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1Cell penetrating peptides

'Cell penetrating peptides' 에 대한 통합검색결과 31건입니다.

한빛사31건

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Advances in transcription factor delivery: Target selection, engineering strategies, and delivery platforms
- J. Control. Release May 25 2025, S0168-3659(25)00505-X | https://doi.org/10.1016/j.jconrel.2025.113885
- 2025.05
- 의약학
Arginine-Rich Cell-Penetrating Peptides Induce Lipid Rearrangements for Their Active Translocation across Laterally Heterogeneous Membranes
- Adv. Sci. Jun 26 2024, | https://doi.org/10.1002/advs.202404563
- 2024.06
- 생명과학
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성균관대학교, 기초과학연구원

인체에는 뇌혈관장벽(Brain-Blood Barrier)이나 피부장벽(Skin Barrier)과 같은 생물학적 장벽이 존재하여 외부의 유해물질로부터 우리 몸을 보호합니다. 그러나 이러한 장벽으로 인해 약물 전달이 어려워집니다. 그 중 피부장벽은 피부의 최외각층 (Stratum corneum)으로 여러 겹의 죽은 각질세포와 세라마이드, 지방산, 콜레스테롤 등으로 구성되어 있어 500Da 이하의 저분자 물질의 경우 일부는 paracellular pathway를 통해 침투할 수 있지만 그 효율이 매우 떨어집니다.
- Adv. Healthc. Mater.
- 2024.03.11
Peptide-Drug Conjugate with Statistically Designed Transcellular Peptide for Psoriasis-Like Inflammation
- Adv. Healthc. Mater. Feb 29 2024, | https://doi.org/10.1002/adhm.202303480
- 2024.02
Bone-Targeted Delivery of Cell-Penetrating-RUNX2 Fusion Protein in Osteoporosis Model
- Adv. Sci. 2023 Aug 13;e2301570 | https://doi.org/10.1002/advs.202301570
- 2023.08
- 바이오·의료융합
- 노희광(Stanford University)
Cell-Type-Specific Intracellular Protein Delivery with Inactivated Botulinum Neurotoxin
- J. Am. Chem. Soc. 2023 May 10;145(18):10220-10226 | https://doi.org/10.1021/jacs.3c01145
- 2023.05
In vitro and in vivo suppression of SARS-CoV-2 replication by a modified, short, cell-penetrating peptide targeting the C-terminal domain of the viral
- J. Med. Virol. 2023 Mar;95(3):e28626 | https://doi.org/10.1002/jmv.28626
- 2023.03
- 정석환(University of Washington)
Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells
- ACS Appl. Mater. Interfaces 2023 Jan 11;15(1):106-119 | https://doi.org/10.1021/acsami.2c17802
- 2023.01
- Balachandran Manavalan(성균관대학교)
SiameseCPP: a sequence-based Siamese network to predict cell-penetrating peptides by contrastive learning
- Brief. Bioinform. 23 December 2022 | https://doi.org/10.1093/bib/bbac545
- 2022.12
- 생명과학
- 남소희(동덕여자대학교)
- 박성배(서울대학교 의과대학)
The complex of miRNA2861 and cell-penetrating, dimeric α-helical peptide accelerates the osteogenesis of mesenchymal stem cells
- Biomater. Res. Published: 29 December 2022 | https://doi.org/10.1186/s40824-022-00336-9
- 2022.12
- 의약학
Unleashing cell-penetrating peptide applications for immunotherapy
- Trends Mol. Med Available online 21 April 2022 | https://doi.org/10.1016/j.molmed.2022.03.010
- 2022.04
- 생명과학
- 정근옥(아주대학교 의과대학)
- 김용성(아주대학교)
Antibody-mediated delivery of a viral MHC-I epitope into the cytosol of target tumor cells repurposes virus-specific CD8+ T cells for cancer immunothe
- Mol. Cancer Published 22 April 2022 | https://doi.org/10.1186/s12943-022-01574-0
- 2022.04
- 생명과학
Synergistic gene delivery by self-assembled nanocomplexes using fusion peptide and calcium phosphate
- J. Control. Release Volume 338, 10 October 2021, Pages 284-294 | https://doi.org/10.1016/j.jconrel.2021.08.034
- 2021.10
- 생명과학
N-terminus-independent activation of c-Src via binding to a tetraspan(in) TM4SF5 in hepatocellular carcinoma is abolished by the TM4SF5 C-terminal pep
- Theranostics Published 2021-7-6, 11(16):8092-8111 | doi:10.7150/thno.58739
- 2021.07
- 의약학
Highly Efficient Photothermal Therapy with Cell-Penetrating Peptide-Modified Bumpy Au Triangular Nanoprisms using Low Laser Power and Low Probe Dose
- Nano Lett. December 17, 2020 | https://doi.org/10.1021/acs.nanolett.0c04386
- 2020.12
- 바이오·의료융합
A brain tumor-homing tetra-peptide delivers a nano-therapeutic for more effective treatment of a mouse model of glioblastoma
- Nanoscale Horiz. Issue 8, 5, 1213-1225, 2020 | https://doi.org/10.1039/D0NH00077A
- 2020.08
- 바이오·의료융합
- Balachandran Manavalan(아주대학교)
Empirical comparison and analysis of web-based cell-penetrating peptide prediction tools
- Brief. Bioinform. Volume 21, Issue 2, March 2020, Pages 408?420, | https://doi.org/10.1093/bib/bby124
- 2020.03
- 생명과학
Heterochiral Assembly of Amphiphilic Peptides Inside the Mitochondria for Supramolecular Cancer Therapeutics
- ACS Nano Publication Date:September 11, 2019 | https://doi.org/10.1021/acsnano.9b02522
- 2019.09
- 바이오·의료융합
Oligomer Formation Propensities of Dimeric Bundle Peptides Correlate with Cell Penetration Abilities
- ACS Central Sci. Publication Date (Web): July 10, 2018, 4 (7), pp 885-893 | DOI: 10.1021/acscentsci.8b00262
- 2018.07
- 바이오·의료융합
- Balachandran Manavalan(아주대학교)
- 이광(아주대학교)
Machine-Learning-Based Prediction of Cell-Penetrating Peptides and Their Uptake Efficiency with Improved Accuracy
- J. Proteome Res. Publication Date: June 12, 2018 | https://doi.org/10.1021/acs.jproteome.8b00148
- 2018.06
- 의약학