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1single cell RNA-sequencing

'single cell RNA-sequencing' 에 대한 통합검색결과 68건입니다.

한빛사68건

최신순
관련도순

송유라

Universit? Libre de Bruxelles

그 동안 각기 다른 기관을 구성하는 상피세포에 스트레스를 주었을 때, 해당 기관을 구성하는 세포들이 어떤 식으로 반응하는 지에 대한 연구는 계속되어 왔습니다. 특히 oncogene을 활성화 시킬 때 혹은 특정 타입의 세포를 인위적으로 절제했을 때, 어떻게 세포가 재분화를 하는가에 대해서는 정말 다양한 결과물들이 나와있습니다. 하지만 물리적 스트레스를 가했을 때, 세포 단위에서 어떤 반응이 일어나는가에 대해서는 잘 알려져 있지 않았습니다.
- Nat. Commun.
- 2024.12.24
김봉준

University of Texas MD Anderson Cancer Center

폐는 공기중에 직접적으로 노출되어 있어, 다양한 박테리아, 바이러스, 또는 여러 환경 인자 (NO2, O3, 미세먼지, 담배연기 등)로 인해 미세한 손상을 입을 수 있습니다. 손상된 폐는 줄기/전구 (stem/progenitor) 세포들에 의해 재생 (regeneration) 되어 기능을 회복하지만, 전구 세포들이 제 기능을 하지 못하면 폐는 재생되지 않고 섬유화 (Fibrosis) 등의 질병이 발생할 수 있습니다.
- Nat. Commun.
- 2024.10.31
- 이찬주(국립암센터)
- 박은정(국립암센터국제암대학원대학교)
Galectin-9 Mediates the Functions of Microglia in the Hypoxic Brain Tumor Microenvironment
- Cancer Res. August 29 2024 | https://doi.org/10.1158/0008-5472.CAN-23-3878
- 2024.08
- 의약학
Regenerative Role of Lrig1+ Cells in Kidney Repair
- J. Am. Soc. Nephrol. Aug 09 2024, | https://doi.org/10.1681/ASN.0000000000000462
- 2024.08
- 의약학
CX3CR1+ macrophages interact with hepatic stellate cells to promote hepatocellular carcinoma through CD8+ T cell suppression
- Hepatology Jul 19 2024, | https://doi.org/10.1097/HEP.0000000000001021
- 2024.07
- 의약학
- Fahad Hassan Shah(조선대학교 약학대학)
- 이헌우(조선대학교 약학대학)
Endothelial and macrophage interactions in the angiogenic niche
- Cytokine Growth Factor Rev. Jul 14 2024, S1359-6101(24)00048-0 | https://doi.org/10.1016/j.cytogfr.2024.07.005
- 2024.07
- 생명과학
Single-cell transcriptome analysis reveals subtype-specific clonal evolution and microenvironmental changes in liver metastasis of pancreatic adenocar
- Mol. Cancer May 03 2024, 23 (1) 87 | https://doi.org/10.1186/s12943-024-02003-0
- 2024.05
- 생명과학
- 이민경(Geisel School of Medicine at Dartmouth)
Associations in cell type-specific hydroxymethylation and transcriptional alterations of pediatric central nervous system tumors
- Nat. Commun. 30 April 2024 | https://doi.org/10.1038/s41467-024-47943-9
- 2024.04
- 이수형(Vanderbilt University Medical Center)
Amphiregulin switches progenitor cell fate for lineage commitment during gastric mucosal regeneration
- Gastroenterology Mar 14 2024, S0016-5085(24)00290-7 | https://doi.org/10.1053/j.gastro.2024.03.009
- 2024.03
- 의약학
Targeted deletion of CD244 on monocytes promotes differentiation into anti-tumorigenic macrophages and potentiates PD-L1 blockade in melanoma
- Mol. Cancer Feb 29 2024, 23 (1) 45 | https://doi.org/10.1186/s12943-024-01936-w
- 2024.02
- 의약학
High-dimensional profiling of regulatory T cells in psoriasis reveals an impaired skin-trafficking property
- EBioMedicine Feb 01 2024, 100 S2352-3964(24)00020-3 | https://doi.org/10.1016/j.ebiom.2024.104985
- 2024.02
- 의약학
이효형

서울대학교, Icahn School of Medicine at Mount Sinai

Psoriasis is a chronic, T-cell-mediated inflammatory skin disease with a Th17-skewed immune phenotype. Regulatory T cells (Tregs) play a key role in suppressing the inflammatory immune response and inducing immune homeostasis and self-tolerance. While the role of Tregs in the pathogenesis of psoriasis has been proposed, the exact mechanisms of action and the molecular characterization of skin-homing psoriatic Tregs has not yet been well explored.
- EBioMedicine
- 2024.02.16
Gut ribotoxic stress responses facilitate dyslipidemia via metabolic reprogramming: an environmental health prediction
- Theranostics Published 2024-1-20, 14 (3) | https://doi.org/10.7150/thno.88586
- 2024.01
- 의약학
Single-cell transcriptome sequencing of plant leaf expressing anti-HER2 VHH-FcK cancer therapeutic protein
- Sci. Data Dec 19 2023, 10 (1) | https://doi.org/10.1038/s41597-023-02833-5
- 2023.12
- 백경인(Georgia Tech and Emory University)
  Interview
- 조한중(Georgia Tech and Emory University)
HEG1 Protects Against Atherosclerosis by Regulating Stable Flow-Induced KLF2/4 Expression in Endothelial Cells
- Circulation Dec 15 2023, | https://doi.org/10.1161/CIRCULATIONAHA.123.064735
- 2023.12
- 생명과학
Integrative single-cell transcriptome analysis provides new insights into post-COVID-19 pulmonary fibrosis and potential therapeutic targets
- J. Med. Virol. 2023 Nov;95(11):e29201 | https://doi.org/10.1002/jmv.29201
- 2023.11
- 의약학
- Brian S. Kim(Icahn School of Medicine at Mount Sinai)
IL-33 Potentiates Histaminergic Itch
- J. Allergy Clin. Immunol. Nov 18 2023, S0091-6749(23)01465-3 | https://doi.org/10.1016/j.jaci.2023.08.038
- 2023.11
Microenvironmental network of clonal CXCL13+CD4+ T cells and regulatory T cells in pemphigus chronic blisters.
- J. Clin. Invest. Oct 10 2023, e166357 | https://doi.org/10.1172/JCI166357
- 2023.10
- 의약학
Cyclic Stretch Promotes Cellular Reprogramming Process through Cytoskeletal-Nuclear Mechano-Coupling and Epigenetic Modification.
- Adv. Sci. Sep 19 2023 | https://doi.org/10.1002/advs.202303395
- 2023.09
- 의약학
- 박요셉(Harvard Medical School)
- 김두연(Harvard Medical School/ Massachusetts General Hospital)
Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model
- Nat. Neurosci. 2023 Aug 24 | https://doi.org/10.1038/s41593-023-01415-3
- 2023.08
- 의약학