High-throughput screening > 통합검색

통합검색

한빛사

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1High-throughput screening

'High-throughput screening' 에 대한 통합검색결과 170건입니다.

한빛사170건

최신순
관련도순

Kojo Eghan

안전성평가연구소

Our study focuses on evaluating the neurotoxic effects of 2-ethylhexanol, a chemical widely used in industrial applications, including plastic production, solvents, and fragrances. Despite its widespread presence in the environment, its potential impact on neurodevelopment has not been fully explored.
- J. Hazard. Mater.
- 2025.02.11
- 홍서정(Columbia University Vagelos College of Physicians and Surgeons)
A multiplex method for rapidly identifying viral protease inhibitors
- Mol. Syst. Biol. Jan 06 2025, | https://doi.org/10.1038/s44320-024-00082-1
- 2025.01
Cell-free systems: A synthetic biology tool for rapid prototyping in metabolic engineering
- Biotechnol. Adv. Available online 23 January 2025, 108522 | https://doi.org/10.1016/j.biotechadv.2025.108522
- 2025.01
- 생명과학
이정호

Ghent University

Bio-based long-chain dicarboxylic acids (LCDAs) are in high demand in the polymer industry. These compounds have diverse applications as building blocks for polymers with distinct features, which lead to a fast-growing global LCDA market. However, bio-based LCDA production is currently limited in Europe as established processes are using the pathogenic yeast, Candida tropicalis.
- Bioresour. Technol.
- 2025.01.14
Highly Stretchable 3D Microelectrode Array for Noninvasive Functional Evaluation of Cardiac Spheroids and Midbrain Organoids
- Adv. Mater. Dec 15 2024, | https://doi.org/10.1002/adma.202412953
- 2024.12
- 바이오·의료융합
Liver organoids: Current advances and future applications for hepatology
- Clin. Mol. Hepatol. Dec 26 2024, | https://doi.org/10.3350/cmh.2024.1040
- 2024.12
- 의약학
Clinically-Driven Rapidly Developed Nanoparticle Corona for Label-Free Cerebrospinal Fluid Leakage Detection
- ACS Nano Dec 23 2024, | https://doi.org/10.1021/acsnano.4c12364
- 2024.12
- 바이오·의료융합
Saturation profiling of drug-resistant genetic variants using prime editing
- Nat. Biotechnol. 12 November 2024 | https://doi.org/10.1038/s41587-024-02465-z
- 2024.11
- 생명과학
- 이은영(연세대학교)
- 신용(연세대학교)
Programmable DNA-based nanostructure sensors for mutation detection coupled with asymmetric amplification in precision genome profiling
- Chem. Eng. J. Volume 500, 15 November 2024, 157436 | https://doi.org/10.1016/j.cej.2024.157436
- 2024.11
- 바이오·의료융합
오형철

연세대학교 의과대학

시퀀싱 기술의 발전으로 인해 암을 비롯한 다양한 질환에서 수많은 돌연변이가 발견되었고, 이 중 일부는 병리학적(Pathologic) 또는 양성(Benign)으로 밝혀졌지만, 대부분의 돌연변이는 여전히 의미를 알 수 없는 변이(Variants of Uncertain Significance, VUS)로 남아 있습니다. 이러한 VUS의 기능을 밝히기 위해 전 세계의 많은 연구팀이 심혈을 기울이고 있으며, 이를 통해 환자의 치료 방향을 제시하거나 예후를 예측하려는 노력을 기울이고 있습니다.
- Nat. Biotechnol.
- 2024.11.18
- 이소현(ETH Zurich, 현 KAIST 생명과학과)
High-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activity
- Nat. Med. Sep 20 2024, | https://doi.org/10.1038/s41591-024-03224-y
- 2024.09
- 윤솔지(연세대학교)
  Interview
- 김영수(연세대학교 약학과)
Drug Discovery and Screening Tool Development for Tauopathies by Focusing on Pathogenic Tau Repeat 3 Oligomers
- Angew. Chem.-Int. Edit. Sep 24 2024, | https://doi.org/10.1002/anie.202411942
- 2024.09
- 의약학
- 신수련(Harvard Medical School/Brigham and Women’s Hospital)
Brain-on-a-chip: an emerging platform for studying the nanotechnology-biology interface for neurodegenerative disorders
- J. Nanobiotechnol. Sep 18 2024, 22 (1) | https://doi.org/10.1186/s12951-024-02720-0
- 2024.09
- 바이오·의료융합
- 이기범(Rutgers, The State University of New Jersey)
Probing Nanotopography-Mediated Macrophage Polarization via Integrated Machine Learning and Combinatorial Biophysical Cue Mapping
- ACS Nano September 3, 2024 | https://doi.org/10.1021/acsnano.4c04406
- 2024.09
- 바이오·의료융합
이용욱

University of Massachusetts Chan Medical School

현재 밝혀진 많은 물질대사 경로는 수많은 노선이 얽힌 서울의 지하철 노선도처럼 출발점과 도착지를 잇는 여러 선택 가능한 경로가 존재합니다. 저의 연구는 마치 지하철역 하나가 폐쇄되었을 때 이용객들이 어떤 다른 경로를 가장 많이 사용할지 살펴보는 것과 같이, 선천성 대사이상 (inborn errors of metabolism)에 관련된 효소 유전자의 돌연변이로 인해 전체 물질대사가 어떻게 재구성되는가를 살펴보는 것으로 시작되었습니다.
- Nat Metab.
- 2024.09.05
- 한희선(University of Illinois at Urbana-Champaign)
Drop-by-Drop Addition of Reagents to a Double Emulsion
- Small Aug 05 2024, | https://doi.org/10.1002/smll.202404121
- 2024.08
Integrating Vascular Phenotypic and Proteomic Analysis in an Open Microfluidic Platform
- ACS Nano Aug 29 2024, | https://doi.org/10.1021/acsnano.4c05537
- 2024.08
- 바이오·의료융합
- 주철민(Delft University of Technology, 이화여자대학교)
Single-molecule structural and kinetic studies across sequence space
- Science 2024 Aug 23;385(6711):898-904 | https://doi.org/10.1126/science.adn5968
- 2024.08
- 생명과학
- 이하원(St. Jude Children's Research Hospital)
A high-content screen of FDA approved drugs to enhance CAR T cell function: ingenol-3-angelate improves B7-H3-CAR T cell activity by upregulating B7-H
- J. Exp. Clin. Cancer Res. Apr 01 2024, 43 (1) 97 | https://doi.org/10.1186/s13046-024-03022-x
- 2024.04
- 명유찬(The University of Queensland)
  Interview
Deep-PK: deep learning for small molecule pharmacokinetic and toxicity prediction
- Nucleic Acids Res. Apr 18 2024, gkae254 | https://doi.org/10.1093/nar/gkae254
- 2024.04