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'korean pharmacy' 에 대한 통합검색결과 17건입니다.

한빛사17건

최신순
관련도순

Hy Dinh Nguyen

아주대학교

Quetiapine (QTP) is a first-line antipsychotic drug for the treatment of schizophrenia; however, lifelong daily administration of QTP tablets is associated with a low patient acceptance profile. Accordingly, substituting oral dosage forms with long-acting injectables can potentially improve patient compliance and treatment effectiveness.
- Adv. Sci.
- 2024.09.11
- 이나미(아주대학교 의과대학)
- 한승진(아주대학교 의과대학)
Characteristics and Clinical Course of Diabetes of the Exocrine Pancreas: A Nationwide Population-Based Cohort Study
- Diabetes Care Volume 45, Issue 5 May 2022 | https://doi.org/10.2337/dc21-1659
- 2022.05
- 의약학
Attenuation of the virulence of a recombinant influenza virus expressing the naturally truncated NS gene from an H3N8 equine influenza virus in mice
- Vet. Res. Published: 15 November 2016, 47:115 | DOI: 10.1186/s13567-016-0400-7
- 2016.11
- 생명과학
Detection of Severe Acute Respiratory Syndrome-Like, Middle East Respiratory Syndrome-Like Bat Coronaviruses and Group H Rotavirus in Faeces of Korean
- Transbound. Emerg. Dis. Version of Record online: 23 MAY 2016 | DOI: 10.1111/tbed.12515
- 2016.05
- 생명과학
Structural and biochemical insights into the role of testis-expressed gene 14 (TEX14) in forming the stable intercellular bridges of germ cells
- Proc. Natl. Acad. Sci. USA Published online before print September 21, 2015 | doi: 10.1073/pnas.1418606112
- 2015.09
- 생명과학
- 한경선(동국대학교 한의과대학)
- 김호준(동국대학교 일산한방병원)
Contrasting effects of fresh and fermented kimchi consumption on gut microbiota composition and gene expression related to metabolic syndrome in obese
- Mol. Nutr. Food Res. Accepted manuscript online: 17 FEB 2015, DOI: 10.1002/mnfr.201400780
- 2015.02
Md Nurunnabi

한국교통대학교

1. 논문관련 분야의 소개, 동향, 전망을 설명, 연구과정에서 생긴 에피소드 In this article we have focused on synthesis of green color graphene quantum dot, their characterization, in vitro and in vivo toxicity, imaging properties in cancer cell and finally biodistribution profile. We have mainly emphasized on in vivo toxicology study. Therefore we have done serum biochemistry study and histology study if organs of treated mice. As we know before thinking to apply any material for biological application, we should know biocompatibility, bio- degrability, toxicology, pharmacokinetics profile of that material. Recently Graphene quantum dots or photoluminescent graphene nanoparticles are considering one of the emerging materials for optical imaging which is one of the most important research fields of biomedical and bioengineering science. However, as soon as we have succeeded synthesis of photoluminescent graphene nanoparticle, we have decided to study the biological interaction properties of those materials. After successfully synthesis of the materials, we have started to observe in vitro and in vivo toxicity study. Dr. Kwang Jae Cho at Catholic University of Korea, who is one of our collaborators, helped us a lot to do the in vivo toxicity study. Some of the experiments were done at Dr. Cho's lab at Catholic University. We believe that our study and reported results will help other researcher to be advanced as no major or severe symptoms of toxicity were observed even for 3 weeks of observation. However, further modification or conjugation with other ligands or polymer would give it more optimized shape to make it more feasible and compatible for biological application. 2. 연구를 진행했던 소속기관 또는 연구소에 대해 소개 부탁 드립니다. Prof. Yong-kyu Lee is the principle investigator and mentor of our lab, named as Nano BioMedicine Lab ( https://sites.google.com/site/yongkyuleelab/ ), located at department of Chemical and Biological Engineering building of Korea N
- ACS Nano
- 2013.07.19
김미진

University of California, San Francisco

1. Can you please briefly summarize this paper? Can you please tell us the main difficulties you had in the laboratory work and how you overcame them? We know that varied drug response is in part due to interindividual genetic variation; however, most of the focus has been on the coding regions of drug-associated genes, such as cytochrome P450 enzymes, receptors and transporters. We investigated whether there is nucleotide variation in enhancers that could regulate drug transporters. We used a comparative genomics approach to test putative enhancers and validated their activity using the hydrodynamic tail vein technique in mice. The advantage of this approach was being able to test enhancer activity in vivo. We identified nucleotide variants in enhancers in an ethnically-diverse cohort and tested them for differential enhancer activity. In the end, we found a set of variants in one enhancer that was associated with methotrexate clearance, an anticancer drug. One of the main difficulties, however, was interpreting the association study data. One limitation of the methotrexate pharmacokinetic data we were analyzing was that the individuals in the study were children undergoing treatment. Usually, in a pharmacokinetic association study, individuals are healthy adults. 2. Please introduce your laboratory, university or organization to bio-researchers in Korea. University of California, San Francisco (UCSF) is a biomedical institution that houses some of the best medical, pharmacy, dental, nursing and graduate programs in the country. It is the only University of California school exclusively dedicated to graduate-level education and research in the biomedical and life sciences. It is located in San Francisco and has several large campuses throughout the city that provides health care in addition to research. One of the many strengths of this research community is the dynamic but also very collaborative environment. There are so many accomplished and we
- Clin. Pharmacol. Ther.
- 2011.07.29
Simple Determination of Double-Bond Positions in Long-Chain Olefins by Cross-Metathesis
- Angew. Chem.-Int. Edit. Article first published online: 24 JUN 2011 | DOI: 10.1002/anie.201102634
- 2011.06
- 의약학
- 배정우(성균관대학교)
- 이석용(성균관대학교)
Effects of CYP2C9*1/*13 on the pharmacokinetics and pharmacodynamics of meloxicam
- Br. J. Clin. Pharmacol. Volume 71, Issue 4, pages 550-555, April 2011| DOI: 10.1111/j.1365-2125.2010.03853.x
- 2011.04
- 의약학
- 강택진(동국대학교)
- Hiroaki Suga(서울대학교, University of Tokyo)
Synthesis of the Backbone Cyclic Peptide Sunflower Trypsin Inhibitor-1 Promoted by the Induced Peptidyl-tRNA Drop-off†
- Angew. Chem.-Int. Edit. Article first published online: 24 JAN 2011 | DOI: 10.1002/anie.201006963
- 2011.01
E-cadherin antagonizes transforming growth factor β1 gene induction in hepatic stellate cells by inhibiting RhoA–dependent Smad3 phosphorylatio
- Hepatology Volume 52, Issue 6, pages 2053–2064, December 2010. Article first published online: 1 OCT 2010 | DOI: 10.1002/hep.23931
- 2010.10
- 의약학
김창환

Pathobiology and Purdue Cancer Center, Purdue University

1. Can you please briefly summarize this paper and your work? T cells are the master regulators of the immune responses against pathogens. There are many T cell subsets performing different functions in our body. In the paper, we determined the global gene expression programs of these T cell subsets using cDNA microarrays containing 38,000 genes. We discovered that a T cell subset specialized in promoting B cell antibody production (called germinal center T cells) have a highly unique gene expression program among the T cell subsets. The detailed information obtained from this study on the genetic make-up of these T cells would help us understand in the future how the immune system produces antibodies to fight against pathogens. - Can you please tell us the main difficulties you had in the laboratory work and how you overcame them? The most difficult task was to isolate various T cell subsets of high purity and quality. Sometimes, we sorted for ~10 hours to get many millions of T cells required for the microarray study. Another difficult task was to select functionally important genes among several thousands of candidate genes. 2. Please introduce your laboratory, university or organization to bio researchers in Korea. The Purdue University is a strong university in terms of research and organization. It is particularly strong in the areas of basic science, engineering, pharmacy, computer science and management. I am affiliated with the Pathobiology department, Purdue Cancer Center and Purdue University Life Science Program (called PULSe). 3. Please tell us your experiences and your thoughts related to research activities abroad. It has been almost 10 years since I started my research in the USA. I realized that opportunities are abound for bright and productive people. It is not important where you come from. The important things are what you have done so far and what you will do in the future. 4. Can you provide some advice fo
- Blood
- 2004.09.22
Glutathione S-Transferase Mu Modulates the Stress-activated Signals by Suppressing Apoptosis Signal-regulating Kinase 1*
- J. Biol. Chem. 276, 12749-12755. First Published on January 18, 2001. doi: 10.1074/jbc.M005561200
- 2001.01
- 생명과학
- 이유미(부산대학교)
- 김규원(부산대학교, 현 서울대학교)
Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: A possible signal for vessel development
- Dev. Dyn. Volume 220 Issue 2, Pages 175 - 186 | Published Online: 18 Jan 2001
- 2001.01
- 김왕유(서울대학교)
- 박정일(서울대학교)
Steaming of Ginseng at High Temperature Enhances Biological Activity
- J. Nat. Prod 2000, 63 (12), pp 1702–1704 | DOI: 10.1021/np990152b
- 2000.10
- 이수경(전남대학교, 현 Oregon Health &Science University)
A Nuclear Factor, ASC-2, as a Cancer-amplified Transcriptional Coactivator Essential for Ligand-dependent Transactivation by Nuclear Receptors in Vivo
- J. Cell Biol. November 26, 1999 274, 34283-34293. | doi: 10.1074/jbc.274.48.34283
- 1999.11
- 생명과학

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