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1Leukemia

'Leukemia' 에 대한 통합검색결과 312건입니다.

한빛사312건

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Increased local DNA methylation disorder in AMLs with DNMT3A-destabilizing variants and its clinical implication
- Nat. Commun. Jan 10 2025, 16 (1) 560 | https://doi.org/10.1038/s41467-024-55691-z
- 2025.01
- 의약학
- 정윤주(Brigham & Women's Hospital, Harvard Medical School, (현) 경희대학교)
  Interview
Leukemia inhibitory factor (LIF) receptor amplifies pathogenic activation of fibroblasts in lung fibrosis
- Proc. Natl. Acad. Sci. USA Dec 10 2024, 121 (50) | https://doi.org/10.1073/pnas.2401899121
- 2024.12
- 의약학
정윤주

Brigham & Women's Hospital, Harvard Medical School, (현) 경희대학교

특발성 폐 섬유증은 알 수 없는 원인으로 폐가 서서히 굳어가며 사망에 이르는 법으로, 현재 승인된 표적 치료제가 없이 증상의 진행을 늦추는 약 또는 이식 수술만 가능한 질병입니다. 폐 섬유증은 질병 환경에서 활성화된 섬유아세포(fibroblast)에서 콜라겐 등 세포외 기질이 과다하게 분비되어 주변 조직을 딱딱하게 만들며 진행되지만, 왜 이런 현상이 일어나는지에 대한 작용 기전이 완전히 밝혀져있지 않습니다.
- Proc. Natl. Acad. Sci. USA
- 2024.12.17
- 정효빈(연세대학교)
Single-cell multiomics analysis reveals dynamic clonal evolution and targetable phenotypes in acute myeloid leukemia with complex karyotype
- Nat. Genet. 25 November 2024 | https://doi.org/10.1038/s41588-024-01999-x
- 2024.11
- 류아람(University of California San Francisco)
Cells and signals of the leukemic microenvironment that support progression of T-cell acute lymphoblastic leukemia (T-ALL)
- Exp. Mol. Med. Nov 01 2024, | https://doi.org/10.1038/s12276-024-01335-7
- 2024.11
- 생명과학
The impact of atmospheric ultrafine particulate matter on IgE-mediated type 1 hypersensitivity reaction
- J. Hazard. Mater. Nov 29 2024, 484 S0304-3894(24)03286-2 | https://doi.org/10.1016/j.jhazmat.2024.136705
- 2024.11
- 생명과학
The inflammasome-activating poxvirus peptide IAMP29 promotes antimicrobial and anticancer responses
- Exp. Mol. Med. Nov 01 2024, | https://doi.org/10.1038/s12276-024-01339-3
- 2024.11
- 의약학
CD13-targeting and TRAIL-displaying protein nanoparticles effectively induce apoptotic cell death of acute myeloid leukemia, prolonging survival in mo
- Nano Today Available online 4 September 2024 | https://doi.org/10.1016/j.nantod.2024.102474
- 2024.09
- 생명과학
Polyubiquitinated PCNA triggers SLX4-mediated break-induced replication in alternative lengthening of telomeres (ALT) cancer cells
- Nucleic Acids Res. Sep 18 2024, gkae785 | https://doi.org/10.1093/nar/gkae785
- 2024.09
- 생명과학
- 이평세(Harvard Medical School / UC Berkeley)
Acoustofluidic Virus Isolation via Bessel Beam Excitation Separation Technology
- ACS Nano Aug 12 2024, | https://doi.org/10.1021/acsnano.4c09692
- 2024.08
- 바이오·의료융합
REXO5 promotes genomic integrity through regulating R-loop using its exonuclease activity
- Leukemia Published: 30 July 2024 | https://doi.org/10.1038/s41375-024-02362-z
- 2024.07
- 바이오·의료융합
- 이재웅(고려대학교, Yale School of Medicine)
Leveraging altered lipid metabolism in treating B cell malignancies
- Progr Lipid Res Volume 95, July 2024, 101288 | https://doi.org/10.1016/j.plipres.2024.101288
- 2024.07
- 생명과학
- 최진혁(University of Texas Southwestern Medical Center)
Disruption of the ZFP574?THAP12 complex suppresses B cell malignancies in mice
- Proc. Natl. Acad. Sci. USA July 24, 2024 | https://doi.org/10.1073/pnas.2409232121
- 2024.07
- 정양조(NIH)
The DNA methyltransferase inhibitor 5-aza-4‘-thio-2‘-deoxycytidine induces C>G transversions and acute lymphoid leukemia development
- Cancer Res. 2024 Jun 4 | https://doi.org/10.1158/0008-5472.CAN-23-2785
- 2024.06
Automation of 3D digital rolling circle amplification using a 3D-printed liquid handler
- Biosens. Bioelectron. Available online 16 June 2024 | https://doi.org/10.1016/j.bios.2024.116503
- 2024.06
- 바이오·의료융합
- 권민철(Janssen R&D)
Preclinical efficacy of potent and selective menin-KMT2A inhibitor JNJ-75276617 in KMT2A- and NPM1-altered leukemias
- Blood Jun 21 2024, blood.2023022480 | https://doi.org/10.1182/blood.2023022480
- 2024.06
- 최진혁(University of Texas Southwestern Medical Center)
Viable mutations of mouse midnolin suppress B cell malignancies
- J. Exp. Med. April 16 2024 | https://doi.org/10.1084/jem.20232132
- 2024.04
- 이재은(서울대학교)
  Interview
- 이현숙(서울대학교)
Disruption of G-quadruplex dynamicity by BRCA2 abrogation instigates phase separation and break-induced replication at telomeres
- Nucleic Acids Res. Apr 08 2024, gkae251 | https://doi.org/10.1093/nar/gkae251
- 2024.04
- 생명과학
- James J. Moon(University of Michigan)
STING-activating cyclic dinucleotide-manganese nanoparticles evoke robust immunity against acute myeloid leukemia
- J. Control. Release Mar 14 2024, S0168-3659(24)00174-3 | https://doi.org/10.1016/j.jconrel.2024.03.022
- 2024.03
Impaired binding affinity of YTHDC1 with METTL3/METTL14 results in R-loop accumulation in myelodysplastic neoplasms with DDX41 mutation
- Leukemia Mar 21 2024, | https://doi.org/10.1038/s41375-024-02228-4
- 2024.03
- 의약학