한빛사151건

• • 이광운(Harvard Medical School)

  Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1

  • Nat. Chem. Biol. Jul 04 2024, | https://doi.org/10.1038/s41589-024-01671-9

  • 2024.07
  • 생명과학

• • 우현주(이화여자대학교)

  • 오준수(강원대학교)

  • 이정신(강원대학교)

  • 김태수(이화여자대학교)

  N-terminal acetylation of Set1-COMPASS fine-tunes H3K4 methylation patterns

  • Sci. Adv. Jul 12 2024, 10 (28) eadl6280 | https://doi.org/10.1126/sciadv.adl6280

  • 2024.07
  • 생명과학

• • 한만혁(KAIST)

  • 박지현(KAIST)

  • 박민희(KAIST)

  Advances in the multimodal analysis of the 3D chromatin structure and gene regulation

  • Exp. Mol. Med. Apr 25 2024, | https://doi.org/10.1038/s12276-024-01246-7

  • 2024.04

• • 이민경(Geisel School of Medicine at Dartmouth)

  Associations in cell type-specific hydroxymethylation and transcriptional alterations of pediatric central nervous system tumors

  • Nat. Commun. 30 April 2024 | https://doi.org/10.1038/s41467-024-47943-9

  • 2024.04

• • 박세라(가천대학교)

  • 민은경(가천대학교)

  • 김수림(가천대학교)

  • 오병철(가천대학교 이길여암당뇨연구원)

  • 홍인선(가천대학교)

  Exploring Memory Function Beyond Immune Cells: ANGPTL4-Mediated Memory Functions in Tissue Resident Stem Cells

  • Adv. Sci. Apr 26 2024, | https://doi.org/10.1002/advs.202307545

  • 2024.04
  • 의약학

• • 성시범(The University of Texas at Austin)

  Chromatin sensing: Integration of environmental signals to reprogram plant development through chromatin regulators

  • J. Exp. Bot. Mar 04 2024, erae086 | https://doi.org/10.1093/jxb/erae086

  • 2024.03
  • 생명과학

• • 홍철종(서울대학교)

  • 서필준(서울대학교)

  Histone modification-dependent production of peptide hormones facilitates acquisition of pluripotency during leaf-to-callus transition in Arabidopsis

  • New Phytol. Feb 26 2024, | https://doi.org/10.1111/nph.19637

  • 2024.02
  • 생명과학

• • 김태헌(The Hospital for Sick Children,University of Toronto, 현 Case Western Reserve University)

  Poly(ADP-ribosyl)ation enhances nucleosome dynamics and organizes DNA damage repair components within biomolecular condensates

  • Mol. Cell January 11, 2024 | https://doi.org/10.1016/j.molcel.2023.12.019

  • 2024.01
  • 생명과학

• • Nur Aziz(성균관대학교)

  • 홍요한(성균관대학교)

  • 김한경(성균관대학교)

  • 김지혜(성균관대학교)

  • 조재열(성균관대학교)

  Tumor-suppressive functions of protein lysine methyltransferases

  • Exp. Mol. Med. Dec 01 2023, | https://doi.org/10.1038/s12276-023-01117-7

  • 2023.12
  • 생명과학

• • 송병준(National Institute on Alcohol Abuse and Alcoholism/NIH)

  Post-translational modifications of histone and non-histone proteins in epigenetic regulation and translational applications in alcohol-associated liv

  • Pharmacol. Ther. Oct 12 2023, S0163-7258(23)00211-5 | https://doi.org/10.1016/j.pharmthera.2023.108547

  • 2023.10

• • Ming Li Jin(가천대학교 약학대학)

  • 정광원(가천대학교)

  Histone modifications in drug-resistant cancers: From a cancer stem cell and immune evasion perspective

  • Exp. Mol. Med. Published: 03 July 2023 | https://doi.org/10.1038/s12276-023-01014-z

  • 2023.07
  • 생명과학
• 

  김태헌

  University of Toronto, 현 Case Western Reserve University

  Chromatin의 histone acetylation은 유전 정보의 transcription을 조절하는 중요한 역할을 합니다. Molecular dynamics 시뮬레이션과 일부 실험을 통해 acetylation이 histone tail의 dynamics을 증가시킨다는 것이 입증되었습니다. 하지만, 이 epigenetic modification이 하나의 histone에 초점을 맞춰 nucleosome의 structural dynamics에 어떻게 영향을 미치는지,

  • Proc. Natl. Acad. Sci. USA
  • 2023.07.18

• • 김태헌(University of Toronto, 현 Case Western Reserve University )

    Interview

  Correlating histone acetylation with nucleosome core particle dynamics and function

  • Proc. Natl. Acad. Sci. USA 2023 Apr 11;120(15):e2301063120 | https://doi.org/10.1073/pnas.2301063120

  • 2023.04
  • 생명과학

• • 유영석(서울대학교)

  • 김현경(고려대학교 의과대학)

  • 김근일(숙명여자대학교)

  • 백성희(서울대학교)

  Epigenetic regulation of autophagy by histone-modifying enzymes under nutrient stress

  • Cell Death Differ. 2023 Mar 30 | https://doi.org/10.1038/s41418-023-01154-9

  • 2023.03
  • 생명과학

• • 양보배(연세대학교 의과대학)

  • 김형표(연세대학교 의과대학)

  CTCF controls three-dimensional enhancer network underlying the inflammatory response of bone marrow-derived dendritic cells

  • Nat. Commun. 2023 Mar 8;14(1):1277 | https://doi.org/10.1038/s41467-023-36948-5

  • 2023.03
  • 생명과학

• • Natasha Christabella Sutopo(성균관대학교)

  • 김지혜(성균관대학교)

  • 조재열(성균관대학교)

  Role of histone methylation in skin cancers: Histone methylation-modifying enzymes as a new class of targets for skin cancer treatment

  • Biochim. Biophys. Acta-Rev. Cancer 2023 Feb 24;1878(3):188865 | https://doi.org/10.1016/j.bbcan.2023.188865

  • 2023.02
  • 생명과학

• • 이창후(UNIST)

  • 박지영(UNIST)

  Epigenetic regulation of Neuregulin 1 promotes breast cancer progression associated to hyperglycemia

  • Nat. Commun. 2023 Jan 27;14(1):439 | https://doi.org/10.1038/s41467-023-36179-8

  • 2023.01
  • 생명과학

• • 이도훈(서울대학교)

    Interview

  • 김선(서울대학교)

  Learning the histone codes with large genomic windows and three-dimensional chromatin interactions using transformer

  • Nat. Commun. 2022 Nov 5;13(1):6678 | https://doi.org/10.1038/s41467-022-34152-5

  • 2022.11
  • 의약학

• • 박지수(충북대학교)

  • 김경환(충북대학교)

  • 이선주(충북대학교)

  The role of histone modifications: from neurodevelopment to neurodiseases

  • Signal Transduct. Target. Ther. Published 06 July 2022 | https://doi.org/10.1038/s41392-022-01078-9

  • 2022.07
  • 생명과학

• • 김준일(충북대학교)

  • 이선주(충북대학교)

  • 김경환(충북대학교)

  Gene regulation by histone-modifying enzymes under hypoxic conditions: a focus on histone methylation and acetylation

  • Exp. Mol. Med. Published 22 July 2022 | https://doi.org/10.1038/s12276-022-00812-1

  • 2022.07
  • 생명과학