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'toxicology' 에 대한 통합검색결과 181건입니다.

한빛사181건

최신순
관련도순

Quantitative Assessment of Particulate Matter Biodistribution Using 14C-Nanotracing and Accelerator Mass Spectrometry
- Environ. Sci. Technol. Jan 13 2026, | https://doi.org/10.1021/acs.est.5c11834
- 2026.01
- 바이오·의료융합
A Biomarker-Driven Ovary-Endometrium Organ-on-a-Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicit
- Adv. Sci. Jan 15 2026, | https://doi.org/10.1002/advs.202511098
- 2026.01
- 바이오·의료융합
- 정원우(Wake Forest Institute for Regenerative Medicine)
- 이상진(Wake Forest School of Medicine)
The effect of stiffness on cell behavior and drug resistance in patient-derived breast cancer organoids
- Acta Biomater. Dec 13 2025, S1742-7061(25)00933-X | https://doi.org/10.1016/j.actbio.2025.12.026
- 2025.12
- 바이오·의료융합
조이시 산무게아

한국원자력의학원

Our study examined whether very small plastic particles, specifically 20 to 50 nm polystyrene nanoplastics, can enter the body through the skin. Using a 3D human epidermal model and a chronic dermal exposure mouse model, we found that even low cosmetic-like doses activated inflammation and skin-aging pathways, with hundreds of genes altered and clear thinning of the epidermis.
- J. Hazard. Mater.
- 2025.11.26
이유빈

국가독성과학연구소

본 논문은 면역세포, 간세포, 혈관세포를 함께 배양하여 실제 인체와 유사한 환경을 재현하고, 약물이나 외부 자극으로 인한 면역 매개 간 독성 예측을 위한 모델을 제시한 연구입니다. 저는 과거 생체재료 기반 조직공학 연구에서 익혔던 생체친화적 Gel-MA 하이드로젤과 3D 바이오프린팅 기술을 이번 연구에 생체모사, 표준화 관점에서 접목했습니다.
- Chem. Eng. J.
- 2025.09.26
- 박경서(University of Gothenburg)
STING Agonist Drug Delivery by Bacterial Extracellular Vesicles Induces Synergistic Immuno-Oncology Responses and Efficient Inhibition of Tumour Growt
- J. Extracell. Vesicles Jul 2025, 14 (7) | https://doi.org/10.1002/jev2.70117
- 2025.07
- 의약학
- 김동현(서울시립대학교)
  Interview
- 최진희(서울시립대학교)
Identification of developmental and reproductive toxicity of biocides in consumer products using ToxCast bioassays data and machine learning models
- Environ. Int. Jun 18 2025, 202 S0160-4120(25)00372-1 | https://doi.org/10.1016/j.envint.2025.109621
- 2025.06
- 바이오·의료융합
이홍

고려대학교 의과대학

환경독성학은 산업화의 진전에 따라 등장한 응용과학 분야로, 초기에는 고용량 노출에 따른 급성 독성 평가에 중점을 두었으나 최근에는 환경성 노출인자의 저농도 만성 노출이 유기체에 미치는 누적적 전신 영향에 대한 관심이 급격히 증가하고 있습니다. 특히, 생활환경 속 수많은 유해물질들이 장기적으로 신경계, 면역계, 호흡기계, 생식계 등 다양한 생리적 체계에 미치는 만성 독성의 기전 규명이 중요한 연구 흐름으로 자리잡고 있습니다.
- J. Hazard. Mater.
- 2025.05.07
- 윤정열(The University of Arizona)
A comparative review of organ-on-a-chip technologies for micro- and nanoplastics versus other environmental toxicants
- Biosens. Bioelectron. Apr 12 2025, 282 S0956-5663(25)00346-X | https://doi.org/10.1016/j.bios.2025.117472
- 2025.04
Kojo Eghan

안전성평가연구소

Our study focuses on evaluating the neurotoxic effects of 2-ethylhexanol, a chemical widely used in industrial applications, including plastic production, solvents, and fragrances. Despite its widespread presence in the environment, its potential impact on neurodevelopment has not been fully explored.
- J. Hazard. Mater.
- 2025.02.11
- 김세정(University of Pennsylvania)
- 허동은(University of Pennsylvania)
A Bioengineered Model of the Human Cornea for Preclinical Assessment of Human Ocular Exposure to Environmental Toxicants
- Adv. Healthc. Mater. Jan 21 2025, | https://doi.org/10.1002/adhm.202402408
- 2025.01
- 바이오·의료융합
Therapeutic effect of novel drug candidate, PRG-N-01, on NF2 syndrome-related tumor
- Neuro-Oncology Dec 28 2024, noae282 | https://doi.org/10.1093/neuonc/noae282
- 2024.12
- 생명과학
Applying newly suggested simultaneous analysis of metabolomics and lipidomics into perfluorooctanesulfonate-derived neurotoxicity mechanism in zebrafi
- J. Hazard. Mater. Nov 28 2024, 484 S0304-3894(24)03293-X | https://doi.org/10.1016/j.jhazmat.2024.136712
- 2024.11
- 생명과학
- 유민희(안전성평가연구소)
- 김용범(안전성평가연구소)
Potential of 6‘?hydroxy justicidin B from Justicia procumbens as a therapeutic agent against coronavirus disease 2019
- Phytomedicine Aug 31 2024, 134 S0944-7113(24)00671-8 | https://doi.org/10.1016/j.phymed.2024.156014
- 2024.08
- 의약학
- 이효진(University of Ottawa)
Empirical Characterization of False Discovery Rates of Differentially Expressed Genes and Transcriptomic Benchmark Concentrations in Zebrafish Embryos
- Environ. Sci. Technol. Mar 26 2024, | https://doi.org/10.1021/acs.est.3c10543
- 2024.03
- 생명과학
Human chemically-derived hepatic progenitors (hCdHs) as a source of liver organoid generation: Application in regenerative medicine, disease modeling,
- Biomaterials Available online 20 October 2023, 122360 | https://doi.org/10.1016/j.biomaterials.2023.122360
- 2023.10
- 생명과학
Soraya Salas-Silva

한양대학교

We developed 3D liver organoids for modeling tissue function and diseases. It highlights a newly established protocol converting primary human hepatocytes from healthy donor livers into bipotent progenitor cells (hCdHs), and their extension into generating liver organoids for diverse biomedical applications.
- Biomaterials
- 2023.10.30
- 전용웅(Stanford University, 현 KAIST)
Possible Genetic Risks from Heat-Damaged DNA in Food
- ACS Central Sci. Publication Date:June 1, 20 | https://doi.org/10.1021/acscentsci.2c01247
- 2023.06
- 생명과학
Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage
- Part. Fibre Toxicol. 2023 Jan 10;20(1):2 | https://doi.org/10.1186/s12989-022-00512-8
- 2023.01
- 의약학
Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage
- Part. Fibre Toxicol. 2023 Jan 10;20(1):2 | https://doi.org/10.1186/s12989-022-00512-8
- 2023.01
- 의약학