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'fibril' 에 대한 통합검색결과 64건입니다.

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Anti-TLR2 immunotherapy modulates neuron-to-oligodendrocyte propagation of α-synuclein in mouse and human models
- Nat. Commun. Jan 30 2026, | https://doi.org/10.1038/s41467-026-68870-x
- 2026.01
- 의약학
- 송태정(University of Cincinnati, 현 University of Arizona)
Fast Myosin Binding Protein-C Is a Vital Regulator in Young and Aged Fast Skeletal Muscle Homeostasis
- J. Cachexia Sarcopenia Muscle Dec 2025, 16 (6) | https://doi.org/10.1002/jcsm.70106
- 2025.12
- 생명과학
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서울대학교

현대인은 알츠하이머병, 파킨슨병, 제2형 당뇨병, 백내장 등 다양한 질병에 노출되어 있습니다. 이 질병들은 공통적으로 단백질의 잘못된 접힘(misfolding) 또는 비정상적인 응집(aggregation)과 깊은 연관이 있는 것으로 알려져 있으며, 이러한 특성을 공유하는 질병은 현재까지 50가지가 넘는 것으로 보고되고 있습니다. 따라서 단백질 응집 현상의 기전을 밝히고 치료제의 타겟을 찾기 위한 시험관 연구가 활발히 이루어지고 있습니다.
- J. Am. Chem. Soc.
- 2025.12.31
Clearance of amyloid plaque via focused ultrasonication in a mouse model of Alzheimer’s disease
- Theranostics 2025.11.18;16(5):2310-2323. | doi:10.7150/thno.122123
- 2025.11
- 의약학
- 한무경(Max Planck Institute for Multidisciplinary Sciences)
Anle138b binds predominantly to the central cavity in lipidic Aβ₄? fibrils and modulates fibril formation
- Nat. Commun. Oct 03 2025, 16 (1) 8850 | https://doi.org/10.1038/s41467-025-64443-6
- 2025.10
- 생명과학
- 최호준(University of Washington)
Diffusing protein binders to intrinsically disordered proteins
- Nature Jul 30 2025, | https://doi.org/10.1038/s41586-025-09248-9
- 2025.07
- 한송이(University of California, Santa Barbara (현 Northwestern University))
Water-directed pinning is key to tau prion formation
- Proc. Natl. Acad. Sci. USA May 06 2025, 122 (18) | https://doi.org/10.1073/pnas.2421391122
- 2025.05
Biomimetic Dynamics of Nanoscale Groove and Ridge Topography for Stem Cell Regulation
- Adv. Mater. Apr 26 2025, | https://doi.org/10.1002/adma.202419416
- 2025.04
- 바이오·의료융합
- 허현(Rutgers University (현재, Hackensack Meridian Health CDI))
- 이상혁(Rutgers University, Piscataway)
Time-resolved tracking of cellulose biosynthesis and assembly during cell wall regeneration in live Arabidopsis protoplasts
- Sci. Adv. Mar 21 2025, 11 (12) eads6312 | https://doi.org/10.1126/sciadv.ads6312
- 2025.03
- 생명과학
Semantic variant primary progressive aphasia with ANXA11 p.D40G
- Alzheimers. Dement. Mar 2025, 21 (3) | https://doi.org/10.1002/alz.14566
- 2025.03
- 의약학
Graphene Quantum Dots Attenuate TDP-43 Proteinopathy in Amyotrophic Lateral Sclerosis
- ACS Nano Feb 03 2025, | https://doi.org/10.1021/acsnano.4c15283
- 2025.02
- 의약학
Second-generation anti-amyloid monoclonal antibodies for Alzheimer‘s disease: current landscape and future perspectives
- Transl. Neurodegener. Jan 27 2025, 14 (1) 6 | https://doi.org/10.1186/s40035-025-00465-w
- 2025.01
- 의약학
Bio-Orchestration of Cellular Organization and Human-Preferred Sensory Texture in Cultured Meat
- ACS Nano Jan 07 2025, | https://doi.org/10.1021/acsnano.4c15622
- 2025.01
- 바이오·의료융합
- Batakrishna Jana(UNIST)
- 유자형(UNIST)
Host-Guest Adduct as a Stimuli-Responsive Prodrug: Enzyme-Triggered Self-Assembly Process of a Short Peptide Within Mitochondria to Induce Cell Apopto
- Adv. Healthc. Mater. Nov 06 2024, | https://doi.org/10.1002/adhm.202403243
- 2024.11
- 바이오·의료융합
Lateral Piezoelectricity of Alzheimer‘s Aβ Aggregates
- Adv. Sci. Aug 19 2024, | https://doi.org/10.1002/advs.202406678
- 2024.08
- 바이오·의료융합
Gba1 E326K renders motor and non-motor symptoms with pathologic α-syn, tau and glial activation
- Brain Jul 08 2024, awae222 | https://doi.org/10.1093/brain/awae222
- 2024.07
- 생명과학
Revolutionizing Alzheimer‘s Treatment: Harnessing Human Serum Albumin for Targeted Drug Delivery and Therapy Advancements
- Ageing Res. Rev. Jun 18 2024, S1568-1637(24)00197-1 | https://doi.org/10.1016/j.arr.2024.102379
- 2024.06
Topical Nanoliposomal Collagen Delivery for Targeted Fibril Formation by Electrical Stimulation
- Adv. Healthc. Mater. May 25 2024, | https://doi.org/10.1002/adhm.202400693
- 2024.05
- 한무경(Max Planck Institute for Multidisciplinary Sciences)
Cryo-EM structures of lipidic fibrils of amyloid-β (1-40)
- Nat. Commun. Feb 13 2024, 15 (1) 1297 | https://doi.org/10.1038/s41467-023-43822-x
- 2024.02
- 생명과학
- Edward B. Lee(University of Pennsylvania School of Medicine)
Neurodegenerative Disease Tauopathies
- Annu. Rev. Pathol.-Mech. Dis. Oct 13 2023, | https://doi.org/10.1146/annurev-pathmechdis-051222-120750
- 2023.10