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통합검색

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'targeted therapy' 에 대한 통합검색결과 524건입니다.

한빛사524건

최신순
관련도순

- Arnold Park(Vir Biotechnology Inc.)
- 황승민(Vir Biotechnology Inc. (현 Broad Institute of MIT and Harvard))
  Interview
Shared host genetic landscape of respiratory viral infection
- Proc. Natl. Acad. Sci. USA May 20 2025, 122 (20) | https://doi.org/10.1073/pnas.2414202122
- 2025.05
- 생명과학
Tumor-Targeted Exosome-Based Heavy Atom-Free Nanosensitizers With Long-Lived Excited States for Safe and Effective Sono-Photodynamic Therapy of Solid
- Adv. Healthc. Mater. Apr 01 2025, | https://doi.org/10.1002/adhm.202500927
- 2025.04
- 바이오·의료융합
Advancing pancreatic cancer therapy by mesothelin-specific nanobody conjugation
- Mol. Cancer Apr 24 2025, 24 (1) 124 | https://doi.org/10.1186/s12943-025-02325-7
- 2025.04
Cell membrane nanoparticles in cancer therapy: From basic structure to surface functionalization
- J. Control. Release Apr 18 2025, S0168-3659(25)00372-4 | https://doi.org/10.1016/j.jconrel.2025.113752
- 2025.04
- 바이오·의료융합
Regulated cell death mechanisms in mitochondria-targeted phototherapy
- J. Control. Release Apr 12 2025, S0168-3659(25)00340-2 | https://doi.org/10.1016/j.jconrel.2025.113720
- 2025.04
Engineering IgG antibodies for intracellular targeting and drug delivery
- J. Control. Release Apr 11 2025, S0168-3659(25)00347-5 | https://doi.org/10.1016/j.jconrel.2025.113727
- 2025.04
- 생명과학
- 조원화(University of Illinois Chicago)
Cholesterol-targeting Wnt?β-catenin signaling inhibitors for colorectal cancer
- Nat. Chem. Biol. 16 April 2025 | https://doi.org/10.1038/s41589-025-01870-y
- 2025.04
- 생명과학
Thermoresistant flagellin-adjuvanted cancer vaccine combined with photothermal therapy synergizes with anti-PD-1 treatment
- J. Immunother. Cancer Mar 21 2025, 13 (3) e010272 | https://doi.org/10.1136/jitc-2024-010272
- 2025.03
- 의약학
- 현혜선(University of North Carolina at Chapel Hill)
Tumor-specific surface marker-independent targeting of tumors through nanotechnology and bioorthogonal glycochemistry
- J. Clin. Invest. Mar 11 2025, e184964 | https://doi.org/10.1172/JCI184964
- 2025.03
- 바이오·의료융합
Generation of hypoimmunogenic universal iPS cells through HLA-type gene knockout
- Exp. Mol. Med. Mar 14 2025, | https://doi.org/10.1038/s12276-025-01422-3
- 2025.03
- 생명과학
Cytoplasmic WEE1 promotes resistance to PD-1 blockade through hyperactivation of the HSP90A/TCL1/AKT signaling axis in NANOGhigh tumors
- Cancer Immunol. Res. Mar 11 2025, | https://doi.org/10.1158/2326-6066.CIR-24-0379
- 2025.03
- 의약학
Novel anti-CD73-IL-2v bispecific fusion protein augments antitumor immunity by alleviating immunosuppressive adenosine pathways in CD8+ T cells
- J. Immunother. Cancer Mar 13 2025, 13 (3) e008594 | https://doi.org/10.1136/jitc-2023-008594
- 2025.03
- 의약학
Time-Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects
- Adv. Funct. Mater. 12 March 2025 | https://doi.org/10.1002/adfm.202418560
- 2025.03
- 의약학
Unlocking Multimodal Nonlinear Microscopy for Deep-Tissue Imaging under Continuous-Wave Excitation with Tunable Upconverting Nanoparticles
- Adv. Mater. Mar 21 2025, | https://doi.org/10.1002/adma.202502739
- 2025.03
- 바이오·의료융합
Inflamed Tissue-Targeting Polyphenol-Condensed Antioxidant Nanoparticles with Therapeutic Potential
- Adv. Healthc. Mater. Mar 04 2025, | https://doi.org/10.1002/adhm.202500495
- 2025.03
- 바이오·의료융합
이서희

POSTECH

표적 단백질 분해(Targeted Protein Degradation, TPD)는 기존의 소분자 억제제(small molecule inhibitors)와는 달리 질병을 유발하는 단백질 자체를 분해하여 치료 효과를 극대화하는 혁신적인 치료 전략입니다. 기존 소분자 치료제는 단백질 활성을 일시적으로 억제하는 방식이기 때문에 내성(resistance)이나 재발(recurrence) 문제가 발생할 가능성이 큽니다. 하지만 TPD 기술은 목표 단백질을 선택적으로 제거하여 장기적인 치료 효과를 제공할 수 있다는 장점이 있습니다.
- ACS Nano
- 2025.03.17
Apolipoprotein Fusion Enables Spontaneous Functionalization of mRNA Lipid Nanoparticles with Antibody for Targeted Cancer Therapy
- ACS Nano Feb 05 2025, | https://doi.org/10.1021/acsnano.4c16562
- 2025.02
- 생명과학
- 이서희(POSTECH)
  Interview
- 김원종(POSTECH)
Targeted Protein Degradation in Cancer Therapy via Hydrophobic Polymer-Tagged Nanoparticles
- ACS Nano Feb 21 2025, | https://doi.org/10.1021/acsnano.4c12747
- 2025.02
- 바이오·의료융합
Glycoengineered stem cell-derived extracellular vesicles for targeted therapy of acute kidney injury
- Biomaterials Feb 04 2025, 318 S0142-9612(25)00084-5 | https://doi.org/10.1016/j.biomaterials.2025.123165
- 2025.02
- 이주호(부산대학교)
- 유진욱(부산대학교 약학대학)
On-site sol-gel-sol transition of alginate enables reversible shielding/deshielding of tumor cell-activated nanoconjugates for precise local colorecta
- Chem. Eng. J. Volume 505, 1 February 2025, 158935 | https://doi.org/10.1016/j.cej.2024.158935
- 2025.02
- 의약학