Tumor heterogeneity > 통합검색

통합검색

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1Tumor heterogeneity

'Tumor heterogeneity' 에 대한 통합검색결과 169건입니다.

한빛사169건

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Microfabricated Organ-Specific Models of Tumor Microenvironments
- Annu. Rev. Biomed. Eng. May 2025; Vol. 27:307-333 | https://doi.org/10.1146/annurev-bioeng-110222-103522
- 2025.05
- 바이오·의료융합
Liquid biopsy for cancer immunotherapy: Biomarkers to predict and monitor response upon immune checkpoint blockade
- Coord. Chem. Rev. Available online 5 May 2025 | https://doi.org/10.1016/j.ccr.2025.216767
- 2025.05
- 바이오·의료융합
Enhancing the bystander effect of antibody-drug conjugate by using a novel caspase-3 cleavable peptide linker to overcome tumor heterogeneity
- J. Control. Release Available online 15 April 2025 | https://doi.org/10.1016/j.jconrel.2025.113738
- 2025.04
- 의약학
- 김현정(KAIST, 고려대학교 의과대학)
- 이정호(KAIST, 소바젠)
Precancerous Cells Initiate Glioblastoma Evolution and Contribute to Intratumoral Heterogeneity
- Cancer Discov. Apr 16 2025, | https://doi.org/10.1158/2159-8290.CD-24-0234
- 2025.04
- 의약학
- 김석영(Princess Maxima Center for Pediatric Oncology)
The future of tumor organoids in precision therapy
- Trends Cancer Apr 03 2025, S2405-8033(25)00073-1 | https://doi.org/10.1016/j.trecan.2025.03.005
- 2025.04
- 의약학
- 엄정현(연세대학교 의과대학)
Genomic and Single-Cell Analyses Characterize Patient-Derived Tumor Organoids to Enable Personalized Therapy for Head and Neck Squamous Cell Carcinoma
- Cancer Res. Apr 22 2025, | https://doi.org/10.1158/0008-5472.CAN-24-2850
- 2025.04
- 오주현(Massachusetts General Hospital/Harvard Medical School)
Spatial analysis identifies DC niches as predictors of pembrolizumab therapy in head and neck squamous cell cancer
- Cell Rep. Med. April 30, 2025 | https://doi.org/10.1016/j.xcrm.2025.102100
- 2025.04
- 생명과학
Bioprinted Patient-Derived Organoid Arrays Capture Intrinsic and Extrinsic Tumor Features for Advanced Personalized Medicine
- Adv. Sci. Mar 28 2025, | https://doi.org/10.1002/advs.202407871
- 2025.03
A Neuroimmune-Oncology Microphysiological Analysis Platform (NEO-MAP) for Evaluating Astrocytic Scar Formation and Microgliosis in Glioblastoma Microe
- Adv. Healthc. Mater. Mar 12 2025, | https://doi.org/10.1002/adhm.202404821
- 2025.03
- 바이오·의료융합
윤재원

한양대학교

미분화 T 세포(naive T cell)는 흉선에서 성숙한 후 항원을 만나 활성화되기 이전 단계의 T 세포입니다. 이들은 effector marker나 effector molecule을 발현하지 않기 때문에, 질병의 치료 및 병인 기전을 연구하는 측면에서 상대적으로 큰 주목을 받지 못했으며, 하나의 동질적인 quiescent한 군집으로 여겨져 왔습니다. 그러나 흉선에서 부여되는 self-antigen affinity에 따른 발달 단계에서의 이질성(heterogeneity)에 대한 연구와 더불어, ...
- Nat. Commun.
- 2025.03.05
Th1-poised naive CD4 T cell subpopulation reflects anti-tumor immunity and autoimmune disease
- Nat. Commun. Published: 25 February 2025 | https://doi.org/10.1038/s41467-025-57237-3
- 2025.02
- 생명과학
Determinants of Response to Sequential Pembrolizumab with Trastuzumab Plus Platinum/5FU in HER2-positive Gastric Cancer: A Phase II Chemoimmunotherapy
- Clin. Cancer Res. February 17 2025 | https://doi.org/10.1158/1078-0432.CCR-24-3528
- 2025.02
- 의약학
- 김석영(Princess Maxima Center for Pediatric Oncology)
Organoid drug profiling identifies methotrexate as a therapy for SCCOHT, a rare pediatric cancer
- Sci. Adv. Feb 28 2025, 11 (9) eadq1724 | https://doi.org/10.1126/sciadv.adq1724
- 2025.02
- 생명과학
Hybrid lipid nanoparticles with tumor antigen-primed dendritic cell membranes for post-surgical tumor immunotherapy
- J. Control. Release Jan 10 2025, S0168-3659(25)00029-X | https://doi.org/10.1016/j.jconrel.2025.01.027
- 2025.01
- 의약학
- 김필남(KAIST)
Engineering CAR-T Therapeutics for Enhanced Solid Tumor Targeting
- Adv. Mater. Jan 02 2025, | https://doi.org/10.1002/adma.202414882
- 2025.01
- 생명과학
Prediction of Patient Drug Response via 3D Bioprinted Gastric Cancer Model Utilized Patient-Derived Tissue Laden Tissue-Specific Bioink
- Adv. Sci. 02 January 2025 | https://doi.org/10.1002/advs.202411769
- 2025.01
- 바이오·의료융합
- 정효빈(연세대학교)
Single-cell multiomics analysis reveals dynamic clonal evolution and targetable phenotypes in acute myeloid leukemia with complex karyotype
- Nat. Genet. 25 November 2024 | https://doi.org/10.1038/s41588-024-01999-x
- 2024.11
- 김하린(서울대학교, Stanford University, 국민대학교)
- 변영로(서울대학교)
Synergistic anticancer immunity in metastatic triple-negative breast cancer through an in situ amplifying Peptide-Drug Conjugate
- J. Control. Release Volume 375 , November 2024, Pages 681-697 | https://doi.org/10.1016/j.jconrel.2024.07.074
- 2024.11
- 의약학
- 이은미(Princeton University)
Deciphering normal and cancer stem cell niches by spatial transcriptomics: opportunities and challenges
- Genes Dev. Nov 04 2024, | https://doi.org/10.1101/gad.351956.124
- 2024.11
- 생명과학
고윤진

아주대학교 의과대학

Our study centers on hepatocellular carcinoma, which is the most prevalent form of liver cancer, ranking as the sixth most common and third most lethal cancer globally. Despite advancements in treatment modalities, the prognosis of HCC remains bleak due to its heterogeneity. Hence, we aimed to develop a novel gene set and AI tool to identify malignant hepatocytes in scRNA-seq data, thereby addressing the lack of existing biomarkers and computational tools and contributing to the discovery of therapeutic targets.
- J. Big Data
- 2024.10.30