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'AKT' 에 대한 통합검색결과 516건입니다.

한빛사516건

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Cannabisin A and B from hemp seed hulls improve glucose homeostasis by re-engaging insulin, leptin, and AMPK pathways via selective PTP1B inhibition
- Phytomedicine Available online 9 March 2026, 158054 | https://doi.org/10.1016/j.phymed.2026.158054
- 2026.03
GPR54 regulates non-small cell lung cancer development via dopa decarboxylase
- Signal Transduct. Target. Ther. Mar 02 2026, 11 (1) 74 | https://doi.org/10.1038/s41392-026-02591-x
- 2026.03
NanoScript-Enabled Nonviral Transient Repression of Phosphatase and Tensin Homolog for Axonal Regeneration and Central Nervous System Injury Repair
- ACS Nano Feb 19 2026, | https://doi.org/10.1021/acsnano.5c13020
- 2026.02
- 바이오·의료융합
Methyl jasmonate promotes host defense by activating autophagy during Mycobacterium tuberculosis infection
- Phytomedicine Available online 11 February 2026, 157967 | https://doi.org/10.1016/j.phymed.2026.157967
- 2026.02
- 의약학
Schisandrin C alleviates depressive-like behaviors by modulating the AKT/CREB/BDNF pathway, the serotonin pathway of tryptophan metabolism, and the gu
- Phytomedicine Volume 150, January 2026, 157581 | https://doi.org/10.1016/j.phymed.2025.157581
- 2026.01
- 의약학
Rgnef regulates bone mass through the activation of RhoA and Rac1
- Exp. Mol. Med. Jan 23 2026, | https://doi.org/10.1038/s12276-025-01631-w
- 2026.01
- 생명과학
고동미

고려대학교 의과대학

삼중음성유방암(Triple-negative breast cancer, TNBC)은 전체 유방암 중 약 15~20%를 차지하며, 에스트로겐 수용체(ER), 프로게스테론 수용체(PR), 그리고 HER2 수용체가 모두 음성인 난치성 유방암입니다. 명확한 표적 분자가 존재하지 않기 때문에, 기존의 호르몬 치료나 HER2 표적치료제가 적용되지 않아 주로 세포독성 항암제에 의존하고 있으며, 치료 후에도 재발과 전이가 잦아 예후가 매우 불량합니다. 특히 치료 후에도 살아남는 암줄기세포(Cancer stem-like cells, CSCs)가 약물 내성과 종양 재발의 주요 원인으로 지목되면서, 이를 표적할 수 있는 새로운 치료 전략이 필요합니다.
- Exp. Hematol. Oncol.
- 2026.01.28
Gymnemantoside A Ameliorates Steroid-Induced Skeletal Muscle Atrophy via Bridging Glucocorticoid and Insulin Receptor Signalling
- J. Cachexia Sarcopenia Muscle Dec 2025, 16 (6) | https://doi.org/10.1002/jcsm.70118
- 2025.12
Targeting Progesterone Receptor Membrane Component 1 to Improve Muscle Development and Glucose Homeostasis
- J. Cachexia Sarcopenia Muscle Dec 2025, 16 (6) | https://doi.org/10.1002/jcsm.70121
- 2025.12
- 생명과학
Engineered extracellular vesicles reprogram T cells by targeting PD-1 and PHB1 signaling in inflammatory bowel disease
- Signal Transduct. Target. Ther. Dec 25 2025, 10 (1) | https://doi.org/10.1038/s41392-025-02516-0
- 2025.12
- 의약학
CXCL5 neutralization mitigates cancer cachexia by disrupting CAF-cancer cell crosstalk
- J. Biomed. Sci. Dec 15 2025, 32 (1) | https://doi.org/10.1186/s12929-025-01192-0
- 2025.12
- 의약학
- Xuangao Wu(호서대학교)
- 박선민(호서대학교)
Herba Patriniae with probiotics targets Escherichia fergusonii and the 5-hydroxytryptophan?trimethylamine N-oxide axis in Parkinson’s disease
- Phytomedicine Available online 30 December 2025, 157758 | https://doi.org/10.1016/j.phymed.2025.157758
- 2025.12
Atraric acid and atranorin inhibit breast cancer energy metabolism and immune evasion through PI3K/AKT/Bcl-xL
- Phytomedicine Available online 15 November 2025, 157560 | https://doi.org/10.1016/j.phymed.2025.157560
- 2025.11
- 의약학
- 강래형(University of Wisconsin-Madison, 단국대학교)
Precise Ratiometric Drug Delivery for the Treatment of Triple-Negative Breast Cancer
- ACS Nano Nov 19 2025, | https://doi.org/10.1021/acsnano.5c13083
- 2025.11
- 의약학
PYCR1 drives lung cancer progression through functional interactions with EGFR and TLR signaling pathways
- Exp. Mol. Med. 18 November 2025 | https://doi.org/10.1038/s12276-025-01577-z
- 2025.11
- 의약학
Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review
- Adv. Healthc. Mater. Nov 17 2025, | https://doi.org/10.1002/adhm.202503676
- 2025.11
- 바이오·의료융합
- 박준규(경희대학교)
  Interview
- 이경진(경희대학교 한의과대학 본초학교실)
Vasorelaxant and Antihypertensive Effects of the Cibotii Rhizoma Hydroethanolic Extract via the PI3K/AKT/eNOS Pathway
- Phytomedicine Available online 21 October 2025, 157437 | https://doi.org/10.1016/j.phymed.2025.157437
- 2025.10
- 의약학
A novel TM4SF4-targeting therapeutic antibody candidate with antitumor activity by blocking IGF1R and CD44 signaling and downregulating PD-L1 and B7-H
- Theranostics 2025-10-28;16(4):1762-1781. | doi:10.7150/thno.113347
- 2025.10
- 의약학
- 김재윤(한국생명공학연구원)
  Interview
- 조이숙(한국생명공학연구원, 과학기술연합대학원대학교)
Cell-free secretome of CD56brightCD16bright directly reprogrammed NK cells enhances wound healing via CCL3/4/5-CCR5 signaling
- Theranostics 2025-10-5; 16(2):952-969 | doi:10.7150/thno.120219
- 2025.10
- 생명과학
Synergistic ion-releasing nanoparticles as a therapeutic platform for modulating adult stem cell activity in wound healing
- Biomater. Res. 27 Oct 2025 | https://doi.org/10.34133/bmr.0281
- 2025.10
- 바이오·의료융합