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'data science' 에 대한 통합검색결과 1,111건입니다.

한빛사1,111건

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- 박주연(University of Texas at Austin)
Broadly neutralizing antibodies targeting pandemic GII.4 variants or seven GII genotypes of human norovirus
- Sci. Transl. Med. Mar 05 2025, 17 (788) | https://doi.org/10.1126/scitranslmed.ads8214
- 2025.03
Integrative transcriptogenomic analyses reveal a regulatory network of rice eating and cooking quality and unveil a role of alpha-globulin in modulati
- Plant Commun. February 19, 2025 | https://doi.org/10.1016/j.xplc.2025.101287
- 2025.02
- 생명과학
Zinah Hilal Khaleel

성균관대학교

1. Can you please briefly summarize the paper? This article details the design of a photoswitchable organic–peptide hybrids that self-associate into Ca 2+ -binding dimers when exposed to specific light wavelengths. This research highlights the potential of photoswitchable compounds to regulate complex equilibria, enabling the design of photoactive systems. These findings could lead to applications in various fields, demonstrating the ability to control protein behavior with light and targeted metal in this case calcium. 2. Can you please tell us the main difficulties you had in the laboratory work and how you overcame them? One of the main challenges I faced during my laboratory work was maintaining motivation, especially when progress felt slow or results were elusive. To overcome this, I learned to pause and reflect on how far I’d come, which helped me regain perspective and stay focused. Another difficulty was dealing with unexpected or unfavorable results. When experiments didn’t go as planned, I focused on being constructive evaluating whether the data could still be useful or identifying lessons to improve future work. There were also moments when I realized my research direction needed adjustment. Instead of seeing this as a setback, I embraced flexibility, adapted my approach, and found new ways to move forward. Finally, time management was a constant challenge. I worked on setting realistic goals, avoiding overloading my schedule, and accepting that some time pressure is inherent to the process. These strategies helped me stay productive and resilient throughout my PhD journey. 3. Please introduce your laboratory, university or organization to bio-researchers in Korea. I worked at the YH Protein Design Laboratory, a cutting-edge research group focused on protein engineering and design. The lab specializes in developing innovative approaches to understand, predict, and manipulate protein structures and functions, with applications rangin
- Proc. Natl. Acad. Sci. USA
- 2025.02.14
Kojo Eghan

안전성평가연구소

Our study focuses on evaluating the neurotoxic effects of 2-ethylhexanol, a chemical widely used in industrial applications, including plastic production, solvents, and fragrances. Despite its widespread presence in the environment, its potential impact on neurodevelopment has not been fully explored.
- J. Hazard. Mater.
- 2025.02.11
김주아

Chinese Academy of Sciences, Syracuse University

Before I explain this paper, I want to explain how I began doing this research. Metals are used commonly for dental, cardiovascular, and orthopedic applications, and traditional metals like titanium, cobalt-chromium, and stainless-steel alloys are still widely used in clinical settings due to their excellent biocompatibility and corrosion resistance.
- Bioact. Mater.
- 2024.12.23
- 김재연(Indiana University School of Medicine)
Estrogens and breast cancer
- Ann. Oncol. Nov 08 2024, S0923-7534(24)04880-4 | https://www.sciencedirect.com/science/article/pii/S0923753424048804
- 2024.11
Gyan Raj Koirala

성균관대학교

Real-time, continuous, and precise monitoring of vital signs in vivo is essential for detecting early signs of dysfunction of the organs and enabling timely intervention. For example, conditions like acute ischemic stroke constitute 87% of all stroke cases and post-surgical atrial fibrillation occurs in 20-50% of patients after cardiac surgery, underscore the critical need for predictive monitoring of these organs.
- Adv. Funct. Mater.
- 2024.11.15
고윤진

아주대학교 의과대학

Our study centers on hepatocellular carcinoma, which is the most prevalent form of liver cancer, ranking as the sixth most common and third most lethal cancer globally. Despite advancements in treatment modalities, the prognosis of HCC remains bleak due to its heterogeneity. Hence, we aimed to develop a novel gene set and AI tool to identify malignant hepatocytes in scRNA-seq data, thereby addressing the lack of existing biomarkers and computational tools and contributing to the discovery of therapeutic targets.
- J. Big Data
- 2024.10.30
장현준

University of Chicago

This study presents a diagnostic platform integrating field-effect transistor (FET) technology, a paper-based analytical device, and deep-learning (DL) based kinetic analysis to enhance quantitative biosensing performance. This platform demonstrated highly sensitive, rapid (
- ACS Nano
- 2024.10.02
Advance computational tools for multiomics data learning
- Biotechnol. Adv. Sep 07 2024, S0734-9750(24)00141-1 | https://doi.org/10.1016/j.biotechadv.2024.108447
- 2024.09
- 생명과학
Diagnostic Accuracy of Transient Elastography for Staging Liver Fibrosis in Autoimmune Liver Diseases: A Systematic Review and Meta-Analysis
- Clin. Mol. Hepatol. Aug 21 2024, | https://doi.org/10.3350/cmh.2024.0586
- 2024.08
- 의약학
박현

University of Illinois at Urbana-Champaign, 현 Absci

제 논문 “APACE (AlPhaFold2 and Advanced Computing as a sErvice)”는 생물리학, 인공지능, 그리고 슈퍼컴퓨터 기술을 종합한 연구입니다. 생물리학은 생물학과 물리학을 결합한 학문으로, 수학과 컴퓨터 알고리즘을 사용하여 분자의 성질을 분석하고 예측합니다. 예를 들어, 분자동력학은 분자들의 구조에서 에너지와 힘을 계산하여 분자의 움직임과 성질을 예측합니다.
- Proc. Natl. Acad. Sci. USA
- 2024.08.01
Sepsis Alert Systems, Mortality, and Adherence in Emergency Departments: A Systematic Review and Meta-Analysis
- JAMA Netw. Open Jul 01 2024, 7 (7) | https://doi.org/10.1001/jamanetworkopen.2024.22823
- 2024.07
- 의약학
Satya Priya Sharma

한림대학교

In this cross-sectional observational study, we have identified differential gut microbial biomarkers discriminating between cirrhosis patients with compensated and decompensated condition, that could predict cirrhosis severity progression and complications establishment. The systematic analysis approach of fecal microbial diversity at the species level revealed significant associations with conventional clinical markers.
- Clin. Mol. Hepatol.
- 2024.07.30
박준석

서울대학교 의과대학

안녕하십니까, 금년도 2024년도 2월에 서울대학교 의과대학을 졸업한 박준석이라고 합니다. 학부생 때 주제를 제안해서 시작했던 연구가, 상상했던 것을 훨씬 뛰어넘어 규모가 커져 공동 제1저자로 Science지에 논문 “GLP-1 Increases Preingestive Satiation via Hypothalamic Circuits in Mice and Humans”을 내게 되었음에 너무나도 큰 영광이고
- Science
- 2024.07.05
정영수

연세대학교

클론성 (clonality)란 한 세포에서부터 파생된, 동일한 성질을 갖고 있는 세포들을 이르는 집합적 명칭입니다. 유전체학적 정의는 DNA 정보가 동일한 세포 집단을 일컫습니다. 예를 들어, 어떤 암세포가 계속 증식한다면 그 세포들은 모두 DNA 정보가 동일하므로 같은 클론이라고 말할 수 있습니다. 그러다가 일정 세포들이 새로운 돌연변이를 얻은 후 또 증식한다면, 이는 부모-자식 간의 관계에 있는 서브클론 (subclone)이라고 할 수 있지요.
- Nucleic Acids Res.
- 2024.07.01
김장근

Weill Cornell Medicine

인터뷰를 통해 2024년 Nature Portfolio를 통해 출판된 Space Omics and Medical Atlas (SOMA) across orbits 논문 패키지를 소개할 수 있게 되어 기쁩니다. SOMA across orbits는 25개 이상 국가, 100개 이상 연구기관이 협력하여 우주비행에 의한 세포, 조직, 개체, 및 시스템적인 변화와 이의 대응방안에 대한 44개의 논문으로 구성되어 있습니다.
- Nat. Microbiol.
- 2024.06.20
손예은

Memorial Sloan Kettering Cancer Center/Weill Cornell Graduate School

Phospholipids are integral components of membranes that enable compartmentalization. Phosphatidylcholine and phosphatidylethanolamine, the two most common phospholipids in mammals that are essential for cellular proliferation, are synthesized de novo in cells from choline and ethanolamine, respectively.
- Nature
- 2024.05.24
- 왕승현(KAIST)
  Interview
- 이도헌(KAIST)
Community cohesion looseness in gene networks reveals individualized drug targets and resistance
- Brief. Bioinform. 15 April 2024 | https://doi.org/10.1093/bib/bbae175
- 2024.04
- 바이오·의료융합
Estimating the burden of vitiligo: a systematic review and modelling study
- Lancet Public Health Available online 26 March 2024 | https://doi.org/10.1016/S2468-2667(24)00026-4
- 2024.03
- 의약학