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'drug development' 에 대한 통합검색결과 754건입니다.
한빛사754건
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Conjugated polymer of Multi-arm-PEG and dimethylsiloxane (CPMD) for the effective transdermal delivery of deoxycholic acid for fat reduction
- Chem. Eng. J. Volume 505, 1 February 2025, 159405 | https://doi.org/10.1016/j.cej.2025.159405
- 2025.02
- 바이오·의료융합
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Spatiotemporal Dynamic Immunomodulation by Infection-Mimicking Gels Enhances Broad and Durable Protective Immunity Against Heterologous Viruses
- Adv. Sci. Jan 13 2025, | https://doi.org/10.1002/advs.202412116
- 2025.01
- 바이오·의료융합
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Molecular basis of neurosteroid and anticonvulsant regulation of TRPM3
- Nat. Struct. Mol. Biol. 14 January 2025 | https://doi.org/10.1038/s41594-024-01463-8
- 2025.01
- 생명과학
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Inhibition of GSK3β is synthetic lethal with FHIT loss in lung cancer by blocking homologous recombination repair
- Exp. Mol. Med. 06 January 2025 | https://doi.org/10.1038/s12276-024-01374-0
- 2025.01
- 생명과학
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Therapy-induced senescent cancer cells contribute to cancer progression by promoting ribophorin 1-dependent PD-L1 upregulation
- Nat. Commun. Jan 03 2025, 16 (1) 353 | https://doi.org/10.1038/s41467-024-54132-1
- 2025.01
- 의약학
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Structure-guided design and synthesis of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi
- Proc. Natl. Acad. Sci. USA Jan 07 2025, 122 (1) | https://doi.org/10.1073/pnas.2419883121
- 2025.01
- 바이오·의료융합
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Distinct modulation of calcium-activated chloride channel TMEM16A by drug-binding sites
- Proc. Natl. Acad. Sci. USA Dec 17 2024, 121 (51) | https://doi.org/10.1073/pnas.2314011121
- 2024.12
- 의약학
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Effect of electrochemical topology on detection sensitivity in MEA assay for drug-induced cardiotoxicity screening
- Biosens. Bioelectron. Dec 25 2024, 272 S0956-5663(24)01089-3 | https://doi.org/10.1016/j.bios.2024.117082
- 2024.12
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New insights into protein-protein interaction modulators in drug discovery and therapeutic advance
- Signal Transduct. Target. Ther. Dec 06 2024, 9 (1) 341 | https://doi.org/10.1038/s41392-024-02036-3
- 2024.12
- 의약학
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Thermally drawn porous sutures for controlled drug release using thermally induced phase separation
- Mater. Horizons Dec 11 2024, | https://doi.org/10.1039/d4mh01429d
- 2024.12
- 바이오·의료융합
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Liver organoids: Current advances and future applications for hepatology
- Clin. Mol. Hepatol. Dec 26 2024, | https://doi.org/10.3350/cmh.2024.1040
- 2024.12
- 의약학
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Channel-assembling tumor microenvironment on-chip for evaluating anticancer drug efficacy
- J. Control. Release Nov 24 2024, 377 S0168-3659(24)00775-2 | https://doi.org/10.1016/j.jconrel.2024.11.030
- 2024.11
- 바이오·의료융합
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SMYD family in cancer: epigenetic regulation and molecular mechanisms of cancer proliferation, metastasis, and drug resistance
- Exp. Mol. Med. 01 November 2024 | https://doi.org/10.1038/s12276-024-01326-8
- 2024.11
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Chemical-Driven Amyloid Clearance for Therapeutics and Diagnostics of Alzheimer‘s Disease
- Acc. Chem. Res. Nov 04 2024, | https://doi.org/10.1021/acs.accounts.4c00458
- 2024.11
- 의약학
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The intricate interactions between inflammasomes and bacterial pathogens: Roles, mechanisms, and therapeutic potentials
- Pharmacol. Ther. Nov 22 2024, S0163-7258(24)00176-1 | https://doi.org/10.1016/j.pharmthera.2024.108756
- 2024.11
- 의약학
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Scalable production of uniform and mature organoids in a 3D geometrically-engineered permeable membrane
- Nat. Commun. 31 October 2024 | https://doi.org/10.1038/s41467-024-53073-z
- 2024.10
- 바이오·의료융합
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Revisiting Pyrimidine-Embedded Molecular Frameworks to Probe the Unexplored Chemical Space for Protein-Protein Interactions
- Acc. Chem. Res. Oct 31 2024, | https://doi.org/10.1021/acs.accounts.4c00452
- 2024.10
- 생명과학
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Toxoplasma gondii macrophage migration inhibitory factor shows anti-Mycobacterium tuberculosis potential via AZIN1/STAT1 interaction
- Sci. Adv. Oct 25 2024, 10 (43) eadq0101 | https://doi.org/10.1126/sciadv.adq0101
- 2024.10
- 생명과학
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