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'hepatocytes' 에 대한 통합검색결과 314건입니다.

한빛사314건

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Enhanced stem cell-mediated therapeutic immune modulation with zinc oxide nanoparticles in liver regenerative therapy
- Biomaterials Available online 4 March 2025, 123232 | https://doi.org/10.1016/j.biomaterials.2025.123232
- 2025.03
- 바이오·의료융합
A1AT dysregulation of metabolically stressed hepatocytes by Kupffer cells drives MASH and fibrosis
- Exp. Mol. Med. 12 February 2025 | https://doi.org/10.1038/s12276-025-01408-1
- 2025.02
Dual-mode action of scalable, high-quality engineered stem cell-derived SIRPα-extracellular vesicles for treating acute liver failure
- Nat. Commun. Published: 23 February 2025 | https://doi.org/10.1038/s41467-025-57133-w
- 2025.02
- 바이오·의료융합
- 김재준(University of California, San Francisco)
  Interview
AAV capsid prioritization in normal and steatotic human livers maintained by machine perfusion
- Nat. Biotechnol. 29 January 2025 | https://doi.org/10.1038/s41587-024-02523-6
- 2025.01
- 김재연(차의과학대학교, 현 Cedars-Sinai Medical Center)
- 김기진(차의과학대학교)
Modulation of PRL-1 within placental MSCs instigates the transition between EMT and MET subsequent to hepatic fibrosis
- Clin. Mol. Hepatol. Jan 22 2025, | https://doi.org/10.3350/cmh.2024.0741
- 2025.01
- 생명과학
Isoxazole-based molecules restore NK cell immune surveillance in hepatocarcinogenesis by targeting TM4SF5 and SLAMF7 linkage
- Signal Transduct. Target. Ther. Jan 20 2025, 10 (1) | https://doi.org/10.1038/s41392-024-02106-6
- 2025.01
- 의약학
Amphiphilic lipid conjugate-mediated surface engineering of placenta-derived mesenchymal stem cells for alleviating liver damage and fibrosis
- Chem. Eng. J. Volume 503, 1 January 2025, 158313 | https://doi.org/10.1016/j.cej.2024.15831
- 2025.01
- 생명과학
Drug repositioning of mesalamine via supramolecular nanoassembly for the treatment of drug-induced acute liver failure
- Theranostics 2025; 15(3):1122-1134 | https://www.thno.org/v15p1122
- 2025.01
- 바이오·의료융합
박정수

충북대학교 약학대학

저희 연구 주제는 비알코올성 지방간질환(Non-Alcoholic Fatty Liver Disease; NAFLD)입니다. 2023년, NAFLD는 대사 이상 지방간질환(Metabolic Dysfunction Associated Steatosis Liver Disease; MASLD)으로 명칭이 변경되며, 대사 장애와 연관된 개념 및 새로운 진단 기준이 추가되었습니다. 이러한 변화는 단순히 간에서의 지방 축적을 넘어 다양한 대사적, 염증성 경로가 복잡하게 얽혀 있음을 강조합니다.
- Metab.-Clin. Exp.
- 2025.01.02
- 이승재(Memorial Sloan Kettering Cancer Center)
Noncanonical role of ALAS1 as a heme-independent inhibitor of small RNA?mediated silencing
- Science 2024 Dec 20;386(6728):1427-1434 | https://doi.org/10.1126/science.adp9388
- 2024.12
- 생명과학
- 최유진(서울대학교, 대구가톨릭대학교)
- 이병훈(서울대학교)
Impaired chaperone-mediated autophagy leads to abnormal SORT1 (sortilin 1) turnover and CES1-dependent triglyceride hydrolysis
- Autophagy 29 Nov 2024 | https://doi.org/10.1080/15548627.2024.2435234
- 2024.11
- 의약학
HepScope: CNN-based single-cell discrimination of malignant hepatocytes
- J. Big Data 27 October 2024;11,149 | https://doi.org/10.1186/s40537-024-01024-2
- 2024.10
- 의약학
- Dashdulam Davaanyam(인하대학교 의과대학)
- 이자경(인하대학교 의과대학)
Hepatocyte activation and liver injury following cerebral ischemia promote HMGB1-mediated hepcidin upregulation in hepatocytes and regulation of syste
- Exp. Mol. Med. Oct 01 2024, | https://doi.org/10.1038/s12276-024-01314-y
- 2024.10
고윤진

아주대학교 의과대학

Our study centers on hepatocellular carcinoma, which is the most prevalent form of liver cancer, ranking as the sixth most common and third most lethal cancer globally. Despite advancements in treatment modalities, the prognosis of HCC remains bleak due to its heterogeneity. Hence, we aimed to develop a novel gene set and AI tool to identify malignant hepatocytes in scRNA-seq data, thereby addressing the lack of existing biomarkers and computational tools and contributing to the discovery of therapeutic targets.
- J. Big Data
- 2024.10.30
- 전지혜(Duke University)
The senescence-associated secretome of hedgehog-deficient hepatocytes drives MASLD progression
- J. Clin. Invest. Aug 27 2024, e180310 | https://doi.org/10.1172/JCI180310
- 2024.08
- 생명과학
Engineered lipid nanoparticles enable therapeutic gene silencing of GTSE1 for the treatment of liver fibrosis
- J. Control. Release Aug 22 2024, 374 S0168-3659(24)00551-0 | https://doi.org/10.1016/j.jconrel.2024.08.012
- 2024.08
- 의약학
Dual-Action Protein-siRNA Conjugates for Targeted Disruption of CD47-Signal Regulatory Protein α Axis in Cancer Therapy
- ACS Nano Aug 08 2024, | https://doi.org/10.1021/acsnano.4c06471
- 2024.08
- 바이오·의료융합
Regulation of hepatic lipogenesis by asymmetric arginine methylation
- Metab.-Clin. Exp. Aug 2024, 157 S0026-0495(24)00165-3 | https://doi.org/10.1016/j.metabol.2024.155938
- 2024.08
- 생명과학
- 권윤(Heidelberg University)
Induction of steatosis in primary human hepatocytes recapitulates key pathophysiological aspects of metabolic dysfunction-associated steatotic liver d
- J. Hepatol. Jul 06 2024, S0168-8278(24)02347-X | https://doi.org/10.1016/j.jhep.2024.06.040
- 2024.07
- 생명과학
Galectin 3-binding protein (LGALS3BP) depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1 (TGF-β1) availability and inhi
- Cancer Commun. Jul 28 2024, | https://doi.org/10.1002/cac2.12600
- 2024.07
- 의약학