한빛사218건

• • 전희진(울산과학기술원)

  • 여미래(울산과학기술원)

  • 전준표(울산과학기술원)

  • 박성호(울산과학기술원)

  • 김은희(울산과학기술원)

  • 강세병(울산과학기술원)

  CD13-targeting and TRAIL-displaying protein nanoparticles effectively induce apoptotic cell death of acute myeloid leukemia, prolonging survival in mo

  • Nano Today Available online 4 September 2024 | https://doi.org/10.1016/j.nantod.2024.102474

  • 2024.09
  • 생명과학

• • 정예희(이화여자대학교 약학대학)

  • 신수민(이화여자대학교)

  • 서원효(이화여자대학교)

  • 이혁진(이화여자대학교 약학대학)

  Engineered lipid nanoparticles enable therapeutic gene silencing of GTSE1 for the treatment of liver fibrosis

  • J. Control. Release Aug 22 2024, 374 S0168-3659(24)00551-0 | https://doi.org/10.1016/j.jconrel.2024.08.012

  • 2024.08
  • 의약학

• • 류지연(Harvard Medical School, Brigham and Women’s Hospital)

  • 류일환(국민대학교)

  Brain-targeted intranasal delivery of protein-based gene therapy for treatment of ischemic stroke

  • Theranostics 2024.08.12 ;14(12):4773-4786 | https://www.thno.org/v14p4773

  • 2024.08
  • 바이오·의료융합

• • 이종원(한국과학기술연구원(KIST))

  • 양유수(한국과학기술연구원(KIST))

  • 김선화(한국과학기술연구원(KIST))

  Dual-Action Protein-siRNA Conjugates for Targeted Disruption of CD47-Signal Regulatory Protein α Axis in Cancer Therapy

  • ACS Nano Aug 08 2024, | https://doi.org/10.1021/acsnano.4c06471

  • 2024.08
  • 바이오·의료융합

• • 김경란(한국과학기술연구원)

  • 강지희(가천대학교 약학대학)

  • 고영탁(가천대학교 약학대학)

  • 안대로(한국과학기술연구원, UST)

  Systemic Brain Delivery of Oligonucleotide Therapeutics Enhanced by Protein Corona-Assisted DNA Cubes

  • Small Methods Aug 02 2024, | https://doi.org/10.1002/smtd.202400902

  • 2024.08
  • 의약학

• • 곽기정(University of Maryland)

  • 석정수(University of Maryland, Johns Hopkins University School of Medicine)

  Brain Nucleic Acid Delivery and Genome Editing via Focused Ultrasound-Mediated Blood-Brain Barrier Opening and Long-Circulating Nanoparticles

  • ACS Nano Aug 22 2024, | https://doi.org/10.1021/acsnano.4c05270

  • 2024.08
  • 바이오·의료융합

• • 장민철(KAIST)

  • 박지호(KAIST)

  Inhalable mRNA Nanoparticle with Enhanced Nebulization Stability and Pulmonary Microenvironment Infiltration

  • ACS Nano Aug 22 2024, | https://doi.org/10.1021/acsnano.4c05653

  • 2024.08
  • 바이오·의료융합

• • 한정필(서울대학교)

  • 남유리(KAIST)

  • 이해신(KAIST)

  • 염수청(서울대학교)

  Polyphenol-Enabled 2D Nanopatch for Enhanced Nasal Mucoadhesion and Immune Activation

  • Nano Lett. Aug 09 2024, | https://doi.org/10.1021/acs.nanolett.4c03228

  • 2024.08
  • 바이오·의료융합

• • 이환규(단국대학교)

  Hydrodynamics and Aggregation of Nanoparticles with Protein Corona: Effects of Protein Concentration and Ionic Strength

  • Small Jul 31 2024, | https://doi.org/10.1002/smll.202403913

  • 2024.07
  • 바이오·의료융합

• • Thoa Thi Kim Nguyen(성균관대학교)

  • 우선민(계명대학교 의과대학)

  • 권택규(계명대학교 의과대학)

  • 육심명(성균관대학교)

  Enhanced anticancer efficacy of TRAIL-conjugated and odanacatib-loaded PLGA nanoparticles in TRAIL resistant cancer

  • Biomaterials Jul 30 2024, 312 S0142-9612(24)00267-9 | https://doi.org/10.1016/j.biomaterials.2024.122733

  • 2024.07
  • 의약학

• • 신호정(서울대학교)

  • 민달희(서울대학교)

  A Single-Dose mRNA Vaccine Employing Porous Silica Nanoparticles Induces Robust Immune Responses Against the Zika Virus

  • Adv. Sci. Jul 15 2024, | https://doi.org/10.1002/advs.202404590

  • 2024.07
  • 바이오·의료융합

• • 김서영(한국과학기술연구원)

  • 김성찬(한국과학기술연구원)

  • 김현경(고려대학교 의과대학)

  • 이효진(한국과학기술연구원)

  Improvement of Therapeutic Effect via Inducing Non-Apoptotic Cell Death Using mRNA-Protection Nanocage

  • Adv. Healthc. Mater. Jul 31 2024, | https://doi.org/10.1002/adhm.202400240

  • 2024.07
  • 바이오·의료융합

• • 나기수(POSTECH)

  • 양주성(에스티팜)

  • 김경진(에스티팜)

  • 김동표(POSTECH)

  Full-cycle study on developing a novel structured micromixer and evaluating the nanoparticle products as mRNA delivery carriers

  • J. Control. Release Jul 13 2024, 373 S0168-3659(24)00450-4 | https://doi.org/10.1016/j.jconrel.2024.07.019

  • 2024.07
  • 바이오·의료융합

• • 조하나(가톨릭대학교)

  • 허강무(충남대학교)

  • 강한창(가톨릭대학교 약학대학)

  Selective delivery of imaging probes and therapeutics to the endoplasmic reticulum or Golgi apparatus: Current strategies and beyond

  • Adv. Drug Deliv. Rev. Jul 04 2024, S0169-409X(24)00208-4 | https://doi.org/10.1016/j.addr.2024.115386

  • 2024.07
  • 의약학

• • 진시우(DGIST)

    Interview

  • 이원희(DGIST)

  • 서대하(DGIST)

  Temporal Patterns of Angular Displacement of Endosomes: Insights into Motor Protein Exchange Dynamics

  • Adv. Sci. 2024 Jun 3:e2306849 | https://doi.org/10.1002/advs.202306849

  • 2024.06
  • 바이오·의료융합

• • Divya Shastri(중앙대학교)

  • Vinit Raj(중앙대학교)

  • 이상길(중앙대학교 약학대학)

  Revolutionizing Alzheimer‘s Treatment: Harnessing Human Serum Albumin for Targeted Drug Delivery and Therapy Advancements

  • Ageing Res. Rev. Jun 18 2024, S1568-1637(24)00197-1 | https://doi.org/10.1016/j.arr.2024.102379

  • 2024.06
• 

  임산해

  KAIST

  본 논문은 유전자 교정 도구인 CRISPR/Cas9 system의 ribonucleoprotein (RNP)를 lipid nanoparticle (LNP)에 탑재하여 효과적인 세포 및 암 조직으로의 전달에 대한 연구입니다. CRISPR/Cas9을 전달하는 형태에는 크게 plasmid, mRNA, RNP 3가지로 나눠질 수 있는데, 이중 RNP가 off-target effect가 가장 적어 실제 유전자 치료에 적합한 형태입니다.

  • J. Nanobiotechnol.
  • 2024.06.12

• • Yan Li(Beijing University of Chemical Technology and KAIST)

  • 이상엽(KAIST)

  Engineered polymer nanoparticles as artificial chaperones facilitating the selective refolding of denatured enzymes

  • Proc. Natl. Acad. Sci. USA May 07 2024, 121 (19) | https://doi.org/10.1073/pnas.2403049121

  • 2024.05
  • 생명과학

• • 이예지(이화여자대학교 약학대학)

    Interview

  • 이혁진(이화여자대학교 약학대학)

  Development of Lipid Nanoparticle Formulation for the Repeated Administration of mRNA Therapeutics

  • Biomater. Res. 2024 May 22:28:0017 | https://doi.org/10.34133/bmr.0017

  • 2024.05
  • 바이오·의료융합

• • 김기정(고려대학교)

    Interview

  • 서민규(고려대학교)

  • 천홍구(고려대학교)

  Large-Area Silicon Nitride Nanosieve for Enhanced Diffusion-Based Exosome Isolation

  • Small Methods May 27 2024, | https://doi.org/10.1002/smtd.202301624

  • 2024.05
  • 바이오·의료융합