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'Molecular machine' 에 대한 통합검색결과 66건입니다.

한빛사66건

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- 박영준(University of Washington)
Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses
- Cell February 07, 2025 | https://doi.org/10.1016/j.cell.2024.12.032
- 2025.02
Genome-wide transcriptome analysis of Aβ deposition on PET in a Korean cohort
- Alzheimers. Dement. 08 November 2024 | https://doi.org/10.1002/alz.14348
- 2024.11
- 생명과학
- 이소현(ETH Zurich, 현 KAIST 생명과학과)
High-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activity
- Nat. Med. Sep 20 2024, | https://doi.org/10.1038/s41591-024-03224-y
- 2024.09
- 이권무(Boston Children's Hospital, Harvard Medical School)
Interpretable Fine-Grained Phenotypes of Subcellular Dynamics via Unsupervised Deep Learning
- Adv. Sci. 06 September 2024 | https://doi.org/10.1002/advs.202403547
- 2024.09
- 바이오·의료융합
Systematic Selection of High-Affinity ssDNA Sequences to Carbon Nanotubes
- Adv. Sci. 25 June 2024 | https://doi.org/10.1002/advs.202308915
- 2024.06
- 바이오·의료융합
명유찬

The University of Queensland

최근 신약 개발 동향을 살펴보면, 대형 제약회사의 전임상 연구 중 Pharmacokinetics (PK) 와 독성 평가단계에서 가장 많은 약물 후보물질들이 리스트에서 제외된다고 합니다. 결국, 후보물질 스크리닝 단계에서 물질의 효능만을 살펴보는 것이 아니라 PK 및 독성 예측값을 사용하여 후보 물질의 개발성 (developability)을 전반적으로 평가하는 것이 신약 개발 성공률을 높이는 방법이 될 것입니다.
- Nucleic Acids Res.
- 2024.05.07
Time-resolved profiling of RNA binding proteins throughout the mRNA life cycle
- Mol. Cell April 08, 2024 | https://doi.org/10.1016/j.molcel.2024.03.012
- 2024.04
- 생명과학
- Surendra Kumar(가천대학교)
- 김미현(가천대학교)
GPCR-IPL score: multilevel featurization of GPCR-ligand interaction patterns and prediction of ligand functions from selectivity to biased activation
- Brief. Bioinform. Volume 25, Issue 2, March 2024, bbae105 | https://doi.org/10.1093/bib/bbae105
- 2024.03
- 문태석(Washington University in St. Louis)
Advances in ligand-specific biosensing for structurally similar molecules
- Cell Syst. Dec 20 2023, 14 (12) S2405-4712(23)00301-0 | https://doi.org/10.1016/j.cels.2023.10.009
- 2023.12
- 생명과학
- 김민재(The University of Tennessee Health Science Center)
Computational methods in glaucoma research: Current status and future outlook
- Mol. Asp. Med. Nov 03 2023, 94 S0098-2997(23)00062-6 | https://doi.org/10.1016/j.mam.2023.101222
- 2023.11
- 남도현(성균관대학교 의과대학, 삼성의료원)
Identifying predictors of glioma evolution from longitudinal sequencing.
- Sci. Transl. Med. Oct 04 2023, 15 (716) | https://doi.org/10.1126/scitranslmed.adh4181
- 2023.10
- 의약학
Glutathione dynamics is a potential predictive and therapeutic trait for neoadjuvant chemotherapy response in bladder cancer
- Cell Rep. Med. October 04, 2023 | https://doi.org/10.1016/j.xcrm.2023.101224
- 2023.10
- 의약학
- 양애린(Stanford University)
Deploying synthetic coevolution and machine learning to engineer protein-protein interactions
- Science 2023 Jul 28;381(6656):eadh1720 | DOI: 10.1126/science.adh1720
- 2023.07
- 생명과학
- 이수인(University of Washington)
Uncovering expression signatures of synergistic drug responses via ensembles of explainable machine-learning models
- Nat. Biomed. Eng. Published: 01 May 2023 | https://doi.org/10.1038/s41551-023-01034-0
- 2023.05
- 이정연(Delaware Biotechnology Institute, University of Delaware)
Targeting of plasmodesmal proteins requires unconventional signals
- Plant Cell 2023 May 24;koad152 | https://doi.org/10.1093/plcell/koad152
- 2023.05
- 윤정열(The University of Arizona)
Receptor-based detection of microplastics and nanoplastics: Current and future
- Biosens. Bioelectron. Available online 28 April 2023 | https://doi.org/10.1016/j.bios.2023.115361
- 2023.04
Karolina Pra?anowska

아주대학교 의과대학

In our paper titled "An Integrated Single-Cell Transcriptomic Dataset for Non-Small Cell Lung Cancer," we present a comprehensive dataset of single-cell RNA sequencing (scRNA-seq) data from human primary non-small cell lung cancer tumors. As the trend of precision medicine continues, scRNA-seq has been widely used to study cellular heterogeneity in tumors over the past decade.
- Sci. Data
- 2023.04.10
Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma
- Genome Med. 2023 Mar 13;15(1):16 | https://doi.org/10.1186/s13073-023-01165-8
- 2023.03
- 의약학
- 아나미카 쿠쉬와하(충북대학교)
- 김범수(충북대학교)
Biodegradation of poly(ethylene terephthalate): Mechanistic insights, advances, and future innovative strategies
- Chem. Eng. J. Volume 457, 1 Feb 2023, 141230 | http://doi.org/10.1016/j.cej.2022.141230
- 2023.02
- 생명과학
- Liang Shi(고려대학교, Nanjing Agricultural University)
- 옥용식(고려대학교)
Modeling phytoremediation of heavy metal contaminated soils through machine learning
- J. Hazard. Mater. Vol 441, 5 Jan 2023, 129904 | https://doi.org/10.1016/j.jhazmat.2022.129904
- 2023.01
- 바이오·의료융합