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'computational models' 에 대한 통합검색결과 118건입니다.

한빛사118건

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관련도순

- 백승빈(연세대학교, 현 Stanford University)
- 이인석(연세대학교)
Single-cell foundation models: bringing artificial intelligence into cell biology
- Exp. Mol. Med. 01 October 2025 | https://doi.org/10.1038/s12276-025-01547-5
- 2025.10
- 생명과학
- 장민혁(Johns Hopkins University)
  Interview
- 권형배(Johns Hopkins University)
Intercellular communication in the brain through a dendritic nanotubular network
- Science Oct 02 2025, 390 (6768) | https://doi.org/10.1126/science.adr7403
- 2025.10
- 생명과학
송우민

POSTECH

약물 독성은 임상 시험 실패와 시판 후 약물 철회의 주요 원인으로, 신약 개발 초기 단계에서 반드시 해결해야 할 핵심 과제입니다. 그러나 인간 세포주나 마우스 질환 모델이 인간의 독성 반응을 충분히 재현하지 못하는 경우가 종종 있습니다. 이로 인해 전임상 단계에서 안전하다고 평가된 약물이 실제 사람에게서는 예기치 못한 심각한 부작용을 나타내는 사례가 발생합니다.
- EBioMedicine
- 2025.10.30
Exploring the relationship between the androgen receptor and structural configuration of benzophenones: a combination of computational analysis and la
- Environ. Int. Volume 202, August 2025, 109632 | https://doi.org/10.1016/j.envint.2025.109632
- 2025.08
Albubody: an engineered scFv variant platform for site-specific drug conjugation and enhanced tumor efficacy
- J. Control. Release Aug 22 2025, S0168-3659(25)00777-1 | https://doi.org/10.1016/j.jconrel.2025.114165
- 2025.08
- 의약학
- 류재근(University of Massachusetts)
Food Hydrogels: Experimental and Theoretical Aspects Relating to their Formulation and Application
- Trends Food Sci. Technol. Available online 19 August 2025, 105242 | https://doi.org/10.1016/j.tifs.2025.105242
- 2025.08
- 이기영(Cornell University)
- 송정민(Cornell University)
Rifampin mediated decapsulation and enhanced bacterial clearance: a new mechanism of rifamycins
- EBioMedicine Jul 2025, 117 105787 S2352-3964(25)00231-2 | https://doi.org/10.1016/j.ebiom.2025.105787
- 2025.07
- 의약학
- Hanlee P. Ji(Stanford University School of Medicine)
Single cell and spatial alternative splicing analysis with Nanopore long read sequencing
- Nat. Commun. Published: 19 July 2025;16,6654(2025) | https://doi.org/10.1038/s41467-025-60902-2
- 2025.07
Genome-scale knockout simulation and clustering analysis of drug-resistant breast cancer cells reveal drug sensitization targets
- Proc. Natl. Acad. Sci. USA Jul 2025, 122 (26) | https://doi.org/10.1073/pnas.2425384122
- 2025.07
- 의약학
- David Joon Ho(국립암센터)
Artificial Intelligence-Driven Cancer Diagnostics: Enhancing Radiology and Pathology through Reproducibility, Explainability, and Multimodality
- Cancer Res. Jul 02 2025, 85 (13) | https://doi.org/10.1158/0008-5472.CAN-24-3630
- 2025.07
- 바이오·의료융합
나타니엘 카르페나

단국대학교

Our research aimed to address a long-standing challenge in hearing loss therapy: how to generate functional cochlear hair cells in the lab. These cells are responsible for converting sound vibrations into electrical signals that the brain can interpret. In humans, once these cells are damaged-due to aging, noise, or drugs-they do not regenerate.
- Theranostics
- 2025.04.28
Khandoker Asiqur Rahaman

한국과학기술연구원

This study was a multi-year collaboration and investigation into thymosin β4 (Tβ4) and its peptide metabolites. It focuses on their transformation from biological byproducts to bioactive agents with therapeutic relevance. Specifically, we identified and characterized Ac-Tβ1-17, a naturally derived Tβ4 metabolite, and revealed its dual functionality...
- Bioact. Mater.
- 2025.04.10
- 김필남(KAIST)
Engineering CAR-T Therapeutics for Enhanced Solid Tumor Targeting
- Adv. Mater. Jan 02 2025, | https://doi.org/10.1002/adma.202414882
- 2025.01
- 생명과학
Evaluating current status of network pharmacology for herbal medicine focusing on identifying mechanisms and therapeutic effects
- J. Adv. Res. Dec 25 2024, S2090-1232(24)00618-0 | https://doi.org/10.1016/j.jare.2024.12.040
- 2024.12
- 의약학
A normative framework dissociates need and motivation in hypothalamic neurons
- Sci. Adv. Nov 08 2024, 10 (45) | https://doi.org/10.1126/sciadv.ado1820
- 2024.11
- 바이오·의료융합
Easy and accurate protein structure prediction using ColabFold
- Nat. Protoc. 14 October 2024 | https://doi.org/10.1038/s41596-024-01060-5
- 2024.10
- 생명과학
고윤진

아주대학교 의과대학

Our study centers on hepatocellular carcinoma, which is the most prevalent form of liver cancer, ranking as the sixth most common and third most lethal cancer globally. Despite advancements in treatment modalities, the prognosis of HCC remains bleak due to its heterogeneity. Hence, we aimed to develop a novel gene set and AI tool to identify malignant hepatocytes in scRNA-seq data, thereby addressing the lack of existing biomarkers and computational tools and contributing to the discovery of therapeutic targets.
- J. Big Data
- 2024.10.30
- 허지현(Yale University)
  Interview
Language sentiment predicts changes in depressive symptoms
- Proc. Natl. Acad. Sci. USA Sep 24 2024, 121 (39) | https://doi.org/10.1073/pnas.2321321121
- 2024.09
- 임원필(Lehigh University, Bethlehem)
CHARMM-GUI Multicomponent Assembler for modeling and simulation of complex multicomponent systems
- Nat. Commun. 27 June 2024 | https://doi.org/10.1038/s41467-024-49700-4
- 2024.06
- 박현(University of Illinois at Urbana-Champaign, 현 Absci)
  Interview
APACE: AlphaFold2 and advanced computing as a service for accelerated discovery in biophysics
- Proc. Natl. Acad. Sci. USA June 24, 2024, 121 (27) | https://doi.org/10.1073/pnas.2311888121
- 2024.06
- 생명과학