통합검색
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'Medicinal Chemistry' 에 대한 통합검색결과 71건입니다.
한빛사71건
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A Three-In-One Heptamethine Cyanine Dye Induces Endoplasmic Reticulum Stress and Apoptosis in Colorectal Cancer
- Adv. Healthc. Mater. Dec 25 2024, | https://doi.org/10.1002/adhm.202404027
- 2024.12
- 바이오·의료융합
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Glycosidase-targeting small molecules for biological and therapeutic applications.
- Chem. Soc. Rev. Sep 06 2023 | https://doi.org/10.1039/d3cs00032j
- 2023.09
- 바이오·의료융합
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An optimized Nurr1 agonist provides disease-modifying effects in Parkinson’s disease models
- Nat. Commun. 18 July 2023 | https://doi.org/10.1038/s41467-023-39970-9
- 2023.07
- 생명과학
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Photon-Controlled Pyroptosis Activation (PhotoPyro): An Emerging Trigger for Antitumor Immune Response
- J. Am. Chem. Soc. 2023 Mar 22;145(11):6007-602 | https://doi.org/10.1021/jacs.3c01231
- 2023.03
- 의약학
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Targeted Degradation of PRC1 Components, BMI1 and RING1B, via a Novel Protein Complex Degrader Strategy
- Adv. Sci. First published: 03 February 2023 | https://doi.org/10.1002/advs.202205573
- 2023.02
- 의약학
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Nano drug delivery systems for antisense oligonucleotides (ASO) therapeutics
- J. Control. Release 2022 Dec;352:861-878 | https://doi.org/10.1016/j.jconrel.2022.10.050
- 2022.12
- 바이오·의료융합
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Multifunctional Photo-Cross-Linking Probes: From Target Protein Searching to Imaging Applications
- Acc. Chem. Res. Publication Date:December 19, 2022 | https://doi.org/10.1021/acs.accounts.2c00505
- 2022.12
- 생명과학
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Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy
- Chem. Soc. Rev. 2022 Oct 31;51(21):8957-9008 | https://doi.org/10.1039/D2CS00722C
- 2022.10
- 바이오·의료융합
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Macrocyclization and Backbone Modification in RiPP Biosynthesis
- Annu. Rev. Biochem. Review in Advance first posted online on March 18, 2022 | https://doi.org/10.1146/annurev-biochem-032620-104956
- 2022.03
- 의약학
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Pnictogens in medicinal chemistry: evolution from erstwhile drugs to emerging layered photonic nanomedicine
- Chem. Soc. Rev. First published 24 Dec 2020 | https://doi.org/10.1039/D0CS01175D
- 2020.12
- 바이오·의료융합
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[Perspective]Targeting KRAS(G12C): From Inhibitory Mechanism to Modulation of Antitumor Effects in Patients
- Cell Published:October 15, 2020 | https://doi.org/10.1016/j.cell.2020.09.044
- 2020.10
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Anti-inflammatory effect of a novel synthetic compound 1-((4-fluorophenyl)thio)isoquinoline in RAW264.7 macrophages and a zebrafish model
- Fish Shellfish Immunol. Available online 25 January 2019, Volume 87, Pages 395-400 | https://doi.org/10.1016/j.fsi.2019.01.030
- 2019.01
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Licoflavonol Reduces Aβ Secretion by Increasing BACE1 Phosphorylation to Facilitate BACE1 Degradation
- Mol. Nutr. Food Res. First published: 26 October 2018 | https://doi.org/10.1002/mnfr.201800474
- 2018.10
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Mechanistic applications of click chemistry for pharmaceutical drug discovery and drug delivery
- Drug Discov. Today Volume 22, Issue 11, November 2017, Pages 1604-1619, https://doi.org/10.1016/j.drudis.2017.07.007
- 2017.11
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Two-Photon Dye Cocktail for Dual-Color 3D Imaging of Pancreatic Beta and Alpha Cells in Live Islets
- J. Am. Chem. Soc. Publication Date (Web): February 6, 2017 | DOI: 10.1021/jacs.6b12122
- 2017.02
- 바이오·의료융합
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Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader–Willi syndrome
- Nat. Med. Published online 26 December | doi:10.1038/nm.4257
- 2016.12
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Interferon lambda 4 expression is suppressed by the host during viral infection
- J. Exp. Med. Published October 31, 2016 | DOI: 10.1084/jem.20160437
- 2016.10
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Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer’s disease
- Nat. Commun. Published online:13 October 2016 | doi:10.1038/ncomms13115
- 2016.10
- 생명과학
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A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters
- J. Am. Chem. Soc. Publication Date (Web): September 19, 2016 | DOI: 10.1021/jacs.6b07598
- 2016.09
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Infection-specific phosphorylation of glutamyl-prolyl tRNA synthetase induces antiviral immunity
- Nat. Immunol. Published online 05 September 2016 | doi:10.1038/ni.3542
- 2016.09
- 생명과학
