한빛사1,373건

• • 김상연(가톨릭대학교 의과대학, 주식회사 네오나)

  • 나민정(가톨릭대학교 의과대학, 주식회사 네오나)

  • 남석우(가톨릭대학교 의과대학 병리학교실, 주식회사 네오나)

  The roles and mechanisms of coding and noncoding RNA variations in cancer

  • Exp. Mol. Med. 02 September 2024 | https://doi.org/10.1038/s12276-024-01307-x

  • 2024.09
  • 생명과학

• • 이지훈(전남대학교)

  Targeting the ATM pathway in cancer: Opportunities, challenges and personalized therapeutic strategies

  • Cancer Treat. Rev. Aug 05 2024, 129 S0305-7372(24)00136-1 | https://doi.org/10.1016/j.ctrv.2024.102808

  • 2024.08
• 

  성예원

  NIH

  We study cisplatin, which is a widely used and effective anticancer drug, but it has significant side effects, including ototoxicity (hearing loss) and nephrotoxicity (kidney injury), in pediatric and adult cancer patients. In this paper, we investigated the role of macrophages in cisplatin-induced hearing loss and kidney injury in mice.

  • Sci. Adv.
  • 2024.08.21

• • 최정윤(고려대학교 의과대학)

  ERBB2 amplification in gastric cancer: a genomic insight into ethnic disparities

  • JNCI-J. Natl. Cancer Inst. Jul 11 2024, djae147 | https://doi.org/10.1093/jnci/djae147

  • 2024.07

• • 이지훈(Princeton University)

  Distinct phases of cellular signaling revealed by time-resolved protein synthesis

  • Nat. Chem. Biol. Jul 08 2024, | https://doi.org/10.1038/s41589-024-01677-3

  • 2024.07
• 

  Javeria Zaheer

  한국원자력의학원

  Microplastics (MPs) are tiny particles (

  • J. Hazard. Mater.
  • 2024.07.29
• 

  최재혁

  Northwestern University

  In brief, we found that a chemical imbalance that mechanistically explains a cellular imbalance in patients with lupus (compared to healthy controls). Correcting this chemical imbalance appears to be a useful therapeutic approach for this disease.

  • Nature
  • 2024.07.15

• • 김원석(성균관대의대/삼성서울병원)

  Peripheral T-cell lymphoma: From biology to practice to the future

  • Cancer Treat. Rev. June 26, 2024 | https://doi.org/10.1016/j.ctrv.2024.102793

  • 2024.06
• 

  손예은

  Memorial Sloan Kettering Cancer Center/Weill Cornell Graduate School

  Phospholipids are integral components of membranes that enable compartmentalization. Phosphatidylcholine and phosphatidylethanolamine, the two most common phospholipids in mammals that are essential for cellular proliferation, are synthesized de novo in cells from choline and ethanolamine, respectively.

  • Nature
  • 2024.05.24

• • 윤인수(서울시립대학교)

  • 김의진(서울시립대학교)

  • 송유석(서울시립대학교)

  • 박태수(서울시립대학교)

  • 이동성(서울시립대학교)

  3C methods in cancer research: recent advances and future prospects

  • Exp. Mol. Med. Apr 25 2024, | https://doi.org/10.1038/s12276-024-01236-9

  • 2024.04
  • 생명과학

• • 왕승현(KAIST)

    Interview

  • 이도헌(KAIST)

  Community cohesion looseness in gene networks reveals individualized drug targets and resistance

  • Brief. Bioinform. 15 April 2024 | https://doi.org/10.1093/bib/bbae175

  • 2024.04
  • 바이오·의료융합

• • 이민학(경희대학교 약학대학)

  • 이바다(경희대학교 약학대학)

  • 김이랑(온코크로스, 경희대 규제과학과)

  • 최진우(경희대학교 약학대학)

  Transcriptome-based deep learning analysis identifies drug candidates targeting protein synthesis and autophagy for the treatment of muscle wasting di

  • Exp. Mol. Med. 01 April 2024 | https://doi.org/10.1038/s12276-024-01189-z

  • 2024.04
  • 의약학
• 

  이재은

  서울대학교

  텔로미어는 세포의 염색체 끝단을 보호하기 위해 존재하는 방패이자, 세포 분열 횟수를 제한하여 암화 되는 것을 막는 중요한 역할을 합니다. 무한한 세포증식을 하는 암세포는 이러한 텔로미어의 한계를 극복하는 것이 필수적인데 약 10-15%의 암세포는 텔로머라아제 (telomerase)라는 효소 대신 재조합으로 텔로미어를 합성합니다.

  • Nucleic Acids Res.
  • 2024.04.18

• • 박정현(National Cancer Institute, NIH)

  Pathways and mechanisms of CD4+CD8αα+ intraepithelial T cell development

  • Trends Immunol. Available online 20 March 2024 | https://doi.org/10.1016/j.it.2024.02.006

  • 2024.03
  • 생명과학

• • 임종수(서울시립대학교)

  • 박찬호(서울시립대학교)

  • 이동성(서울시립대학교)

  Advances in single-cell omics and multiomics for high-resolution molecular profiling

  • Exp. Mol. Med. Mar 05 2024, | https://doi.org/10.1038/s12276-024-01186-2

  • 2024.03
  • 생명과학
• 

  Haribalan Perumalsamy

  한양대학교

  In this study, we overcome some of the traditional approaches to analyze the toxicity of nanomaterials that are used for various biomedical applications. In particular, many approaches on toxicity assessment of AgNPs have been previously studied using in vitro or in vivo analysis. However, there has been limited study on ex vivo toxicity evaluation, notably on human primary peripheral blood mononuclear cells (hPBMCs), which could be a feasible alternative approach to study leukocytes population.

  • J. Nanobiotechnol.
  • 2024.03.22

• • 최운영(Johns Hopkins University School of Medicine)

  Tumour tissue-derived small extracellular vesicles reflect molecular subtypes of bladder cancer

  • J. Extracell. Vesicles Feb 2024, 13 (2) | https://doi.org/10.1002/jev2.12402

  • 2024.02

• • 김예진(University of Texas Health Science Center at Houston)

  CancerGPT for few shot drug pair synergy prediction using large pretrained language models

  • npj Digit. Med. 19 February 2024;7;40(2024) | https://doi.org/10.1038/s41746-024-01024-9

  • 2024.02

• • 최재혁(Northwestern University)

    Interview

  Naturally occurring T cell mutations enhance engineered T cell therapies

  • Nature Feb 07 2024, | https://doi.org/10.1038/s41586-024-07018-7

  • 2024.02
• 

  이효형

  서울대학교, Icahn School of Medicine at Mount Sinai

  Psoriasis is a chronic, T-cell-mediated inflammatory skin disease with a Th17-skewed immune phenotype. Regulatory T cells (Tregs) play a key role in suppressing the inflammatory immune response and inducing immune homeostasis and self-tolerance. While the role of Tregs in the pathogenesis of psoriasis has been proposed, the exact mechanisms of action and the molecular characterization of skin-homing psoriatic Tregs has not yet been well explored.

  • EBioMedicine
  • 2024.02.16