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1neurodegeneration

'neurodegeneration' 에 대한 통합검색결과 348건입니다.

한빛사348건

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EBP1 potentiates amyloid β pathology by regulating γ-secretase
- Nature Aging 08 January 2025 | https://doi.org/10.1038/s43587-024-00790-1
- 2025.01
- 의약학
- 함아롬(Columbia University Irving Medical Center)
Synaptic and cognitive impairment associated with L444P heterozygous glucocerebrosidase mutation
- Brain Nov 20 2024, awae380 | https://doi.org/10.1093/brain/awae380
- 2024.11
- 의약학
- 박혜진(KAIST)
- 감태인(KAIST / Johns Hopkins University)
α-Synuclein pathology as a target in neurodegenerative diseases
- Nat. Rev. Neurol. 28 November 2024 | https://doi.org/10.1038/s41582-024-01043-w
- 2024.11
- 의약학
- 김혜연(연세대학교 약학대학)
  Interview
- 김영수(연세대학교 약학과)
Chemical-Driven Amyloid Clearance for Therapeutics and Diagnostics of Alzheimer‘s Disease
- Acc. Chem. Res. Nov 04 2024, | https://doi.org/10.1021/acs.accounts.4c00458
- 2024.11
- 의약학
- 이수진(UMass Chan Medical School)
Emerging roles of antimicrobial peptides in innate immunity, neuronal function, and neurodegeneration
- Trends Neurosci. 2024 Oct 9:S0166-2236(24)00173-5 | https://doi.org/10.1016/j.tins.2024.09.001
- 2024.10
- 생명과학
- 노광식(Indiana University School of Medicine)
Pathway enrichment in genome-wide analysis of longitudinal Alzheimer‘s disease biomarker endophenotypes
- Alzheimers. Dement. Oct 23 2024, | https://doi.org/10.1002/alz.14308
- 2024.10
- 생명과학
- 박탐이나(Indiana University School of Medicine)
- 노광식(Indiana University School of Medicine)
Plasma miRNAs across the Alzheimer‘s disease continuum: Relationship to central biomarkers
- Alzheimers. Dement. Sep 18 2024, | https://doi.org/10.1002/alz.14230
- 2024.09
- 정선우(서울대학교 의과대학)
- 묵인희(서울대학교 의과대학)
Blockade of STING activation alleviates microglial dysfunction and a broad spectrum of Alzheimer’s disease pathologies
- Exp. Mol. Med. 02 September 2024 | https://doi.org/10.1038/s12276-024-01295-y
- 2024.09
- 신경철(Qatar Biomedical Research Institute, HBKU)
- 박용수(Qatar Biomedical Research Institute, HBKU)
Cholesterol imbalance and neurotransmission defects in neurodegeneration
- Exp. Mol. Med. 01 August 2024 | https://doi.org/10.1038/s12276-024-01273-4
- 2024.08
- 생명과학
- 이상환(서울대학교 의과대학)
- 이승재(서울대학교 의과대학)
Amyloid-β-activated microglia can induce compound proteinopathies
- Brain Aug 28 2024, awae221 | https://doi.org/10.1093/brain/awae221
- 2024.08
- 의약학
Overview Of a Novel Osmotin Abolishes Abnormal Metabolic-Associated Adiponectin Mechanism in Alzheimer‘s disease: Peripheral and CNS Insights
- Ageing Res. Rev. Aug 05 2024, S1568-1637(24)00265-4 | https://doi.org/10.1016/j.arr.2024.102447
- 2024.08
Central Role of Hypothalamic Circuits for Acupuncture‘s Anti-Parkinsonian Effects
- Adv. Sci. Aug 09 2024, | https://doi.org/10.1002/advs.202403245
- 2024.08
- 의약학
- Andrew S. Yoo(Washington University School of Medicine)
Modeling late-onset Alzheimer’s disease neuropathology via direct neuronal reprogramming
- Science 2024 Aug 2;385(6708):adl2992 | https://doi.org/10.1126/science.adl2992
- 2024.08
Assessing cognitive impairment and disability in older adults through the lens of whole brain white matter patterns
- Alzheimers. Dement. Jul 12 2024, | https://doi.org/10.1002/alz.14094
- 2024.07
- 바이오·의료융합
- 이홍균(Harvard Medical School, Brigham and Women's Hospital)
[SPOTLIGHT] STING: Stay near to STIM(1) neuroprotection
- Mol. Cell VOLUME 84, ISSUE 14, P2596-2597, JULY 25, 2024 | https://doi.org/10.1016/j.molcel.2024.06.034
- 2024.07
- 의약학
Gba1 E326K renders motor and non-motor symptoms with pathologic α-syn, tau and glial activation
- Brain Jul 08 2024, awae222 | https://doi.org/10.1093/brain/awae222
- 2024.07
- 생명과학
- 김정수(Indiana University)
Loss of Inpp5d has disease-relevant and sex-specific effects on glial transcriptomes
- Alzheimers. Dement. Jun 26 2024, | https://doi.org/10.1002/alz.13901
- 2024.06
- 생명과학
- 김진희(세종대학교)
Hypertension in an Ageing Population: Diagnosis, Mechanisms, Collateral Health Risks, Treatments, and Clinical Challenges
- Ageing Res. Rev. May 18 2024, S1568-1637(24)00162-4 | https://doi.org/10.1016/j.arr.2024.102344
- 2024.05
- 김동훈(Johns Hopkins University School of Medicine, 현 동아대학교 의과대학)
- 고한석(Johns Hopkins University School of Medicine)
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
- Nat. Commun. May 31 2024, 15 (1) 4663 | https://doi.org/10.1038/s41467-024-49016-3
- 2024.05
- 생명과학
남예림

한양대학교

Astrocyte는 뇌에서 가장 풍부한 glial cell이며, 이들의 주요 역할은 ROS를 청소하고 과도한 excitotoxic glutamate, 유해한 lipids 및 pathological protein aggregates를 제거하는 등 다양한 메커니즘을 통해 세포외 및 세포내 독성으로부터 neuronal cell을 보호하는 것입니다. 또한 neurotrophic factors와 pro-inflammatory cytokine을 방출하고, 건강한 미토콘드리아를 Astrocyte에서 손상된 neuronal cell로 전달합니다.
- J. Adv. Res.
- 2024.04.08