
Received: 30 January 2009; Revised: 17 April 2009
Digital Object Identifier (DOI)
10.1002/adma.200900334
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