한빛사1,093건

• • 변완기(서울대학교)

    Interview

  • 박승범(서울대학교)

  Broad-Spectrum Antiviral Agents against SARS-CoV-2 Variants Inhibit the Conserved Viral Protein Nsp1-RNA Interaction

  • Angew. Chem.-Int. Edit. Aug 12 2024, | https://doi.org/10.1002/anie.202405472

  • 2024.08
  • 생명과학

• • 이종원(한국과학기술연구원(KIST))

  • 양유수(한국과학기술연구원(KIST))

  • 김선화(한국과학기술연구원(KIST))

  Dual-Action Protein-siRNA Conjugates for Targeted Disruption of CD47-Signal Regulatory Protein α Axis in Cancer Therapy

  • ACS Nano Aug 08 2024, | https://doi.org/10.1021/acsnano.4c06471

  • 2024.08
  • 바이오·의료융합

• • 김연정(The Ohio State University)

  HOS15-mediated turnover of PRR7 enhances freezing tolerance

  • New Phytol. Aug 19 2024, | https://doi.org/10.1111/nph.20062

  • 2024.08
  • 생명과학

• • 이소연(차의과학대학교)

  • 이기영(차의과학대학교)

  Effector Binding Sequentially Alters KRAS Dimerization on the Membrane: New Insights Into RAS-Mediated RAF Activation

  • Adv. Sci. Aug 13 2024, | https://doi.org/10.1002/advs.202401530

  • 2024.08

• • 한정필(서울대학교)

  • 남유리(KAIST)

  • 이해신(KAIST)

  • 염수청(서울대학교)

  Polyphenol-Enabled 2D Nanopatch for Enhanced Nasal Mucoadhesion and Immune Activation

  • Nano Lett. Aug 09 2024, | https://doi.org/10.1021/acs.nanolett.4c03228

  • 2024.08
  • 바이오·의료융합

• • 한혜숙(고려대학교)

  • 최병훈(고려대학교)

  • 구승회(고려대학교)

  Regulation of hepatic lipogenesis by asymmetric arginine methylation

  • Metab.-Clin. Exp. Aug 2024, 157 S0026-0495(24)00165-3 | https://doi.org/10.1016/j.metabol.2024.155938

  • 2024.08
  • 생명과학
• 

  변완기

  서울대학교

  코로나19 (COVID-19)는 2020년부터 전 세계를 강타하여 공중보건은 물론 사회, 경제에도 큰 영향을 미쳤습니다. 코로나19 팬데믹이 종식된 후에도 SARS-CoV-2 바이러스는 지속적으로 변이를 일으키며 인류의 건강에 위협을 가하고 있습니다. 하지만 SARS-CoV-2와 같은 RNA 바이러스는 변이가 잦아, 스파이크(spike) 단백질을 중점적으로 표적하여 개발한 기존의 백신과 치료제의 효과를 저하시킬 위험이 큽니다.

  • Angew. Chem.-Int. Edit.
  • 2024.08.19

• • 조민정(성균관대학교 의과대학)

  • 권영대(성균관대학교 의과대학)

  Reduced dynamicity and increased high-order protein assemblies in dense fibrillar component of the nucleolus under cellular senescence

  • Redox Biol. Jul 25 2024, 75 S2213-2317(24)00257-X | https://doi.org/10.1016/j.redox.2024.103279

  • 2024.07
  • 의약학

• • 이환규(단국대학교)

  Hydrodynamics and Aggregation of Nanoparticles with Protein Corona: Effects of Protein Concentration and Ionic Strength

  • Small Jul 31 2024, | https://doi.org/10.1002/smll.202403913

  • 2024.07
  • 바이오·의료융합

• • 박경진(Massachusetts Institute of Technology)

  Pentaphosphorylation via the Anhydride of Dihydrogen Pentametaphosphate: Access to Nucleoside Hexa- and Heptaphosphates and Study of Their Interaction

  • ACS Central Sci. Jul 24 2024, 10 (7) | https://doi.org/10.1021/acscentsci.4c00835

  • 2024.07

• • 최정현(McGill University)

  Repression of mRNA translation initiation by GIGYF1 via disrupting the eIF3-eIF4G1 interaction

  • Sci. Adv. Jul 19 2024, 10 (29) | https://doi.org/10.1126/sciadv.adl5638

  • 2024.07

• • 김정원(POSTECH)

  • 서민채(POSTECH)

  • 김종민(POSTECH)

  START: A Versatile Platform for Bacterial Ligand Sensing with Programmable Performances

  • Adv. Sci. Jul 29 2024, | https://doi.org/10.1002/advs.202402029

  • 2024.07
  • 생명과학

• • 최윤정(시프트바이오, 고려대학교)

  • 김성아(고려대학교, 한국과학기술연구원)

  • 남기훈(시프트바이오, 고려대학교)

  • 권민수(울산대학교 의과대학)

  • 김인산(고려대학교, 한국과학기술연구원)

  Novel insights into paclitaxel‘s role on tumor-associated macrophages in enhancing PD-1 blockade in breast cancer treatment

  • J. Immunother. Cancer Jul 15 2024, 12 (7) e008864 | https://jitc.bmj.com/content/12/7/e008864

  • 2024.07
  • 의약학

• • 김승현(Delft University of Technology, 이화여자대학교)

  • 주철민(Delft University of Technology, 이화여자대학교)

  iMAX FRET (Information Maximized FRET) for Multipoint Single-Molecule Structural Analysis

  • Nano Lett. Jul 08 2024, | https://doi.org/10.1021/acs.nanolett.4c00447

  • 2024.07
  • 생명과학

• • 김우균(University of Georgia)

  Effects of methionine supplementation in a reduced protein diet on growth performance, oxidative status, intestinal health, oocyst shedding, and methi

  • J. Anim. Sci. Biotechnol. Jun 10 2024, 15 (1) | https://doi.org/10.1186/s40104-024-01041-4

  • 2024.06

• • 구진모(University of Kentucky, 현 Universityof California, Riverside)

  StaufenC facilitates utilization of the ERAD pathway to transport dsRNA through the endoplasmic reticulum to the cytosol

  • Proc. Natl. Acad. Sci. USA Jun 25 2024, 121 (26) | https://doi.org/10.1073/pnas.2322927121

  • 2024.06

• • 권민철(Janssen R&D)

  Preclinical efficacy of potent and selective menin-KMT2A inhibitor JNJ-75276617 in KMT2A- and NPM1-altered leukemias

  • Blood Jun 21 2024, blood.2023022480 | https://doi.org/10.1182/blood.2023022480

  • 2024.06

• • 최지연(National Cancer Institute)

  High-throughput characterization of functional variants highlights heterogeneity and polygenicity underlying lung cancer susceptibility

  • Am. J. Hum. Genet. Jun 17 2024, S0002-9297(24)00184-8 | https://doi.org/10.1016/j.ajhg.2024.05.021

  • 2024.06
  • 생명과학

• • Divya Shastri(중앙대학교)

  • Vinit Raj(중앙대학교)

  • 이상길(중앙대학교 약학대학)

  Revolutionizing Alzheimer‘s Treatment: Harnessing Human Serum Albumin for Targeted Drug Delivery and Therapy Advancements

  • Ageing Res. Rev. Jun 18 2024, S1568-1637(24)00197-1 | https://doi.org/10.1016/j.arr.2024.102379

  • 2024.06

• • 김동훈(Johns Hopkins University School of Medicine, 현 동아대학교 의과대학)

  • 고한석(Johns Hopkins University School of Medicine)

  Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein

  • Nat. Commun. May 31 2024, 15 (1) 4663 | https://doi.org/10.1038/s41467-024-49016-3

  • 2024.05
  • 생명과학