통합검색
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'α-synuclein' 에 대한 통합검색결과 99건입니다.
한빛사99건
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α-Synuclein pathology as a target in neurodegenerative diseases
- Nat. Rev. Neurol. 28 November 2024 | https://doi.org/10.1038/s41582-024-01043-w
- 2024.11
- 의약학
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Blood-Based Nanoparticle-Enhanced Quaking-Induced Conversion (Nano-QuIC): Inhibitor-Resistant Detection of Seeding Activity in Patients Diagnosed with
- Nano Lett. Nov 01 2024, | https://doi.org/10.1021/acs.nanolett.4c03768
- 2024.11
- 바이오·의료융합
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Olfactory deficit and gastrointestinal dysfunction precede motor abnormalities in alpha-Synuclein G51D knock-in mice
- Proc. Natl. Acad. Sci. USA Sep 24 2024, 121 (39) e2406479121 | https://doi.org/10.1073/pnas.2406479121
- 2024.09
- 생명과학
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Modeling Lewy body disease with SNCA triplication iPSC-derived cortical organoids and identifying therapeutic drugs
- Sci. Adv. Sep 13 2024, 10 (37) | https://doi.org/10.1126/sciadv.adk3700
- 2024.09
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Amyloid-β-activated microglia can induce compound proteinopathies
- Brain Aug 28 2024, awae221 | https://doi.org/10.1093/brain/awae221
- 2024.08
- 의약학
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Gba1 E326K renders motor and non-motor symptoms with pathologic α-syn, tau and glial activation
- Brain Jul 08 2024, awae222 | https://doi.org/10.1093/brain/awae222
- 2024.07
- 생명과학
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The autoimmune response induced by α-synuclein peptides drives neuronal cell death and glial cell activation
- J. Autoimmun. May 23 2024, 147 S0896-8411(24)00090-8 | https://doi.org/10.1016/j.jaut.2024.103256
- 2024.05
- 생명과학
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Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
- Nat. Commun. May 31 2024, 15 (1) 4663 | https://doi.org/10.1038/s41467-024-49016-3
- 2024.05
- 생명과학
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CRISPR-based identification of N-terminal acetylation in synucleinopathies
- Trends Neurosci. Mar 28 2024, S0166-2236(24)00043-2 | https://doi.org/10.1016/j.tins.2024.03.006
- 2024.03
- 의약학
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Preparation of human astrocytes with potent therapeutic functions from human pluripotent stem cells using ventral midbrain patterning
- J. Adv. Res. Mar 21 2024, S2090-1232(24)00112-7 | https://doi.org/10.1016/j.jare.2024.03.012
- 2024.03
- 의약학
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Multifactorial drug carrier system bringing both chemical and physical therapeutics to the treatment of tumor heterogeneity
- J. Control. Release Mar 18 2024, S0168-3659(24)00186-X | https://doi.org/10.1016/j.jconrel.2024.03.033
- 2024.03
- 바이오·의료융합
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Nanoplastics exacerbate Parkinson‘s disease symptoms in C. elegans and human cells
- J. Hazard. Mater. Available online 18 December 2023 | https://doi.org/10.1016/j.jhazmat.2023.133289
- 2023.12
- 생명과학
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P. mirabilis-derived pore-forming haemolysin, HpmA drives intestinal alpha-synuclein aggregation in a mouse model of neurodegeneration
- EBioMedicine Nov 22 2023, 98 S2352-3964(23)00453-X | https://doi.org/10.1016/j.ebiom.2023.104887
- 2023.11
- 의약학
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A selective ER-phagy exerts neuroprotective effects via modulation of α-synuclein clearance in parkinsonian models.
- Proc. Natl. Acad. Sci. USA Sep 12 2023, 120 (37) | https://doi.org/10.1073/pnas.2221929120
- 2023.09
- 의약학
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Neuroprotective effects of osmotin in Parkinson‘s disease-associated pathology via the AdipoR1/MAPK/AMPK/mTOR signaling pathways
- J. Biomed. Sci. 2023 Aug 11;30(1):66 | https://doi.org/10.1186/s12929-023-00961-z
- 2023.08
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Targeted degradation of α-synuclein aggregates in Parkinson’s disease using the AUTOTAC technology
- Mol. Neurodegener. 2023 Jun 24;18(1):41 | https://doi.org/10.1186/s13024-023-00630-7
- 2023.06
- 생명과학
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Truncation or proteolysis of α-synuclein in Parkinsonism
- Ageing Res. Rev. 2023 Jun 5;101978 | https://doi.org/10.1016/j.arr.2023.101978
- 2023.06
- 의약학
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Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease
- Nat. Commun. Published: 19 April 2023 | https://doi.org/10.1038/s41467-023-37464-2
- 2023.04
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Biomimetically Engineered Amyloid-Shelled Gold Nanocomplexes for Discovering α-Synuclein Oligomer-Degrading Drugs
- ACS Appl. Mater. Interfaces December 22, 2022 | https://doi.org/10.1021/acsami.2c14650
- 2022.12
- 바이오·의료융합
