한빛사179건

• • 안성진(The University of Tokyo)

  Synthesis of 2‘-formamidonucleoside phosphoramidites for suppressing the seed-based off-target effects of siRNAs

  • Nucleic Acids Res. Sep 05 2024, gkae741 | https://doi.org/10.1093/nar/gkae741

  • 2024.09

• • 최희진(National Institutes of Health (NIH))

  RNA helicase D1PAS1 resolves R-loops and forms a complex for mouse pachytene piRNA biogenesis required for male fertility

  • Nucleic Acids Res. Aug 20 2024, gkae712 | https://doi.org/10.1093/nar/gkae712

  • 2024.08

• • Yan Liu(성균관대학교)

  • 조재열(성균관대학교)

  Oral Piwi-Interacting RNA Delivery Mediated by Green Tea-Derived Exosome-Like Nanovesicles for the Treatment of Aortic Dissection

  • Adv. Healthc. Mater. Aug 01 2024, | https://doi.org/10.1002/adhm.202401466

  • 2024.08
  • 생명과학

• • 유미경(Alnylam Pharmaceuticals)

  Evaluating the oral delivery of GalNAc-conjugated siRNAs in rodents and non-human primates

  • Nucleic Acids Res. May 14 2024, gkae350 | https://doi.org/10.1093/nar/gkae350

  • 2024.05
  • 의약학

• • 백승찬(서울대학교, IBS RNA연구단, 현 브로드 연구소)

    Interview

  • 김보선(서울대학교, IBS RNA연구단)

  • 장하림(서울대학교, 기초과학연구원)

  • 김빛내리(서울대학교, IBS RNA연구단)

  Structural atlas of human primary microRNAs generated by SHAPE-MaP

  • Mol. Cell March 05, 2024 | https://doi.org/10.1016/j.molcel.2024.02.005

  • 2024.03
  • 생명과학
• 

  고숭천

  성균관대학교

  제가 초점을 둔 분야는 유용한 생산물을 생산하기 위해 미생물 유전자 조작할 수 있는 tool을 발견, 활용하는 합성생물학, 대사공학에 기반을 두고 있습니다. 그 중에서도 본 논문은 생명과학, 생명공학에 폭넓게 사용되는 CRISPR 기술 중 RNA를 타겟으로 하는 dead Cas13a를 박테리아에 적용하고자 하였으며, 특히 박테리아 내의 small RNA와 messenger RNA를 타겟할 수 있도록 시스템을 최적화했습니다.

  • Nucleic Acids Res.
  • 2023.12.05

• • 고숭천(성균관대학교)

    Interview

  • 우한민(성균관대학교)

  CRISPR-dCas13a system for programmable small RNAs and polycistronic mRNA repression in bacteria

  • Nucleic Acids Res. Nov 28 2023, gkad1130 | https://doi.org/10.1093/nar/gkad1130

  • 2023.11
  • 생명과학

• • 조정남(Durham University)

  The CARBON CATABOLITE REPRESSION 4A-mediated RNA deadenylation pathway acts on the transposon RNAs that are not regulated by small RNAs

  • New Phytol. Nov 27 2023, | https://doi.org/10.1111/nph.19435

  • 2023.11
  • 생명과학

• • 야다발리하리 찬다나(연세대학교)

  • 박수연(연세대학교)

  • 양성욱(연세대학교)

  Tailed-Hoogsteen Triplex DNA Silver Nanoclusters Emit Red Fluorescence upon Target miRNA Sensing

  • Small Nov 15 2023, | https://doi.org/10.1002/smll.202306793

  • 2023.11
  • 바이오·의료융합

• • 강하라(인천대학교)

  • 예정용(인천대학교)

  Small interfering RNA (siRNA)-based therapeutic applications against viruses: principles, potential, and challenges

  • J. Biomed. Sci. Oct 16 2023, 30 (1) | https://doi.org/10.1186/s12929-023-00981-9

  • 2023.10
  • 생명과학

• • 진병준(경상국립대학교)

    Interview

  • 전현진(경상국립대학교)

  • 김민철(경상국립대학교)

  Host-induced gene silencing is a promising biological tool to characterize the pathogenicity of Magnaporthe oryzae and control fungal disease in rice.

  • Plant Cell Environ. Sep 12 2023 | https://doi.org/10.1111/pce.14721

  • 2023.09
  • 생명과학

• • 이새별(중앙대학교)

  • 김학균(중앙대학교)

  Emerging roles of tRNA-derived small RNAs in cancer biology

  • Exp. Mol. Med. 2023 Jul 10 | https://doi.org/10.1038/s12276-023-01038-5

  • 2023.07
  • 생명과학

• • 장인철(Temasek Life Sciences Laboratory, National University of Singapore)

  HISTONE DEACETYLASE 9 promotes hypocotyl-specific auxin response under shade

  • Plant J. 31 July 2023 | https://doi.org/10.1111/tpj.16410

  • 2023.07
  • 생명과학

• • 안인숙(한국과학기술원)

  • 한진주(의과학대학원, 한국과학기술원)

  Where should siRNAs go: applicable organs for siRNA drugs

  • Exp. Mol. Med. 2023 Jul 10 | https://doi.org/10.1038/s12276-023-00998-y

  • 2023.07
  • 생명과학

• • 장전옥(한양대학교)

  • 이민형(한양대학교)

  Delivery systems of therapeutic nucleic acids for the treatment of acute lung injury/acute respiratory distress syndrome

  • J. Control. Release 2023 Jun 19;360:1-14 | https://doi.org/10.1016/j.jconrel.2023.06.018

  • 2023.06
  • 바이오·의료융합

• • 이영윤(서울대학교)

  • 김해동(서울대학교, 현 University of Washington )

  • 김빛내리(서울대학교)

  Sequence determinant of small RNA production by DICER

  • Nature 2023 Mar;615(7951):323-3 | https://doi.org/10.1038/s41586-023-05722-4

  • 2023.03
  • 생명과학

• • 신민욱(University of Massachusetts Chan Medical School)

  Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection

  • Proc. Natl. Acad. Sci. USA 2023 Mar 14;120(11):e2219523120 | https://doi.org/10.1073/pnas.2219523120

  • 2023.03
  • 의약학

• • 이영윤(서울대학교, 기초과학연구원)

  • 이한솔(서울대학교)

  • 김해동(서울대학교, 기초과학연구원)

  • 김빛내리(서울대학교, 기초과학연구원)

  • 노성훈(서울대학교)

  Structure of the human DICER?pre-miRNA complex in a dicing state

  • Nature Published: 22 February 2023 | https://doi.org/10.1038/s41586-023-05723-3

  • 2023.02
  • 생명과학

• • 이승재(Memorial Sloan Kettering Cancer Center)

  Promiscuous splicing-derived hairpins are dominant substrates of tailing-mediated defense of miRNA biogenesis in mammals

  • Cell Reports 2023 Feb 16;42(2):112111 | https://doi.org/10.1016/j.celrep.2023.112111

  • 2023.02
  • 생명과학

• • 이아름(한국생명공학연구원)

  • 조혜선(한국생명공학연구원)

  The spliceophilin CYP18-2 is mainly involved in the splicing of retained introns under heat stress in Arabidopsis

  • J. Integr. Plant Biol. First published: 13 January 2023 | https://doi.org/10.1111/jipb.13450

  • 2023.01
  • 생명과학