통합검색

한빛사

내가 찾은 검색어

1Embryo Implantation

'Embryo Implantation' 에 대한 통합검색결과 20건입니다.

한빛사20건

최신순
관련도순

CFP1 governs uterine epigenetic landscapes to intervene in progesterone responses for uterine physiology and suppression of endometriosis
- Nat. Commun. 03 June 2023 | https://doi.org/10.1038/s41467-023-39008-0
- 2023.06
- 김연선(Cincinnati Children’s Hospital Medical Center)
An unanticipated discourse of HB-EGF with VANGL2 signaling during embryo implantation
- Proc. Natl. Acad. Sci. USA 2023 May 16;120(20):e2302937120 | https://doi.org/10.1073/pnas.2302937120
- 2023.05
- 생명과학
Development of cell-laden multimodular Lego-like customizable endometrial tissue assembly for successful tissue regeneration
- Biomater. Res. 2023 Apr 21;27(1):33 | https://doi.org/10.1186/s40824-023-00376-9
- 2023.04
- 의약학
Intrauterine botulinum toxin A administration promotes endometrial regeneration mediated by IGFBP3-dependent OPN proteolytic cleavage in thin endometr
- Cell. Mol. Life Sci. 2023 Jan 5;80(1):26 | https://doi.org/10.1007/s00018-022-04684-6
- 2023.01
- 의약학
Ethalfluralin induces developmental toxicity in zebrafish via oxidative stress and inflammation
- Sci. Total Environ. 2022 Sep 14;854:158780 | https://doi.org/10.1016/j.scitotenv.2022.158780
- 2022.09
- 생명과학
- 성진우(Institute of Molecular Biotechnology, Austrian Academy of Sciences (IMBA))
  Interview
Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero
- Cell Stem Cell Volume 29, Issue 7, 7 July 2022, Pages 1102-1118.e8 | https://doi.org/10.1016/j.stem.2022.06.002
- 2022.07
- 생명과학
- 허동은(University of Pennsylvania)
A microphysiological model of human trophoblast invasion during implantation
- Nat. Commun. Published 15 March 2022 | https://doi.org/10.1038/s41467-022-28663-4
- 2022.03
- 바이오·의료융합
- 김영수(Max Planck Institute for Molecular Biomedicine)
Deciphering epiblast lumenogenesis reveals proamniotic cavity control of embryo growth and patterning
- Sci. Adv. 10 Mar 2021: Vol. 7, no. 11, eabe1640 | DOI: 10.1126/sciadv.abe1640
- 2021.03
- 생명과학
- 홍승희(Weill Cornell Medicine, Baylor Institute for Immunology Research)
Longitudinal profiling of human blood transcriptome in healthy and lupus pregnancy
- J. Exp. Med. Published April 8, 2019 | DOI: 10.1084/jem.20190185
- 2019.04
- 차지연(Vanderbilt University Medical Center)
[Commentary]Hunting for Fox(A2): Dual roles in female fertility
- Proc. Natl. Acad. Sci. USA Published online before print January 25, 2017 | doi: 10.1073/pnas.1620648114
- 2017.01
- 신종대(University of Massachusetts Medical School)
RLIM is dispensable for X-chromosome inactivation in the mouse embryonic epiblast
- Nature Published online 25 May 2014 | doi:10.1038/nature13286
- 2014.05
- 차지연(University of Cincinnati College of Medicine)
  Interview
Conditional Deletion of MSX Homeobox Genes in the Uterus Inhibits Blastocyst Implantation by Altering Uterine Receptivity
- Dev. Cell 17 November 2011 | 10.1016/j.devcel.2011.09.010
- 2011.11
차지연

University of Cincinnati College of Medicine

1. You recently published a paper, in the journal "Dev. Cell, 17 November 2011 | 10.1016/j.devcel.2011.09.010", titled "Conditional Deletion of MSX Homeobox Genes in the Uterus Inhibits Blastocyst Implantation by Altering Uterine Receptivity". - Can you please briefly summarize this paper? This manuscript outlines a critical role for Msx homeobox genes, known to be required for fetal development of multiple organ systems, in female fertility during embryo implantation. Implantation is the first intimate and bidirectional communication between an implantation-competent blastocyst and the receptive uterus. The blastocyst will implant only when this molecular cross-talk is established. By using several genetically engineered mouse models, we found that gene-deleted mice exhibited graded levels of compromised fertility depending on a single or double deletion of Msx genes in the uterus. Mice singly deleted of Msx1 produced either smaller than normal litter sizes or no litters at all, while deletion of both Msx1 and Msx2 genes resulted in complete infertility due to implantation failure. However, this infertility was not due to defective ovulation, fertilization or preimplantation embryo development. To explain compromised implantation, we found that loss of uterine Msx1/Msx2 expression correlates with altered uterine luminal epithelial cell polarity and degree of E-cadherin/β-catenin complex formation through regulation of Wnt5a expression. Application of Wnt5a in vitro compromised blastocyst invasion and trophoblast outgrowth on cultured uterine epithelial cells but not in the absence of epithelial cells. Our finding that Msx1/Msx2 genes are critical for conferring uterine receptivity and readiness to implantation could have clinical significance, because compromised uterine receptivity is a major cause of pregnancy failure in in vitro fertilization-embryo transfer (IVF-ET) programs, which have a low success rate of 30%. Furthermore, gene analysis has shown that
- Dev. Cell
- 2011.11.28
- 이유성(Baylor College of Medicine)
Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus
- Nat. Genet. Published online: 3 September 2006
- 2006.09
- 정영기(Advanced Cell Technology, Worcester)
Embryonic and extraembryonic stem cell lines derived from single mouse blastomeres
- Nature published online 16 October 2005
- 2005.10
- 정영기(Advanced Cell Technology, Worcester)
Embryonic and extraembryonic stem cell lines derived from single mouse blastomeres
- Nature published online 16 October 2005
- 2005.10
- 김진문(University of Tokyo)
Regulation of histone H3 lysine 9 methylation in oocytes and early pre-implantation embryos
- Development 131, 2269-2280 (2004)
- 2004.05
- 강용국(한국생명공학연구원, Harvard Medical School)
Histone H3-K9 Methyltransferase ESET Is Essential for Early Development
- Mol. Cell. Biol. March 2004 vol. 24 no. 6 2478-2486 | doi: 10.1128/MCB.24.6.2478-2486.2004
- 2004.03
- 임현정(University of Kansas Medical Center, 현재 건국대학교)
Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARδ
- Genes Dev. 1999. 13: 1561-1574
- 1999.06
- 의약학
- 임현정(University of Kansas Medical Center, 현재 건국대학교)
Hoxa-10 Regulates Uterine Stromal Cell Responsiveness to Progesterone during Implantation and Decidualization in the Mouse
- Mol. Endocrinol. 13 (6): 1005-1017.
- 1999.06
- 의약학