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통합검색

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1 Transcriptome analysis

' Transcriptome analysis' 에 대한 통합검색결과 400건입니다.

한빛사400건

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- 신종오(전남대학교)
A systems-level atlas of carbon-response transcriptional states in Escherichia coli
- Proc. Natl. Acad. Sci. USA Jul 07 2026, 123 (27) | https://doi.org/10.1073/pnas.2531884123
- 2026.07
- 생명과학
Integrative genomic analysis of 21 orofacial diseases identifies shared genetic architecture with systemic diseases
- Nat. Commun. Jun 04 2026, | https://doi.org/10.1038/s41467-026-73925-0
- 2026.06
- 의약학
Malignant epithelial states drive immune dysfunction in ampulla of Vater carcinoma
- Biomark. Res. Jun 29 2026, | https://doi.org/10.1186/s40364-026-00961-9
- 2026.06
- 바이오·의료융합
Machine learning-based integration of transcriptome and digital pathology for predicting chemoresistance in muscle-invasive bladder cancer
- Exp. Mol. Med. 08 May 2026 | https://doi.org/10.1038/s12276-026-01718-y
- 2026.05
- 의약학
Chamber-Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and
- Adv. Healthc. Mater. May 06 2026, | https://doi.org/10.1002/adhm.202503802
- 2026.05
- 바이오·의료융합
- 배순형(서울대학교)
  Interview
- 서필준(서울대학교)
Stem cell activity is linked to a transient acquisition of pluripotency during callus proliferation
- Nat. Commun. 19 May 2026 | https://doi.org/10.1038/s41467-026-73124-x
- 2026.05
- 생명과학
Defective autophagy in GNE myopathy is rescued by inhibition of noncanonical Akt-mTORC1 activation across multiple isogenic models
- Exp. Mol. Med. Apr 10 2026, | https://doi.org/10.1038/s12276-026-01701-7
- 2026.04
- 의약학
Human brain and organoid transcriptomes reveal key receptor tyrosine kinase pathways and genetic signatures in Alzheimer‘s disease
- Exp. Mol. Med. 15 April 2026 | https://doi.org/10.1038/s12276-026-01684-5
- 2026.04
- 의약학
Peroxiredoxin Ⅲ safeguards cardiac function against doxorubicin by regulating mitochondrial quality control via H2O2 detoxification
- Redox Biol. Available online 16 April 2026, 104176 | https://doi.org/10.1016/j.redox.2026.104176
- 2026.04
- 의약학
Delineation of the heterogeneity underlying genomic instability in hereditary breast cancers reveals four disease subtypes
- Exp. Mol. Med. Apr 16 2026, | https://doi.org/10.1038/s12276-026-01693-4
- 2026.04
- 생명과학
장범진

성균관대학교 삼성융합의과학원

이번 연구는 대규모 유전체 데이터와 단일세포 RNA 시퀀싱 데이터를 통합하여, 질병과 연관된 유전 변이가 세포 유형별로 어떻게 작동하는지를 체계적으로 규명한 것이 특징입니다. 기존의 전장 유전체 연관성 분석(GWAS)을 통해 수많은 질병 관련 유전 변이가 밝혀졌지만, 이들이 실제로 어떤 세포에서 어떤 유전자를 통해 기능하는지는 대부분 명확히 규명되지 않았습니다. 특히 기존 연구는 조직 평균 수준의 전사체(bulk transcriptome)에 의존하거나, 단일세포 데이터의 샘플 수가 제한되어 통계적 한계를 가지는 문제가 있었습니다.
- Nat. Genet.
- 2026.04.15
- 박봉수(National Institute on Aging, NIH)
Chromatin reorganization drives overexpression of a Btaf1 variant underpinning hematopoietic aging
- Nat. Commun. 18 March 2026 | https://doi.org/10.1038/s41467-026-70787-4
- 2026.03
Cannabisin A and B from hemp seed hulls improve glucose homeostasis by re-engaging insulin, leptin, and AMPK pathways via selective PTP1B inhibition
- Phytomedicine Available online 9 March 2026, 158054 | https://doi.org/10.1016/j.phymed.2026.158054
- 2026.03
De novo stolon organogenesis in potato leaf callus elicited by Agrobacterium tumefaciens stimulus
- J. Integr. Plant Biol. Mar 01 2026, | https://doi.org/10.1111/jipb.70203
- 2026.03
- 생명과학
- 최승지(고려대학교 의과대학)
  Interview
- 최정민(고려대학교 의과대학)
Integrated mutational landscape analysis of endometrial stromal sarcoma
- Proc. Natl. Acad. Sci. USA Feb 03 2026, 123 (5) | https://doi.org/10.1073/pnas.2531105123
- 2026.02
- 의약학
- 양동찬(KAIST, Duke University Medical Center)
- 정인경(KAIST)
Trimodal single-cell profiling of transcriptome, epigenome and 3D genome in complex tissues with scHiCAR
- Nat. Biotechnol. Published: 19 February 2026 | https://doi.org/10.1038/s41587-026-03013-7
- 2026.02
- 생명과학
Single-cell and spatial transcriptomics unveil myeloid-lymphoid crosstalk and the dermal immune niche underlying palmoplantar pustulosis
- J. Allergy Clin. Immunol. Feb 23 2026, S0091-6749(26)00128-4 | https://doi.org/10.1016/j.jaci.2026.01.028
- 2026.02
- 의약학
Pharmacological chaperones mitigate noise-induced hearing loss by attenuating sustained PERK activation
- Proc. Natl. Acad. Sci. USA Jan 27 2026, 123 (4) | https://doi.org/10.1073/pnas.2421591123
- 2026.01
- 생명과학
- 이혜림(Stanford University School of Medicine)
EcDNA-borne structural variants drive oncogenic fusion transcript amplification
- Cell January 07, 2026 | https://doi.org/10.1016/j.cell.2025.12.009
- 2026.01
- 생명과학
Therapeutic Potential of HSP90 Inhibitor 17-DMAG in Regulating METTL3 for Kidney Fibrosis Treatment
- J. Am. Soc. Nephrol. Jan 26 2026, | https://doi.org/10.1681/ASN.0000000975
- 2026.01
- 의약학