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'Drug Discovery' 에 대한 통합검색결과 311건입니다.
한빛사311건
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New insights into protein-protein interaction modulators in drug discovery and therapeutic advance
- Signal Transduct. Target. Ther. Dec 06 2024, 9 (1) 341 | https://doi.org/10.1038/s41392-024-02036-3
- 2024.12
- 의약학
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Chemical-Driven Amyloid Clearance for Therapeutics and Diagnostics of Alzheimer‘s Disease
- Acc. Chem. Res. Nov 04 2024, | https://doi.org/10.1021/acs.accounts.4c00458
- 2024.11
- 의약학
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Integrative pathway analysis across humans and 3D cellular models identifies the p38 MAPK-MK2 axis as a therapeutic target for Alzheimer’s disease
- Neuron November 27, 2024 | https://doi.org/10.1016/j.neuron.2024.10.029
- 2024.11
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Single-cell multiomics analysis reveals dynamic clonal evolution and targetable phenotypes in acute myeloid leukemia with complex karyotype
- Nat. Genet. 25 November 2024 | https://doi.org/10.1038/s41588-024-01999-x
- 2024.11
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In Vitro Modeling of Atherosclerosis Using iPSC-Derived Blood Vessel Organoids
- Adv. Healthc. Mater. 24 November 2024 | https://doi.org/10.1002/adhm.202400919
- 2024.11
- 의약학
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Conductive single enzyme nanocomposites prepared by in-situ growth of nanoscale polyaniline for high performance enzymatic bioelectrode
- Biosens. Bioelectron. 15 October 2024, 116841 | https://doi.org/10.1016/j.bios.2024.116841
- 2024.10
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Single-Molecule-Based, Label-Free Monitoring of Molecular Glue Efficacies for Promoting Protein-Protein Interactions Using YaxAB Nanopores
- ACS Nano Oct 31 2024, | https://doi.org/10.1021/acsnano.4c11436
- 2024.10
- 생명과학
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Revisiting Pyrimidine-Embedded Molecular Frameworks to Probe the Unexplored Chemical Space for Protein-Protein Interactions
- Acc. Chem. Res. Oct 31 2024, | https://doi.org/10.1021/acs.accounts.4c00452
- 2024.10
- 생명과학
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Arenicolide Family Macrolides Provide a New Therapeutic Lead Combating Multidrug-resistant Tuberculosis
- Angew. Chem.-Int. Edit. Oct 14 2024, | https://doi.org/10.1002/anie.202412994
- 2024.10
- 의약학
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Miniaturized Modular Click Chemistry-enabled Rapid Discovery of Unique SARS-CoV-2 Mpro Inhibitors With Robust Potency and Drug-like Profile
- Adv. Sci. Sep 25 2024, | https://doi.org/10.1002/advs.202404884
- 2024.09
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Drug Discovery and Screening Tool Development for Tauopathies by Focusing on Pathogenic Tau Repeat 3 Oligomers
- Angew. Chem.-Int. Edit. Sep 24 2024, | https://doi.org/10.1002/anie.202411942
- 2024.09
- 의약학
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Induction of steatosis in primary human hepatocytes recapitulates key pathophysiological aspects of metabolic dysfunction-associated steatotic liver d
- J. Hepatol. Jul 06 2024, S0168-8278(24)02347-X | https://doi.org/10.1016/j.jhep.2024.06.040
- 2024.07
- 생명과학
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Lubricant-Coated Organ-on-a-Chip for Enhanced Precision in Preclinical Drug Testing
- Small Jun 27 2024, | https://doi.org/10.1002/smll.202402431
- 2024.06
- 바이오·의료융합
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APACE: AlphaFold2 and advanced computing as a service for accelerated discovery in biophysics
- Proc. Natl. Acad. Sci. USA June 24, 2024, 121 (27) | https://doi.org/10.1073/pnas.2311888121
- 2024.06
- 생명과학
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Hirocidins, Cytotoxic Metabolites from Streptomyces hiroshimensis, Induce Mitochondrion-mediated Apoptosis
- Angew. Chem.-Int. Edit. Jun 19 2024, | https://doi.org/10.1002/anie.202405367
- 2024.06
- 의약학
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Organ-on-a-Chip Approach for Accelerating Blood-Brain Barrier Nanoshuttle Discovery
- ACS Nano May 22 2024, | https://doi.org/10.1021/acsnano.4c00994
- 2024.05
- 바이오·의료융합
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Nanofibril guided spheroid formation for enhanced pluripotency and differentiation of human induced pluripotent stem cells
- Chem. Eng. J. Available online 6 May 2024 | https://doi.org/10.1016/j.cej.2024.151900
- 2024.05
- 바이오·의료융합
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Community cohesion looseness in gene networks reveals individualized drug targets and resistance
- Brief. Bioinform. 15 April 2024 | https://doi.org/10.1093/bib/bbae175
- 2024.04
- 바이오·의료융합
