한빛사182건

• • 박나은(가톨릭대학교)

  • 김경섭(가톨릭대학교)

  • 나건(가톨릭대학교)

  Adipose-derived stem cell-based anti-inflammatory paracrine factor regulation for the treatment of inflammatory bowel disease

  • J. Control. Release Aug 23 2024, 374 S0168-3659(24)00574-1 | https://doi.org/10.1016/j.jconrel.2024.08.027

  • 2024.08
  • 바이오·의료융합

• • 김정욱(서울대학교)

  • 안영현(서울대학교)

  • 황석연(서울대학교)

  Electrical Stimulating Redox Membrane Incorporated with PVA/Gelatin Nanofiber for Diabetic Wound Healing

  • Adv. Healthc. Mater. Jul 11 2024, | https://doi.org/10.1002/adhm.202400170

  • 2024.07
  • 바이오·의료융합
• 

  나현지

  고려대학교

  Black phosphorus quantum dots (BPQDs)는 생체 적합성이 높고, 우수한 광열 전환율(photo thermal conversion)을 가지고 있어 바이오이미징 및 암 치료에 활발하게 사용되고 있습니다. 특히, 위 논문과 같이 광열 치료(Photothermal Therapy, PTT)에서 암세포만을 선택적으로 파괴하는 데 효과적입니다.

  • Biomaterials
  • 2024.07.18

• • 정영록(Tessa Therapeutic)

  Overexpression of an Engineered SerpinB9 Enhances Allogeneic T-Cell Persistence and Efficacy

  • Cancer Immunol. Res. 2024 Jun 4 | https://doi.org/10.1158/2326-6066.CIR-23-1001

  • 2024.06

• • 정혜우(한양대학교)

  • 변하연(한양대학교)

  • 이진규(한양대학교)

  • 신흥수(한양대학교)

  Enhancement of Bone Tissue Regeneration with Multi-Functional Nanoparticles by Coordination of Immune, Osteogenic, and Angiogenic Responses

  • Adv. Healthc. Mater. May 02 2024, | https://doi.org/10.1002/adhm.202400232

  • 2024.05
  • 생명과학

• • 박지은(고려대학교)

  • 김동휘(고려대학교)

  Advanced Immunomodulatory Biomaterials for Therapeutic Applications

  • Adv. Healthc. Mater. May 08 2024, | https://doi.org/10.1002/adhm.202304496

  • 2024.05
  • 생명과학

• • 강희민(고려대학교)

  Multimodal biomedical utility of polyaniline-based supramolecular nanomaterials

  • Chem. Eng. J. Available online 24 May 2024 | https://doi.org/10.1016/j.cej.2024.15253

  • 2024.05
  • 바이오·의료융합

• • 조영석(University of Michigan)

  • James J. Moon(University of Michigan)

  Novel strategies for modulating the gut microbiome for cancer therapy

  • Adv. Drug Deliv. Rev. May 15 2024, 210 S0169-409X(24)00154-6 | https://doi.org/10.1016/j.addr.2024.115332

  • 2024.05
  • 의약학

• • James J. Moon(University of Michigan)

  Self-Assembled STING-Activating Coordination Nanoparticles for Cancer Immunotherapy and Vaccine Applications

  • ACS Nano Apr 16 2024, 18 (15) | https://doi.org/10.1021/acsnano.3c11374

  • 2024.04

• • 김성웅(Cornell University)

  Functionalized nanowires for miRNA-mediated therapeutic programming of na?ve T cells

  • Nat. Nanotechnol. 29 April 2024 | https://doi.org/10.1038/s41565-024-01649-7

  • 2024.04
  • 생명과학
• 

  이대용

  University of Texas MD Anderson Cancer Center

  세포 내 DNA 센서는 이중 가닥 DNA나 순환 뉴클레오타이드와 같은 천연 작용제에 의해 활성화되어 항원 제시 세포(APCs)에서 선천 면역을 조절하고 후천 면역 반응을 유도할 수 있습니다. 그러나 세포 내 전달, 혈청 안정성, 효소적 분해 등의 문제로 인해 이러한 센서의 활성화는 어려움을 겪고 있습니다. 본 연구에서는 나선 모양 폴리펩타이드의 특성이 APCs에서 천연 면역 경로를 자극할 수 있다는 것이 밝혔습니다.

  • Nat. Biomed. Eng.
  • 2024.04.24

• • 최다희(연세대학교, 현 Mayo Clinic)

  • 강태건(연세대학교, 현 St Jude Children's Research Hospital)

  • 김태현(연세대학교)

  • 문채원(연세대학교)

  • 홍진기(연세대학교)

  • 하상준(연세대학교)

  Immortalized nanodendritic cells decorated with immune-checkpoint inhibitors for personalized cancer immunotherapy

  • Nano Today Available online 27 March 2024 | https://doi.org/10.1016/j.nantod.2024.102237

  • 2024.03
  • 생명과학

• • 하현수(연세대학교 의과대학)

  • 백세움(연세대학교 의과대학)

  • 이규배(연세대학교 의과대학, 건양대학교)

  • 강상욱(연세대학교 의과대학)

  • 성학준(연세대학교 의과대학)

  Artificial Vasa-Vasorum Serves as an On-Site Regenerative Promoter of Cell-Free Vascular Grafting

  • Adv. Funct. Mater. 10 March 2024 | https://doi.org/10.1002/adfm.202315310

  • 2024.03
  • 바이오·의료융합

• • 박상우(Cornell University, 현 Harvard Medical School / Massachusetts General Hospital)

    Interview

  Immunoengineering can overcome the glycocalyx armour of cancer cells

  • Nat. Mater. Published: 15 February 2024 | https://doi.org/10.1038/s41563-024-01808-0

  • 2024.02
  • 생명과학

• • Amal George Kurian(단국대학교)

  • 김해원(단국대학교 조직재생공학연구원/치과대학)

  Nanozyme-Engineered Hydrogels for Anti-Inflammation and Skin Regeneration

  • Nano-Micro Lett. Feb 06 2024, 16 (1) 110 | https://doi.org/10.1007/s40820-024-01323-6

  • 2024.02
  • 의약학
• 

  최재혁

  Northwestern University

  Adoptive T cell therapies have produced spectacular results in multiple treatment-related diseases. However, they have failed to make a significant impact on solid tumors, which represent >90% of all adult cancers. Solid tumors have an immunosuppressive microenvironment that limits T cell persistence and potency. To overcome this barrier and address the important clinical unmet need, we turned to extranodal T cell lymphomas, which develop mutations that increase T cell fitness in analogous microenvironments.

  • Nature
  • 2024.02.20
• 

  이효형

  서울대학교, Icahn School of Medicine at Mount Sinai

  Psoriasis is a chronic, T-cell-mediated inflammatory skin disease with a Th17-skewed immune phenotype. Regulatory T cells (Tregs) play a key role in suppressing the inflammatory immune response and inducing immune homeostasis and self-tolerance. While the role of Tregs in the pathogenesis of psoriasis has been proposed, the exact mechanisms of action and the molecular characterization of skin-homing psoriatic Tregs has not yet been well explored.

  • EBioMedicine
  • 2024.02.16

• • 김성준(동국대학교)

    Interview

  • Shujin Li(연세대학교)

  • 정한성(연세대학교)

  • 김교범(동국대학교)

  Surface Engineering of Natural Killer Cells with CD44-targeting Ligands for Augmented Cancer Immunotherapy

  • Small Dec 31 2023, | https://doi.org/10.1002/smll.202306738

  • 2023.12
  • 생명과학

• • 김재현(한양대학교)

    Interview

  • 김용희(한양대학교)

  Engineering TGF-β inhibitor-encapsulated macrophage-inspired multi-functional nanoparticles for combination cancer immunotherapy

  • Biomater. Res. Dec 18 2023, 27 (1) | https://doi.org/10.1186/s40824-023-00470-y

  • 2023.12
  • 생명과학

• • 박성국(울산과학기술원)

  • 김효정(울산과학기술원)

  • 박성호(울산과학기술원)

  • 강세병(울산과학기술원)

  Protein cage nanoparticle-based NK cell-engaging nanodrones (NKeNDs) effectively recruit NK cells to target tumor sites and suppress tumor growth

  • Nano Today Available online 2 December 2023 | https://doi.org/10.1016/j.nantod.2023.102075

  • 2023.12
  • 생명과학