한빛사94건

• • 장민철(KAIST)

  • 박지호(KAIST)

  Inhalable mRNA Nanoparticle with Enhanced Nebulization Stability and Pulmonary Microenvironment Infiltration

  • ACS Nano Aug 22 2024, | https://doi.org/10.1021/acsnano.4c05653

  • 2024.08
  • 바이오·의료융합

• • 곽기정(University of Maryland)

  • 석정수(University of Maryland, Johns Hopkins University School of Medicine)

  Brain Nucleic Acid Delivery and Genome Editing via Focused Ultrasound-Mediated Blood-Brain Barrier Opening and Long-Circulating Nanoparticles

  • ACS Nano Aug 22 2024, | https://doi.org/10.1021/acsnano.4c05270

  • 2024.08
  • 바이오·의료융합

• • 신광수(Yale University, 인하대학교)

  Branching in poly(amine-co-ester) polyplexes impacts mRNA transfection

  • Biomaterials Jun 27 2024, 311 S0142-9612(24)00226-6 | https://doi.org/10.1016/j.biomaterials.2024.122692

  • 2024.06
  • 바이오·의료융합

• • 황현정(KAIST)

  • 김윤기(KAIST)

  Molecular mechanisms of circular RNA translation

  • Exp. Mol. Med. Jun 14 2024, | https://doi.org/10.1038/s12276-024-01220-3

  • 2024.06
  • 생명과학

• • 이혜민(University of Texas MD Anderson Cancer Center)

  VHL governs m6A modification and PIK3R3 mRNA stability in clear cell renal cell carcinomas

  • J. Clin. Invest. Apr 15 2024, 134 (8) e179560 | https://doi.org/10.1172/JCI179560

  • 2024.04

• • 김경희(Massachusetts General Hospital / Harvard Medical School)

  • 이종민(Massachusetts General Hospital / Harvard Medical School)

  Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington‘s disease

  • Proc. Natl. Acad. Sci. USA Apr 16 2024, 121 (16) | https://doi.org/10.1073/pnas.2322924121

  • 2024.04
  • 생명과학

• • 신하은(성균관대학교, 현 하와이주립대)

    Interview

  • 박우람(성균관대학교)

  Enhancing CAR-NK Cells Against Solid Tumors Through Chemical and Genetic Fortification with DOTAP-Functionalized Lipid Nanoparticles

  • Adv. Funct. Mater. 07 March 2024 | https://doi.org/10.1002/adfm.202315721

  • 2024.03
  • 바이오·의료융합

• • 정원선(충남대학교)

  • 정혜연(한국생명공학연구원)

  • 이은정(충남대학교)

  • 김윤경(한국생명공학연구원)

  • 최준식(충남대학교)

  Modulating Lipid Nanoparticles with Histidinamide-Conjugated Cholesterol for Improved Intracellular Delivery of mRNA

  • Adv. Healthc. Mater. Feb 12 2024, | https://doi.org/10.1002/adhm.202303857

  • 2024.02
  • 바이오·의료융합

• • 이영석(KAIST)

    Interview

  • 김빛내리(서울대학교)

  Deadenylation kinetics of mixed poly(A) tails at single-nucleotide resolution

  • Nat. Struct. Mol. Biol. Feb 19 2024, | https://doi.org/10.1038/s41594-023-01187-1

  • 2024.02
  • 생명과학

• • Jing Cai(전남대학교)

  • 강훈승(전남대학교, Jiangsu Normal University)

  FIONA1-mediated mRNA m6 A methylation regulates the response of Arabidopsis to salt stress

  • Plant Cell Environ. Jan 09 2024, | https://doi.org/10.1111/pce.14807

  • 2024.01
  • 생명과학

• • 고민수(덕성여자대학교, 연세대학교)

  • 임혜솔(덕성여자대학교)

  • Hao Jin(덕성여자대학교)

  • 문애리(덕성여자대학교)

  ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells

  • Autophagy Jan 30 2024, | https://doi.org/10.1080/15548627.2024.2305063

  • 2024.01
  • 의약학

• • 조정남(Durham University)

  The CARBON CATABOLITE REPRESSION 4A-mediated RNA deadenylation pathway acts on the transposon RNAs that are not regulated by small RNAs

  • New Phytol. Nov 27 2023, | https://doi.org/10.1111/nph.19435

  • 2023.11
  • 생명과학

• • 구세영(Harvard Medical School, 현 협성대학교)

  Nano-bio interactions in mRNA nanomedicine: Challenges and opportunities for targeted mRNA delivery

  • Adv. Drug Deliv. Rev. Oct 21 2023, S0169-409X(23)00431-3 | https://doi.org/10.1016/j.addr.2023.115116

  • 2023.10
  • 바이오·의료융합

• • 김도균(Cleveland Clinic)

    Interview

  • 정재웅(Cleveland Clinic)

  Viral codon optimization on SARS-CoV-2 Spike boosts immunity in the development of COVID-19 mRNA vaccines

  • J. Med. Virol. Volume95, Issue10 October 2023 e29183 | https://doi.org/10.1002/jmv.29183

  • 2023.10
  • 생명과학

• • 정유진(연세대학교)

  • 최준식(연세대학교)

  • 임용범(연세대학교)

  Cooperative Assembly of Self-Adjusting α-Helical Coiled Coils along the Length of an mRNA Chain to Form a Thermodynamically Stable Nanotube Carrier.

  • J. Am. Chem. Soc. Sep 21 2023 | https://doi.org/10.1021/jacs.3c05638

  • 2023.09
  • 바이오·의료융합
• 

  조성윤

  Cornell University

  mTOR (Mechanistic target of rapamycin)은 target 단백질의 인산화에 관여하는 kinase입니다. 세포에서 mTOR은 성장인자나 영양상태 등을 통합조절하는 역할을 하기 때문에 세포성장에서 매우 중요한 단백질입니다. 특히 암세포들의 활발한 증식은 mTOR의 높은 활성과 관련되어 있어 mTOR의 생합성 억제와 활성 저해는 항암 연구 분야에서 주목을 받아 왔습니다.

  • Mol. Cell
  • 2023.08.29

• • 이새별(중앙대학교)

  • 김학균(중앙대학교)

  Emerging roles of tRNA-derived small RNAs in cancer biology

  • Exp. Mol. Med. 2023 Jul 10 | https://doi.org/10.1038/s12276-023-01038-5

  • 2023.07
  • 생명과학

• • 서제니(서울대학교, 기초과학연구원)

  • 정수진(서울대학교, 기초과학연구원)

  • 김빛내리(서울대학교, 기초과학연구원)

  Functional viromic screens uncover regulatory RNA elements

  • Cell July 05, 2023 | https://doi.org/10.1016/j.cell.2023.06.007

  • 2023.07
  • 생명과학

• • 한건희(고려대학교, 한국과학기술연구원(KIST))

  • 윤홍열(한국과학기술연구원(KIST), 의약소재연구센터)

  • 이수현(Stanford University)

  Advances in mRNA therapeutics for cancer immunotherapy: From modification to delivery

  • Adv. Drug Deliv. Rev. Available online 25 June 2023 | https://doi.org/10.1016/j.addr.2023.114973

  • 2023.06
  • 바이오·의료융합

• • Umme Amara(전남대학교)

  • 강훈승(전남대학교)

  FLK is an mRNA m6A reader that regulates floral transition by modulating the stability and splicing of FLC in Arabidopsis

  • Mol. Plant. Volume 16, Issue 5, 1 May 2023 | https://doi.org/10.1016/j.molp.2023.04.005

  • 2023.05
  • 생명과학