한빛사79건

• • 이상희(Northwestern University)

  • 고민준(Northwestern University)

  • 김동현(Northwestern University)

  Cryo-Nanocatalyst Enhances Therapeutic Efficacy of Cryo-Immunotherapy through Necroptosis and Local Delivery of Programmed Death-Ligand 1 Inhibitors

  • ACS Nano Aug 22 2024, | https://doi.org/10.1021/acsnano.4c05809

  • 2024.08
  • 바이오·의료융합

• • 이장순(University of Hawai'I Cancer Center)

  • 임석아(서울대학교 의과대학)

  The DNA repair pathway as a therapeutic target to synergize with trastuzumab deruxtecan in HER2-targeted antibody-drug conjugate-resistant HER2-overex

  • J. Exp. Clin. Cancer Res. Aug 21 2024, 43 (1) 236 | https://doi.org/10.1186/s13046-024-03143-3

  • 2024.08

• • 박병선(한국과학기술연구원)

  • 김택훈(한국과학기술연구원)

  Polyamine and EIF5A hypusination downstream of c-Myc confers targeted therapy resistance in BRAF mutant melanoma

  • Mol. Cancer Jul 04 2024, 23 (1) | https://doi.org/10.1186/s12943-024-02031-w

  • 2024.07
  • 생명과학

• • 권민철(Janssen R&D)

  Preclinical efficacy of potent and selective menin-KMT2A inhibitor JNJ-75276617 in KMT2A- and NPM1-altered leukemias

  • Blood Jun 21 2024, blood.2023022480 | https://doi.org/10.1182/blood.2023022480

  • 2024.06

• • 조영진(아주대학교)

    Interview

  • 윤현진(아주대학교)

  Exploring the therapeutic potential of endolysin CD27L_EAD against Clostridioides difficile infection

  • Int. J. Antimicrob. Agents May 27 2024, S0924-8579(24)00140-7 | https://doi.org/10.1016/j.ijantimicag.2024.107222

  • 2024.05
  • 바이오·의료융합

• • 김진성(이화여자대학교, 고려대학교)

  • 심만규(한국과학기술연구원 (KIST))

  • 김광명(이화여자대학교 약학대학)

  Cancer cell-specific and pro-apoptotic SMAC peptide-doxorubicin conjugated prodrug encapsulated aposomes for synergistic cancer immunotherapy

  • J. Nanobiotechnol. Mar 13 2024, 22 (1) 109 | https://doi.org/10.1186/s12951-024-02314-w

  • 2024.03
  • 바이오·의료융합

• • 윤지훈(연세대학교 의과대학, 서울대학교병원)

    Interview

  • 장동건(연세대학교 의과대학)

  • 조성규(연세대학교 의과대학)

  • 이재면(연세대학교 의과대학)

  • 김상헌(한양대학교 의과대학)

  • 이민구(연세대학교)

  Synergistic toxicity with copper contributes to NAT2-associated isoniazid toxicity

  • Exp. Mol. Med. Mar 01 2024, | https://doi.org/10.1038/s12276-024-01172-8

  • 2024.03

• • 이민지(네오이뮨텍)

    Interview

  • 최동훈(네오이뮨텍)

  rhIL-7-hyFc and hIL-2/TCB2c combination promotes an immune-stimulatory tumor microenvironment that improves antitumor efficacy of checkpoint inhibitor

  • J. Immunother. Cancer Mar 12 2024, 12 (3) e008001 | https://doi.org/10.1136/jitc-2023-008001

  • 2024.03
  • 생명과학

• • 이은지(연세대학교 의과대학)

  • 윤미란(연세대학교 의과대학 의생명과학부)

  • 조병철(연세대학교 의과대학)

  Discovery of a novel potent EGFR inhibitor against EGFR activating mutations and on-target resistance in NSCLC

  • Clin. Cancer Res. Feb 08 2024, | https://doi.org/10.1158/1078-0432.CCR-23-2951

  • 2024.02
  • 의약학

• • 김태곤(Vanderbilt University Medical Center)

  PD-1H/VISTA mediates immune evasion in acute myeloid leukemia

  • J. Clin. Invest. Dec 07 2023, e164325 | https://doi.org/10.1172/JCI164325

  • 2023.12

• • 신홍식(성균관대학교)

    Interview

  • 김소현(성균관대학교)

  • 임용택(성균관대학교)

  Molecular Masking of Synthetic Immunomodulator Evokes Antitumor Immunity with Reduced Immune Tolerance and Systemic Toxicity by Temporal Activity Reco

  • Adv. Mater. Oct 30 2023, | https://doi.org/10.1002/adma.202309039

  • 2023.10
  • 바이오·의료융합

• • 이경관(한국생명공학연구원, 경희대학교)

  • 이창수(한국생명공학연구원, UST)

  • 이상천(경희대학교)

  Ferritin-nanocaged copper arsenite minerals with oxidative stress-amplifying activity for targeted cancer therapy

  • J. Control. Release Vol 361, Sep 2023, Pages 350-360 | https://doi.org/10.1016/j.jconrel.2023.07.050

  • 2023.09
  • 바이오·의료융합

• • 구현(University of Pennsylvania)

  Iron oxide nanozymes stabilize stannous fluoride for targeted biofilm killing and synergistic oral disease prevention

  • Nat. Commun. Sep 29 2023, 14 (1) 6087 | https://doi.org/10.1038/s41467-023-41687-8

  • 2023.09

• • 원솔찬(서울대학교 의과대학)

    Interview

  • 이창진(에스엘바이젠)

  • 배서윤(POSTECH)

  • 이재민(에스엘바이젠, POSTECH)

  • 이태룡(에스엘바이젠)

  • 이동섭(서울대학교)

  • 고용송(POSTECH)

  Mass-produced gram-negative bacterial outer membrane vesicles activate cancer antigen-specific stem-like CD8+ T cells which enables an effective combi

  • J. Extracell. Vesicles 2023 Aug;12(8):e12357 | https://doi.org/10.1002/jev2.12357

  • 2023.08
  • 생명과학

• • 김은영(조선대학교)

  • S. Dinesh Kumar(조선대학교)

  • 방정규(한국기초과학지원연구원(KBSI))

  • 조성진(충북대학교)

  • 신송엽(조선대학교)

  Evaluation of deoxythymidine-based cationic amphiphiles as antimicrobial, antibiofilm, and anti-inflammatory agents

  • Int. J. Antimicrob. Agents Available online 5 July 2023, 106909 | https://doi.org/10.1016/j.ijantimicag.2023.106909

  • 2023.07
  • 의약학

• • 신유선(중앙대학교)

  • 임채민(중앙대학교)

  • 오경택(중앙대학교)

  RNA-Seq-guided triple-combination nano-system of gold nanocluster, quercetin, and docetaxel for ultimate synergistic photothermal-chemotherapy against

  • Nano Today Volume 50, June 2023, 101862 | https://doi.org/10.1016/j.nantod.2023.101862

  • 2023.06

• • 김도윤(서울시립대학교)

  • 박건우(건국대학교)

  • 박정태(건국대학교)

  • 최인희(서울시립대학교)

  Photoactive MOF-Derived Bimetallic Silver and Cobalt Nanocomposite with Enhanced Antibacterial Activity

  • ACS Appl. Mater. Interfaces 2023 May 17;15(19):22903-22914 | https://doi.org/10.1021/acsami.3c01529

  • 2023.05
  • 바이오·의료융합

• • 김형진(State University of New York, Stony Brook)

  Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe

  • Nucleic Acids Res. 2023 May 5;gkad36 | https://doi.org/10.1093/nar/gkad363

  • 2023.05
  • 생명과학

• • Ying Zhang(전남대학교 의과대학)

  • 홍영진(전남대학교 의과대학)

  • 민정준(전남대학교 의과대학)

  Synergistic cancer immunotherapy utilizing programmed Salmonella typhimurium secreting heterologous flagellin B conjugated to interleukin-15 proteins

  • Biomaterials 2023 Apr 27;298:12213 | https://doi.org/10.1016/j.biomaterials.2023.122135

  • 2023.04
  • 의약학

• • Fazlurrahman Khan(부경대학교)

  • 정금재(부경대학교)

  • 김영목(부경대학교)

  Surface adherence and vacuolar internalization of bacterial pathogens to the Candida spp. cells: Mechanism of persistence and propagation

  • J. Adv. Res. 2022 Dec 23;S2090-1232(22)00292-2 | https://doi.org/10.1016/j.jare.2022.12.013

  • 2022.12