통합검색
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'Targeted protein degradation' 에 대한 통합검색결과 81건입니다.
한빛사81건
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Advanced MicroRNA delivery for lung inflammatory therapy: surfactant protein A controls cellular internalisation and degradation of extracellular vesi
- Thorax Dec 04 2024, thorax-2024-221793 | https://doi.org/10.1136/thorax-2024-221793
- 2024.12
- 생명과학
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Impaired chaperone-mediated autophagy leads to abnormal SORT1 (sortilin 1) turnover and CES1-dependent triglyceride hydrolysis
- Autophagy 29 Nov 2024 | https://doi.org/10.1080/15548627.2024.2435234
- 2024.11
- 의약학
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Designed endocytosis-inducing proteins degrade targets and amplify signals
- Nature Sep 25 2024, | https://doi.org/10.1038/s41586-024-07948-2
- 2024.09
- 바이오·의료융합
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Phosphorylation of the selective autophagy receptor TAX1BP1 by TBK1 and IKBKE/IKKi promotes Atg8-family protein-dependent clearance of MAVS aggregates
- Autophagy Aug 28 2024, | https://doi.org/10.1080/15548627.2024.2394306
- 2024.08
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Disruption of the ZFP574?THAP12 complex suppresses B cell malignancies in mice
- Proc. Natl. Acad. Sci. USA July 24, 2024 | https://doi.org/10.1073/pnas.2409232121
- 2024.07
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Light-Triggered PROTAC Nanoassemblies for Photodynamic IDO Proteolysis in Cancer Immunotherapy
- Adv. Mater. Jun 19 2024, | https://doi.org/10.1002/adma.202405475
- 2024.06
- 바이오·의료융합
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Overcoming BRAF and CDK4/6 inhibitor resistance by inhibiting MAP3K3-dependent protection against YAP lysosomal degradation
- Exp. Mol. Med. Apr 16 2024, | https://doi.org/10.1038/s12276-024-01210-5
- 2024.04
- 의약학
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Targeted protein degradation directly engaging lysosomes or proteasomes
- Chem. Soc. Rev. Feb 19 2024, | https://doi.org/10.1039/d3cs00344b
- 2024.02
- 의약학
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Cell Membrane as A Promising Therapeutic Target: From Materials Design to Biomedical Applications
- Angew. Chem.-Int. Edit. Feb 19 2024, | https://doi.org/10.1002/anie.202400249
- 2024.02
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Targeted degradation of SNCA/α-synuclein aggregates in neurodegeneration using the AUTOTAC chemical platform
- Autophagy Nov 01 2023, | https://doi.org/10.1080/15548627.2023.2274711
- 2023.11
- 생명과학
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Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras
- Science Oct 20 2023, 382 (6668) | https://doi.org/10.1126/science.adf6249
- 2023.10
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Targeted degradation of α-synuclein aggregates in Parkinson’s disease using the AUTOTAC technology
- Mol. Neurodegener. 2023 Jun 24;18(1):41 | https://doi.org/10.1186/s13024-023-00630-7
- 2023.06
- 생명과학
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Chemical Knockdown of Phosphorylated p38 Mitogen-Activated Protein Kinase (MAPK) as a Novel Approach for the Treatment of Alzheimer′s Disease
- ACS Central Sci. Publication Date:March 1, 2023 | https://doi.org/10.1021/acscentsci.2c01369
- 2023.03
- 의약학
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Pseudoknot-targeting Cas13b combats SARS-CoV-2 infection by suppressing viral replication
- Mol. Ther. 2023 Mar 21;S1525-0016(23)00139-9 | https://doi.org/10.1016/j.ymthe.2023.03.018
- 2023.03
- 생명과학
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Targeted Degradation of PRC1 Components, BMI1 and RING1B, via a Novel Protein Complex Degrader Strategy
- Adv. Sci. First published: 03 February 2023 | https://doi.org/10.1002/advs.202205573
- 2023.02
- 의약학
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Targeted Protein Upregulation of STING for Boosting the Efficacy of Immunotherapy
- Angew. Chem.-Int. Edit. 2023 Feb 24;e202300978 | https://doi.org/10.1002/anie.202300978
- 2023.02
- 생명과학
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Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells
- Cancer Cell Published:March 09, 2023 | https://doi.org/10.1016/j.ccell.2023.02.010
- 2023.02
- 생명과학
